-
1
-
-
84964306129
-
Mass spectrometry imaging in drug development
-
Nilsson A, Goodwin RJ, Shariatgorji M, Vallianatou T, Webborn PJ, Andren PE. Mass spectrometry imaging in drug development. Anal. Chem. 87(3), 1437-1455 (2015
-
(2015)
Anal. Chem
, vol.87
, Issue.3
, pp. 1437-1455
-
-
Nilsson, A.1
Goodwin, R.J.2
Shariatgorji, M.3
Vallianatou, T.4
Webborn, P.J.5
Andren, P.E.6
-
2
-
-
84865200761
-
Mass spectrometry imaging for drug distribution studies
-
Prideaux B, Stoeckli M. Mass spectrometry imaging for drug distribution studies. J. Proteomics 75(16), 4999-5013 (2012
-
(2012)
J. Proteomics
, vol.75
, Issue.16
, pp. 4999-5013
-
-
Prideaux, B.1
Stoeckli, M.2
-
3
-
-
77449124587
-
Autoradiography maldi-ms and sims-ms imaging in pharmaceutical discovery and development
-
Solon E, Schweitzer A, Stoeckli M, Prideaux B. Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development. AAPS J. 12(1), 11-26 (2010
-
(2010)
AAPS J.
, vol.12
, Issue.1
, pp. 11-26
-
-
Solon, E.1
Schweitzer, A.2
Stoeckli, M.3
Prideaux, B.4
-
4
-
-
0031304362
-
Molecular imaging of biological samples: Localization of peptides and proteins using MALDI-TOF MS
-
Caprioli RM, Farmer TB, Gile J. Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS. Anal. Chem. 69(23), 4751-4760 (1997
-
(1997)
Anal. Chem
, vol.69
, Issue.23
, pp. 4751-4760
-
-
Caprioli, R.M.1
Farmer, T.B.2
Gile, J.3
-
5
-
-
33846798240
-
Time-of-flight secondary-ion mass spectrometry for the surface characterization of solid-state pharmaceuticals
-
Prestidge CA, Barnes TJ, Skinner W. Time-of-flight secondary-ion mass spectrometry for the surface characterization of solid-state pharmaceuticals. J. Pharm. Pharmacol. 59(2), 251-259 (2007
-
(2007)
J. Pharm. Pharmacol
, vol.59
, Issue.2
, pp. 251-259
-
-
Prestidge, C.A.1
Barnes, T.J.2
Skinner, W.3
-
6
-
-
5644249240
-
Mass spectrometry sampling under ambient conditions with desorption electrospray ionization
-
Takats Z, Wiseman JM, Gologan B, Cooks RG. Mass spectrometry sampling under ambient conditions with desorption electrospray ionization. Science 306(5695), 471-473 (2004
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 471-473
-
-
Takats, Z.1
Wiseman, J.M.2
Gologan, B.3
Cooks, R.G.4
-
7
-
-
81555215472
-
Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: The terfenadine example
-
Eikel D, Vavrek M, Smith S, et al. Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example. Rapid Commun. Mass Spectrom. 25(23), 3587-3596 (2011
-
(2011)
Rapid Commun. Mass Spectrom
, vol.25
, Issue.23
, pp. 3587-3596
-
-
Eikel, D.1
Vavrek, M.2
Smith, S.3
-
8
-
-
84906260278
-
Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis
-
Swales JG, Tucker JW, Strittmatter N, et al. Mass spectrometry imaging of cassette-dosed drugs for higher throughput pharmacokinetic and biodistribution analysis. Anal. Chem. 86(16), 8473-8480 (2014
-
(2014)
Anal. Chem
, vol.86
, Issue.16
, pp. 8473-8480
-
-
Swales, J.G.1
Tucker, J.W.2
Strittmatter, N.3
-
9
-
-
33748160055
-
Ion formation mechanisms in uv-maldi
-
Knochenmuss R. Ion formation mechanisms in UV-MALDI. Analyst 131(9), 966-986 (2006
-
(2006)
Analyst
, vol.131
, Issue.9
, pp. 966-986
-
-
Knochenmuss, R.1
-
10
-
-
84890523368
-
Mass spectrometry imaging, an emerging technology in neuropsychopharmacology
-
Shariatgorji M, Svenningsson P, Andren PE. Mass spectrometry imaging, an emerging technology in neuropsychopharmacology. Neuropsychopharmacology 39(1), 34-49 (2014
-
(2014)
Neuropsychopharmacology
, vol.39
, Issue.1
, pp. 34-49
-
-
Shariatgorji, M.1
Svenningsson, P.2
Andren, P.E.3
-
11
-
-
34547881888
-
Profiling and imaging of tissues by imaging ion mobility-mass spectrometry
-
Mclean JA, Ridenour WB, Caprioli RM. Profiling and imaging of tissues by imaging ion mobility-mass spectrometry. J. Mass Spectrom. 42(8), 1099-1105 (2007
-
(2007)
J. Mass Spectrom
, vol.42
, Issue.8
, pp. 1099-1105
-
-
Mclean, J.A.1
Ridenour, W.B.2
Caprioli, R.M.3
-
12
-
-
0036209284
-
Investigation of drift gas selectivity in high resolution ion mobility spectrometry with mass spectrometry detection
-
Matz LM, Hill HH Jr, Beegle LW, Kanik I. Investigation of drift gas selectivity in high resolution ion mobility spectrometry with mass spectrometry detection. J. Am. Soc. Mass Spectrom. 13(4), 300-307 (2002
-
(2002)
J. Am. Soc. Mass Spectrom
, vol.13
, Issue.4
, pp. 300-307
-
-
Matz, L.M.1
Hill, H.H.2
Beegle, L.W.3
Kanik, I.4
-
13
-
-
84856731515
-
The significance of ambient-temperature on pharmaceutical and endogenous compound abundance and distribution in tissues sections when analyzed by matrix-assisted laser desorption/ionization mass spectrometry imaging
-
Goodwin RJ, Iverson SL, Andren PE. The significance of ambient-temperature on pharmaceutical and endogenous compound abundance and distribution in tissues sections when analyzed by matrix-assisted laser desorption/ionization mass spectrometry imaging. Rapid Commun. Mass Spectrom. 26(5), 494-498 (2012
-
(2012)
Rapid Commun. Mass Spectrom
, vol.26
, Issue.5
, pp. 494-498
-
-
Goodwin, R.J.1
Iverson, S.L.2
Andren, P.E.3
-
14
-
-
84865157702
-
Sample preparation for mass spectrometry imaging: Small mistakes can lead to big consequences
-
Goodwin RJ. Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences. J. Proteomics 75(16), 4893-4911 (2012
-
(2012)
J. Proteomics
, vol.75
, Issue.16
, pp. 4893-4911
-
-
Goodwin, R.J.1
-
15
-
-
61849162815
-
Heat stabilization of the tissue proteome: A new technology for improved proteomics
-
Svensson M, Boren M, Skold K, et al. Heat stabilization of the tissue proteome: a new technology for improved proteomics. J. Proteome Res. 8(2), 974-981 (2009
-
(2009)
J. Proteome Res
, vol.8
, Issue.2
, pp. 974-981
-
-
Svensson, M.1
Boren, M.2
Skold, K.3
-
16
-
-
84865185551
-
Conductive carbon tape used for support and mounting of both whole animal and fragile heat-treated tissue sections for maldi ms imaging and quantitation
-
Goodwin RJ, Nilsson A, Borg D, et al. Conductive carbon tape used for support and mounting of both whole animal and fragile heat-treated tissue sections for MALDI MS imaging and quantitation. J. Proteomics 75(16), 4912-4920 (2012
-
(2012)
J. Proteomics
, vol.75
, Issue.16
, pp. 4912-4920
-
-
Goodwin, R.J.1
Nilsson, A.2
Borg, D.3
-
17
-
-
25144493577
-
Maldi-ms imaging of features smaller than the size of the laser beam
-
Jurchen JC, Rubakhin SS, Sweedler JV. MALDI-MS imaging of features smaller than the size of the laser beam. J. Am. Soc. Mass Spectrom. 16(10), 1654-1659 (2005
-
(2005)
J. Am. Soc. Mass Spectrom
, vol.16
, Issue.10
, pp. 1654-1659
-
-
Jurchen, J.C.1
Rubakhin, S.S.2
Sweedler, J.V.3
-
18
-
-
84861168071
-
Controlledph tissue cleanup protocol for signal enhancement of small molecule drugs analyzed by maldi-ms imaging
-
Shariatgorji M, Kallback P, Gustavsson L, et al. ControlledpH tissue cleanup protocol for signal enhancement of small molecule drugs analyzed by MALDI-MS imaging. Anal. Chem. 84(10), 4603-4607 (2012
-
(2012)
Anal. Chem
, vol.84
, Issue.10
, pp. 4603-4607
-
-
Shariatgorji, M.1
Kallback, P.2
Gustavsson, L.3
-
19
-
-
80053645952
-
On-tissue chemical derivatization of 3-methoxysalicylamine for maldi-imaging mass spectrometry
-
Chacon A, Zagol-Ikapitte I, Amarnath V, et al. On-tissue chemical derivatization of 3-methoxysalicylamine for MALDI-imaging mass spectrometry. J. Mass Spectrom. 46(8), 840-846 (2011
-
(2011)
J. Mass Spectrom
, vol.46
, Issue.8
, pp. 840-846
-
-
Chacon, A.1
Zagol-Ikapitte, I.2
Amarnath, V.3
-
20
-
-
84918820975
-
Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections
-
Shariatgorji M, Nilsson A, Goodwin RJ, et al. Direct targeted quantitative molecular imaging of neurotransmitters in brain tissue sections. Neuron 84(4), 697-707 (2014
-
(2014)
Neuron
, vol.84
, Issue.4
, pp. 697-707
-
-
Shariatgorji, M.1
Nilsson, A.2
Goodwin, R.J.3
-
21
-
-
84929088313
-
Pyrylium salts as reactive matrices for maldi-ms imaging of biologically active primary amines
-
Shariatgorji M, Nilsson A, Kallback P, et al. Pyrylium salts as reactive matrices for MALDI-MS imaging of biologically active primary amines. J. Am. Soc. Mass Spectrom. 26(6), 934-939 (2015
-
(2015)
J. Am. Soc. Mass Spectrom
, vol.26
, Issue.6
, pp. 934-939
-
-
Shariatgorji, M.1
Nilsson, A.2
Kallback, P.3
-
22
-
-
84865185525
-
Novel mass spectrometry imaging software assisting labeled normalization and quantitation of drugs and neuropeptides directly in tissue sections
-
Kallback P, Shariatgorji M, Nilsson A, Andren PE. Novel mass spectrometry imaging software assisting labeled normalization and quantitation of drugs and neuropeptides directly in tissue sections. J. Proteomics 75(16), 4941-4951 (2012
-
(2012)
J. Proteomics
, vol.75
, Issue.16
, pp. 4941-4951
-
-
Kallback, P.1
Shariatgorji, M.2
Nilsson, A.3
Andren, P.E.4
-
23
-
-
33846012228
-
Compound and metabolite distribution measured by MALDI mass spectrometric imaging in whole-body tissue sections
-
Stoeckli M, Staab D, Schweitzer A. Compound and metabolite distribution measured by MALDI mass spectrometric imaging in whole-body tissue sections. Int. J. Mass Spectrom. 260(2-3), 195-202 (2007
-
(2007)
Int. J. Mass Spectrom
, vol.260
, Issue.2-3
, pp. 195-202
-
-
Stoeckli, M.1
Staab, D.2
Schweitzer, A.3
-
24
-
-
84865169841
-
Quantitative mass spectrometry imaging of propranolol and olanzapine using tissue extinction calculation as normalization factor
-
Hamm G, Bonnel D, Legouffe R, et al. Quantitative mass spectrometry imaging of propranolol and olanzapine using tissue extinction calculation as normalization factor. J. Proteomics 75(16), 4952-4961 (2012
-
(2012)
J. Proteomics
, vol.75
, Issue.16
, pp. 4952-4961
-
-
Hamm, G.1
Bonnel, D.2
Legouffe, R.3
-
25
-
-
84913587083
-
Label-free MS imaging from drug discovery to preclinical development
-
Hochart G, Hamm G, Stauber J. Label-free MS imaging from drug discovery to preclinical development. Bioanalysis 6(20), 2775-2788 (2014
-
(2014)
Bioanalysis
, vol.6
, Issue.20
, pp. 2775-2788
-
-
Hochart, G.1
Hamm, G.2
Stauber, J.3
-
26
-
-
77955372862
-
Fine mapping the spatial distribution and concentration of unlabeled drugs within tissue micro-compartments using imaging mass spectrometry
-
Nilsson A, Fehniger TE, Gustavsson L, et al. Fine mapping the spatial distribution and concentration of unlabeled drugs within tissue micro-compartments using imaging mass spectrometry. PLoS ONE 5(7), e11411 (2010
-
(2010)
Plos One
, vol.5
, Issue.7
, pp. e11411
-
-
Nilsson, A.1
Fehniger, T.E.2
Gustavsson, L.3
-
27
-
-
84872586328
-
Quantitative maldi tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard
-
Pirman DA, Reich RF, Kiss A, Heeren RMA, Yost RA. Quantitative MALDI tandem mass spectrometric imaging of cocaine from brain tissue with a deuterated internal standard. Anal. Chem. 85(2), 1081-1089 (2013
-
(2013)
Anal. Chem
, vol.85
, Issue.2
, pp. 1081-1089
-
-
Pirman, D.A.1
Reich, R.F.2
Kiss, A.3
Heeren, R.M.A.4
Yost, R.A.5
-
28
-
-
79952138038
-
Drug and metabolite concentrations in tissues in relationship to tissue adverse findings: A review
-
Pellegatti M, Pagliarusco S. Drug and metabolite concentrations in tissues in relationship to tissue adverse findings: a review. Expert Opin. Drug Metabol. Toxicol. 7(2), 137-146 (2011
-
(2011)
Expert Opin. Drug Metabol. Toxicol
, vol.7
, Issue.2
, pp. 137-146
-
-
Pellegatti, M.1
Pagliarusco, S.2
-
29
-
-
84867886333
-
In situ mass spectrometry imaging and ex vivo characterization of renal crystalline deposits induced in multiple preclinical drug toxicology studies
-
Nilsson A, Forngren B, Bjurstrom S, et al. In situ mass spectrometry imaging and ex vivo characterization of renal crystalline deposits induced in multiple preclinical drug toxicology studies. PLoS ONE 7(10), e47353 (2012
-
(2012)
Plos One
, vol.7
, Issue.10
, pp. e47353
-
-
Nilsson, A.1
Forngren, B.2
Bjurstrom, S.3
-
30
-
-
33748865022
-
Direct molecular analysis of wholebody animal tissue sections by imaging MALDI mass spectrometry
-
Khatib-Shahidi S, Andersson M, Herman JL, Gillespie TA, Caprioli RM. Direct molecular analysis of wholebody animal tissue sections by imaging MALDI mass spectrometry. Anal. Chem. 78(18), 6448-6456 (2006
-
(2006)
Anal. Chem
, vol.78
, Issue.18
, pp. 6448-6456
-
-
Khatib-Shahidi, S.1
Andersson, M.2
Herman, J.L.3
Gillespie, T.A.4
Caprioli, R.M.5
-
31
-
-
83655172683
-
Qualitative and quantitative maldi imaging of the positron emission tomography ligands raclopride (a d2 dopamine antagonist) and sch 23390 (a d1 dopamine antagonist) in rat brain tissue sections using a solvent-free dry matrix application method
-
Goodwin RJ, Mackay CL, Nilsson A, et al. Qualitative and quantitative MALDI imaging of the positron emission tomography ligands raclopride (a D2 dopamine antagonist) and SCH 23390 (a D1 dopamine antagonist) in rat brain tissue sections using a solvent-free dry matrix application method. Anal. Chem. 83(24), 9694-9701 (2011
-
(2011)
Anal. Chem
, vol.83
, Issue.24
, pp. 9694-9701
-
-
Goodwin, R.J.1
Mackay, C.L.2
Nilsson, A.3
-
32
-
-
66149130750
-
Differential receptormediated drug targeting to the diseased brain
-
Rip J, Schenk GJ, De Boer AG. Differential receptormediated drug targeting to the diseased brain. Expert Opin. Drug Deliv. 6(3), 227-237 (2009
-
(2009)
Expert Opin. Drug Deliv
, vol.6
, Issue.3
, pp. 227-237
-
-
Rip, J.1
Schenk, G.J.2
De Boer, A.G.3
-
33
-
-
84885162748
-
Molecular imaging of drug transit through the blood-brain barrier with maldi mass spectrometry imaging
-
Liu X, Ide JL, Norton I, et al. Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging. Sci. Rep. 3, 2859 (2013
-
(2013)
Sci. Rep
, vol.3
, pp. 2859
-
-
Liu, X.1
Ide, J.L.2
Norton, I.3
-
34
-
-
84868573143
-
Drug transport across the blood-brain barrier
-
Pardridge WM. Drug transport across the blood-brain barrier. J. Cereb. Blood Flow Metabol. 32(11), 1959-1972 (2012
-
(2012)
J. Cereb. Blood Flow Metabol
, vol.32
, Issue.11
, pp. 1959-1972
-
-
Pardridge, W.M.1
-
35
-
-
0042899083
-
Blood-brain barrier drug targeting: The future of brain drug development
-
151
-
Pardridge WM. Blood-brain barrier drug targeting: the future of brain drug development. Mol. Interv. 3(2), 90-105, 151 (2003
-
(2003)
Mol. Interv
, vol.3
, Issue.2
, pp. 90-105
-
-
Pardridge, W.M.1
-
36
-
-
84874028596
-
Central nervous system disposition and metabolism of fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase inhibitor: An LC-MS and matrix-assisted laser desorption/ionization imaging MS investigation into central nervous system toxicity
-
Castellino S, Groseclose MR, Sigafoos J, et al. Central nervous system disposition and metabolism of fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase inhibitor: an LC-MS and matrix-assisted laser desorption/ionization imaging MS investigation into central nervous system toxicity. Chem. Res. Toxicol. 26(2), 241-251 (2013
-
(2013)
Chem. Res. Toxicol
, vol.26
, Issue.2
, pp. 241-251
-
-
Castellino, S.1
Groseclose, M.R.2
Sigafoos, J.3
-
37
-
-
84903202263
-
Distribution of the phosphatidylinositol 3-kinase inhibitors pictilisib (gdc-0941) and gne-317 in u87 and gs2 intracranial glioblastoma models-assessment by matrix-assisted laser desorption ionization imaging
-
Salphati L, Shahidi-Latham S, Quiason C, et al. Distribution of the phosphatidylinositol 3-kinase inhibitors pictilisib (GDC-0941) and GNE-317 in U87 and GS2 intracranial glioblastoma models-assessment by matrix-assisted laser desorption ionization imaging. Drug Metabol. Dispos. 42(7), 1110-1116 (2014
-
(2014)
Drug Metabol. Dispos
, vol.42
, Issue.7
, pp. 1110-1116
-
-
Salphati, L.1
Shahidi-Latham, S.2
Quiason, C.3
|