Secretome analysis of lipid-induced insulin resistance in skeletal muscle cells by a combined experimental and bioinformatics workflow

Journal of Proteome Research

Volumn 14, Issue 11, 2015, Pages 4885-4895

  Deshmukh, Atul S ^a,b   Cox, Juergen ^a   Jensen, Lars Juhl ^b   Meissner, Felix ^a   Mann, Matthias ^a,b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b University of Copenhagen   (Denmark)

Author keywords

diabetes; glucose uptake; insulin signaling; mass spectrometry; metabolism; myokines; obesity; palmitic acid; quantitative proteomics; secretome

Indexed keywords

CHEMOKINE; CYTOKINE; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; LIPID; METALLOPROTEINASE; SIGNAL PEPTIDE; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN; BOVINE SERUM ALBUMIN; GLUCOSE; INSULIN; PALMITIC ACID;

ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; INSULIN RESISTANCE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUSCLE CELL; MYOBLAST; MYOTUBE; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN STRUCTURE; PROTEOMICS; SKELETAL MUSCLE; SKELETAL MUSCLE CELL; TANDEM MASS SPECTROMETRY; AMINO ACID SEQUENCE; ANIMAL; BIOLOGY; CELL DIFFERENTIATION; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR GENETICS; MOUSE; PROCEDURES; PROTEIN TERTIARY STRUCTURE; SECRETION (PROCESS);

AMINO ACID SEQUENCE; ANIMALS; CELL DIFFERENTIATION; CELL LINE; COMPUTATIONAL BIOLOGY; CYTOKINES; GENE EXPRESSION REGULATION; GLUCOSE; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; METALLOPROTEASES; MICE; MOLECULAR SEQUENCE DATA; MUSCLE FIBERS, SKELETAL; MYOBLASTS; PALMITIC ACID; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; SERUM ALBUMIN, BOVINE;

EID: 84946854689     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00720     Document Type: Article

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