The interdomain linker of AAV-2 Rep68 is an integral part of its oligomerization domain: Role of a conserved SF3 helicase residue in oligomerization

PLoS Pathogens

Volumn 8, Issue 6, 2012, Pages

  Zarate Perez, Francisco ^a   Bardelli, Martino ^b   Burgner II, John W ^a   Villamil Jarauta, Maria ^a   Das, Kanni ^a   Kekilli, Demet ^c   Mansilla Soto, Jorge ^d   Linden, R Michael ^b,e   Escalante, Carlos R ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c UNIVERSITY OF THE WEST OF ENGLAND   (United Kingdom)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; OLIGOMER; PROTEIN REP68; SF3 HELICASE; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; REP PROTEINS, ADENO ASSOCIATED VIRUS 2; REP PROTEINS, ADENO-ASSOCIATED VIRUS 2; VIRUS PROTEIN;

ADENO ASSOCIATED VIRUS; ARTICLE; ENZYME STRUCTURE; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; VIRUS INFECTIVITY; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

ADENO-ASSOCIATED VIRUS; ADENO-ASSOCIATED VIRUS - 2;

DEPENDOVIRUS; DNA HELICASES; DNA-BINDING PROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; VIRAL PROTEINS;

EID: 84864056927     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002764     Document Type: Article

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