메뉴 건너뛰기




Volumn 86, Issue 6, 2012, Pages 3337-3346

The Amino Acid Linker between the Endonuclease and Helicase Domains of Adeno-Associated Virus Type 5 Rep Plays a Critical Role in DNA-Dependent Oligomerization

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DOUBLE STRANDED DNA; ENDONUCLEASE; HELICASE; SINGLE STRANDED DNA;

EID: 84857933340     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06775-11     Document Type: Article
Times cited : (17)

References (49)
  • 1
    • 30344435922 scopus 로고    scopus 로고
    • Impact of capsid conformation and Rep-capsid interactions on adeno-associated virus type 2 genome packaging
    • Bleker S, Pawlita M, Kleinschmidt JA. 2006. Impact of capsid conformation and Rep-capsid interactions on adeno-associated virus type 2 genome packaging. J. Virol. 80:810-820.
    • (2006) J. Virol. , vol.80 , pp. 810-820
    • Bleker, S.1    Pawlita, M.2    Kleinschmidt, J.A.3
  • 2
    • 71449107031 scopus 로고    scopus 로고
    • The Mcm complex: unwinding the mechanism of a replicative helicase
    • Bochman ML, Schwacha A. 2009. The Mcm complex: unwinding the mechanism of a replicative helicase. Microbiol. Mol. Biol. Rev. 73:652- 683.
    • (2009) Microbiol. Mol. Biol. Rev. , vol.73 , pp. 652-683
    • Bochman, M.L.1    Schwacha, A.2
  • 3
    • 67349214924 scopus 로고    scopus 로고
    • Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains
    • Boer DR, et al. 2009. Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains. EMBO J. 28:1666 -1678.
    • (2009) EMBO J , vol.28 , pp. 1666-1678
    • Boer, D.R.1
  • 4
    • 78650240871 scopus 로고    scopus 로고
    • DNA replication: making two forks from one prereplication complex
    • Botchan M, Berger J. 2010. DNA replication: making two forks from one prereplication complex. Mol. Cell 40:860-861.
    • (2010) Mol. Cell , vol.40 , pp. 860-861
    • Botchan, M.1    Berger, J.2
  • 5
    • 0032853990 scopus 로고    scopus 로고
    • Rep-mediated nicking of the adenoassociated virus origin requires two biochemical activities DNA helicase activity and transesterification
    • Brister JR, Muzyczka N. 1999. Rep-mediated nicking of the adenoassociated virus origin requires two biochemical activities, DNA helicase activity and transesterification. J. Virol. 73:9325-9336.
    • (1999) J. Virol. , vol.73 , pp. 9325-9336
    • Brister, J.R.1    Muzyczka, N.2
  • 6
    • 0024442216 scopus 로고
    • Mutation of an AUG codon in the adeno-asociated virus rep gene: effects on viral DNA replication
    • Chejanovsky N, Carter BJ. 1989. Mutation of an AUG codon in the adeno-asociated virus rep gene: effects on viral DNA replication. Virol. 173:120 -128.
    • (1989) Virol , vol.173 , pp. 120-128
    • Chejanovsky, N.1    Carter, B.J.2
  • 7
    • 0025218471 scopus 로고
    • Mutation of a consensus purine nucleotide binding site in the adeno-associated virus rep gene generates a dominant-negative phenotype for DNA replication
    • Chejanovsky N, Carter BJ. 1990. Mutation of a consensus purine nucleotide binding site in the adeno-associated virus rep gene generates a dominant-negative phenotype for DNA replication. J. Virol. 64:1764- 1770.
    • (1990) J. Virol. , vol.64 , pp. 1764-1770
    • Chejanovsky, N.1    Carter, B.J.2
  • 8
    • 84857944812 scopus 로고    scopus 로고
    • Reference deleted
    • Reference deleted
  • 9
    • 33846242147 scopus 로고    scopus 로고
    • Coupled ATP and DNA binding of adenoassociated virus Rep40 helicase
    • Dignam SS, et al. 2007. Coupled ATP and DNA binding of adenoassociated virus Rep40 helicase. Biochem. 46:568 -576.
    • (2007) Biochem , vol.46 , pp. 568-576
    • Dignam, S.S.1
  • 10
    • 34249714209 scopus 로고    scopus 로고
    • Activation of the ATPase activity of adeno-associated virus Rep68 and Rep78
    • Dignam SS, Correia JJ, Nada SE, Trempe JP, Dignam JD. 2007. Activation of the ATPase activity of adeno-associated virus Rep68 and Rep78. Biochem. 46:6364-6374.
    • (2007) Biochem , vol.46 , pp. 6364-6374
    • Dignam, S.S.1    Correia, J.J.2    Nada, S.E.3    Trempe, J.P.4    Dignam, J.D.5
  • 11
    • 0032826095 scopus 로고    scopus 로고
    • Adenoassociated virus type 2 protein interactions: formation of preencapsidation complexes
    • Dubielzig R, King JA, Weger S, Kern A, Kleinschmidt JA. 1999. Adenoassociated virus type 2 protein interactions: formation of preencapsidation complexes. J. Virol. 73:8989-8998.
    • (1999) J. Virol. , vol.73 , pp. 8989-8998
    • Dubielzig, R.1    King, J.A.2    Weger, S.3    Kern, A.4    Kleinschmidt, J.A.5
  • 12
    • 33746375404 scopus 로고    scopus 로고
    • Mechanism of DNA translocation in a replicative hexameric helicase
    • Enemark EJ, Joshua-Tor L. 2006. Mechanism of DNA translocation in a replicative hexameric helicase. Nature 442:270 -275.
    • (2006) Nature , vol.442 , pp. 270-275
    • Enemark, E.J.1    Joshua-Tor, L.2
  • 13
    • 33745041480 scopus 로고    scopus 로고
    • Evolutionary relationships and structural mechanisms of AAA+ proteins
    • Erzberger JP, Berger JM. 2006. Evolutionary relationships and structural mechanisms of AAA+ proteins. Annu. Rev. Biophys. Biomol. Struct. 35: 93-114.
    • (2006) Annu. Rev. Biophys. Biomol. Struct. , vol.35 , pp. 93-114
    • Erzberger, J.P.1    Berger, J.M.2
  • 14
    • 0033548196 scopus 로고    scopus 로고
    • Biochemical and electron microscopic image analysis of the hexameric E1 helicase
    • Fouts ET, Yu X, Egelman EH, Botchan MR. 1999. Biochemical and electron microscopic image analysis of the hexameric E1 helicase. J. Biol. Chem. 274:4447- 4458.
    • (1999) J. Biol. Chem. , vol.274 , pp. 4447-4458
    • Fouts, E.T.1    Yu, X.2    Egelman, E.H.3    Botchan, M.R.4
  • 15
    • 0019707963 scopus 로고
    • SPIDER: a modular software system for electron image processing
    • Frank J, Shimkin B, Dowse H. 1981. SPIDER: a modular software system for electron image processing. Ultramicroscopy 6:343-358.
    • (1981) Ultramicroscopy , vol.6 , pp. 343-358
    • Frank, J.1    Shimkin, B.2    Dowse, H.3
  • 16
    • 0346243986 scopus 로고    scopus 로고
    • Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication
    • Gomez-Lorenzo MG, et al. 2003. Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication. EMBO J. 22:6205- 6213.
    • (2003) EMBO J , vol.22 , pp. 6205-6213
    • Gomez-Lorenzo, M.G.1
  • 17
    • 0025261685 scopus 로고
    • A new superfamily of putative NTP-binding domains encoded by genomes of small DNA and RNA viruses
    • Gorbalenya AE, Koonin EV, Wolf YI. 1990. A new superfamily of putative NTP-binding domains encoded by genomes of small DNA and RNA viruses. FEBS Lett. 262:145-148.
    • (1990) FEBS Lett , vol.262 , pp. 145-148
    • Gorbalenya, A.E.1    Koonin, E.V.2    Wolf, Y.I.3
  • 18
    • 77957323822 scopus 로고    scopus 로고
    • Adeno-associated virus: a key to the human genome?
    • Henckaerts E, Linden RM. 2010. Adeno-associated virus: a key to the human genome? Future Virol. 5:555-574.
    • (2010) Future Virol , vol.5 , pp. 555-574
    • Henckaerts, E.1    Linden, R.M.2
  • 19
    • 84857982053 scopus 로고    scopus 로고
    • Reference deleted
    • Reference deleted
  • 20
    • 0036671409 scopus 로고    scopus 로고
    • Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep
    • Hickman AB, Ronning DR, Kotin RM, Dyda F. 2002. Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep. Mol. Cell 10:327-337.
    • (2002) Mol. Cell , vol.10 , pp. 327-337
    • Hickman, A.B.1    Ronning, D.R.2    Kotin, R.M.3    Dyda, F.4
  • 21
    • 1242339574 scopus 로고    scopus 로고
    • The nuclease domain of adeno-associated virus Rep coordinates replication initiation using two distinct DNA recognition interfaces
    • Hickman AB, Ronning DR, Perez ZN, Kotin RM, Dyda F. 2004. The nuclease domain of adeno-associated virus Rep coordinates replication initiation using two distinct DNA recognition interfaces. Mol. Cell 13: 403-414.
    • (2004) Mol. Cell , vol.13 , pp. 403-414
    • Hickman, A.B.1    Ronning, D.R.2    Perez, Z.N.3    Kotin, R.M.4    Dyda, F.5
  • 22
    • 13844254123 scopus 로고    scopus 로고
    • Binding and unwinding: SF3 viral helicases
    • Hickman AB, Dyda F. 2005. Binding and unwinding: SF3 viral helicases. Curr. Opin. Struct. Biol. 15:77- 85.
    • (2005) Curr. Opin. Struct. Biol. , vol.15 , pp. 77-85
    • Hickman, A.B.1    Dyda, F.2
  • 23
    • 0025362618 scopus 로고
    • The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity
    • Im DS, Muzyczka N. 1990. The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity. Cell 61:447- 457.
    • (1990) Cell , vol.61 , pp. 447-457
    • Im, D.S.1    Muzyczka, N.2
  • 24
    • 0041630781 scopus 로고    scopus 로고
    • Crystal structure of the SF3 helicase from adenoassociated virus type 2
    • James JA, et al. 2003. Crystal structure of the SF3 helicase from adenoassociated virus type 2. Structure 11:1025-1035.
    • (2003) Structure , vol.11 , pp. 1025-1035
    • James, J.A.1
  • 25
    • 4344596245 scopus 로고    scopus 로고
    • Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases
    • James JA, Aggarwal AK, Linden RM, Escalante CR. 2004. Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases. Proc. Natl. Acad. Sci. U. S. A. 101:12455-12460.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 12455-12460
    • James, J.A.1    Aggarwal, A.K.2    Linden, R.M.3    Escalante, C.R.4
  • 26
    • 0035875669 scopus 로고    scopus 로고
    • DNA helicasemediated packaging of adeno-associated virus type 2 genomes into preformed capsids
    • King JA, Dubielzig R, Grimm D, Kleinschmidt JA. 2001. DNA helicasemediated packaging of adeno-associated virus type 2 genomes into preformed capsids. EMBO J. 20:3282-3291.
    • (2001) EMBO J , vol.20 , pp. 3282-3291
    • King, J.A.1    Dubielzig, R.2    Grimm, D.3    Kleinschmidt, J.A.4
  • 27
    • 0025214094 scopus 로고
    • Site-specific integration by adeno-associated virus
    • Kotin RM, et al. 1990. Site-specific integration by adeno-associated virus. Proc. Natl. Acad. Sci. U. S. A. 87:2211-2215.
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 2211-2215
    • Kotin, R.M.1
  • 28
    • 0027092001 scopus 로고
    • Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination
    • Kotin RM, Linden RM, Berns KI. 1992. Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination. EMBO J. 11:5071-5078.
    • (1992) EMBO J , vol.11 , pp. 5071-5078
    • Kotin, R.M.1    Linden, R.M.2    Berns, K.I.3
  • 29
    • 30544447100 scopus 로고    scopus 로고
    • Robust colorimetric assays for dynamin's basal and stimulated GTPase activities
    • Leonard M, Song BD, Ramachandran R, Schmid SL. 2005. Robust colorimetric assays for dynamin's basal and stimulated GTPase activities. Methods Enzymol. 404:490 -503.
    • (2005) Methods Enzymol , vol.404 , pp. 490-503
    • Leonard, M.1    Song, B.D.2    Ramachandran, R.3    Schmid, S.L.4
  • 30
    • 0038700763 scopus 로고    scopus 로고
    • Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen
    • Li D, et al. 2003. Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen. Nature 423:512-518.
    • (2003) Nature , vol.423 , pp. 512-518
    • Li, D.1
  • 31
    • 0029836836 scopus 로고    scopus 로고
    • The recombination signals for adeno-associated virus site-specific integration
    • Linden RM, Winocour E, Berns KI. 1996. The recombination signals for adeno-associated virus site-specific integration. Proc. Natl. Acad. Sci. U. S. A. 93:7966 -7972.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 7966-7972
    • Linden, R.M.1    Winocour, E.2    Berns, K.I.3
  • 32
    • 0026058683 scopus 로고
    • The zinc finger region of simian virus 40 large T antigen is needed for hexamer assembly and origin melting
    • Loeber G, et al. 1991. The zinc finger region of simian virus 40 large T antigen is needed for hexamer assembly and origin melting. J. Virol. 65: 3167-3174.
    • (1991) J. Virol. , vol.65 , pp. 3167-3174
    • Loeber, G.1
  • 33
    • 0033377664 scopus 로고    scopus 로고
    • EMAN: semiautomated software for high-resolution single-particle reconstructions
    • Ludtke SJ, Baldwin PR, Chiu W. 1999. EMAN: semiautomated software for high-resolution single-particle reconstructions. J. Struct. Biol. 128:82-97.
    • (1999) J. Struct. Biol. , vol.128 , pp. 82-97
    • Ludtke, S.J.1    Baldwin, P.R.2    Chiu, W.3
  • 34
    • 70049085266 scopus 로고    scopus 로고
    • DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68
    • Mansilla-Soto J, et al. 2009. DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68. PLoS Pathog. 5:e1000513.
    • (2009) PLoS Pathog , vol.5
    • Mansilla-Soto, J.1
  • 35
    • 0024550638 scopus 로고
    • ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication
    • Mastrangelo IA, et al. 1989. ATP-dependent assembly of double hexamers of SV40 T antigen at the viral origin of DNA replication. Nature 338: 658-662.
    • (1989) Nature , vol.338 , pp. 658-662
    • Mastrangelo, I.A.1
  • 36
    • 84857944810 scopus 로고    scopus 로고
    • Reference deleted
    • Reference deleted
  • 37
    • 0033786801 scopus 로고    scopus 로고
    • Structure and function of hexameric helicases
    • Patel SS, Picha KM. 2000. Structure and function of hexameric helicases. Annu. Rev. Biochem. 69:651- 697.
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 651-697
    • Patel, S.S.1    Picha, K.M.2
  • 38
    • 0026070440 scopus 로고
    • Targeted integration of adeno-associated virus (AAV) into human chromosome 19
    • Samulski RJ, et al. 1991. Targeted integration of adeno-associated virus (AAV) into human chromosome 19. EMBO J. 10:3941-3950.
    • (1991) EMBO J , vol.10 , pp. 3941-3950
    • Samulski, R.J.1
  • 39
    • 0029928871 scopus 로고    scopus 로고
    • SUPRIM: easily modified image processing software
    • Schroeter JP, Bretaudiere JP. 1996. SUPRIM: easily modified image processing software. J. Struct. Biol. 116:131-137.
    • (1996) J. Struct. Biol. , vol.116 , pp. 131-137
    • Schroeter, J.P.1    Bretaudiere, J.P.2
  • 40
    • 0031926580 scopus 로고    scopus 로고
    • The papillomavirus E1 protein forms a DNA-dependent hexameric complex with ATPase and DNA helicase activities
    • Sedman J, Stenlund A. 1998. The papillomavirus E1 protein forms a DNA-dependent hexameric complex with ATPase and DNA helicase activities. J. Virol. 72:6893- 6897.
    • (1998) J. Virol. , vol.72 , pp. 6893-6897
    • Sedman, J.1    Stenlund, A.2
  • 41
    • 34548638261 scopus 로고    scopus 로고
    • Structure and mechanism of helicases and nucleic acid translocases
    • Singleton MR, Dillingham MS, Wigley DB. 2007. Structure and mechanism of helicases and nucleic acid translocases. Annu. Rev. Biochem. 76:23-50.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 23-50
    • Singleton, M.R.1    Dillingham, M.S.2    Wigley, D.B.3
  • 42
    • 0030947409 scopus 로고    scopus 로고
    • The Rep78 gene product of adeno-associated virus (AAV) self-associates to form a hexameric complex in the presence of AAV ori sequences
    • Smith RH, Spano AJ, Kotin RM. 1997. The Rep78 gene product of adeno-associated virus (AAV) self-associates to form a hexameric complex in the presence of AAV ori sequences. J. Virol. 71:4461- 4471.
    • (1997) J. Virol. , vol.71 , pp. 4461-4471
    • Smith, R.H.1    Spano, A.J.2    Kotin, R.M.3
  • 43
    • 0031903004 scopus 로고    scopus 로고
    • The Rep52 gene product of adeno-associated virus is a DNA helicase with 3=-to-5= polarity
    • Smith RH, Kotin RM. 1998. The Rep52 gene product of adeno-associated virus is a DNA helicase with 3=-to-5= polarity. J. Virol. 72:4874-4881.
    • (1998) J. Virol. , vol.72 , pp. 4874-4881
    • Smith, R.H.1    Kotin, R.M.2
  • 44
    • 0030752558 scopus 로고    scopus 로고
    • Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome
    • Surosky RT, et al. 1997. Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome. J. Virol. 71:7951-7959.
    • (1997) J. Virol. , vol.71 , pp. 7951-7959
    • Surosky, R.T.1
  • 45
    • 0033852428 scopus 로고    scopus 로고
    • Identification of domains of the human papillomavirus type 11 E1 helicase involved in oligomerization and binding to the viral origin
    • Titolo S, et al. 2000. Identification of domains of the human papillomavirus type 11 E1 helicase involved in oligomerization and binding to the viral origin. J. Virol. 74:7349 -7361.
    • (2000) J. Virol. , vol.74 , pp. 7349-7361
    • Titolo, S.1
  • 46
    • 0032975564 scopus 로고    scopus 로고
    • Charged-to-alanine scanning mutagenesis of the N-terminal half of adeno-associated virus type 2 Rep78 protein
    • Urabe M, et al. 1999. Charged-to-alanine scanning mutagenesis of the N-terminal half of adeno-associated virus type 2 Rep78 protein. J. Virol. 73:2682-2693.
    • (1999) J. Virol. , vol.73 , pp. 2682-2693
    • Urabe, M.1
  • 47
    • 9644258644 scopus 로고    scopus 로고
    • Residues within the B' motif are critical for DNA binding by the superfamily 3 helicase Rep40 of adeno-associated virus type 2
    • Yoon-Robarts M, et al. 2004. Residues within the B' motif are critical for DNA binding by the superfamily 3 helicase Rep40 of adeno-associated virus type 2. J. Biol. Chem. 279:50472-50481.
    • (2004) J. Biol. Chem. , vol.279 , pp. 50472-50481
    • Yoon-Robarts, M.1
  • 48
    • 0030846525 scopus 로고    scopus 로고
    • Mutational analysis of the adeno-associated virus type 2 Rep68 protein helicase motifs
    • Walker SL, Wonderling RS, Owens RA. 1997. Mutational analysis of the adeno-associated virus type 2 Rep68 protein helicase motifs. J. Virol. 71: 6996-7004.
    • (1997) J. Virol. , vol.71 , pp. 6996-7004
    • Walker, S.L.1    Wonderling, R.S.2    Owens, R.A.3
  • 49
    • 55549132236 scopus 로고    scopus 로고
    • The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins
    • Zhang X, Wigley DB. 2008. The 'glutamate switch' provides a link between ATPase activity and ligand binding in AAA+ proteins. Nature Struct. Mol. Biol. 15:1223-1227.
    • (2008) Nature Struct. Mol. Biol. , vol.15 , pp. 1223-1227
    • Zhang, X.1    Wigley, D.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.