MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation

Journal of Clinical Investigation

Volumn 125, Issue 11, 2015, Pages 4149-4159

  Ying, Wei ^a   Tseng, Alexander ^b   Chang, Richard Cheng An ^c   Morin, Andrew ^c   Brehm, Tyler ^a   Triff, Karen ^a   Nair, Vijayalekshmi ^c   Zhuang, Guoqing ^c   Song, Hui ^d   Kanameni, Srikanth ^c   Wang, Haiqing ^c   Golding, Michael C ^c   Bazer, Fuller W ^a   Chapkin, Robert S ^a   Safe, Stephen ^c   Zhou, Beiyan ^c  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A M COLLEGE OF MEDICINE   (United States)

^c Department of Veterinary Physiology and Pharmacology   (United States)

^d WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INTERLEUKIN 4; MICRORNA 223; NFAT5 PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PKNOX1 PROTEIN; PROTEIN; RASA1 PROTEIN; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 3' UNTRANSLATED REGION; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HOMEODOMAIN PROTEIN; MICRORNA; MIRN223 MICRORNA, MOUSE; NFAT5 PROTEIN, MOUSE; PIOGLITAZONE; PKNOX1 PROTEIN, MOUSE; PROTEIN BINDING; RASA1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIET INDUCED OBESITY; ENHANCER REGION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; INSULIN BLOOD LEVEL; INSULIN TOLERANCE TEST; INTRAABDOMINAL FAT; LIPID DIET; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; 3' UNTRANSLATED REGION; ADIPOCYTE; ADVERSE EFFECTS; ANIMAL; BIOSYNTHESIS; BONE MARROW; C57BL MOUSE; CHROMATIN IMMUNOPRECIPITATION; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INFLAMMATION; INSULIN RESISTANCE; KNOCKOUT MOUSE; MALE; PATHOLOGY; PHYSIOLOGY; REPORTER GENE; STROMA CELL; TH2 CELL;

3' UNTRANSLATED REGIONS; ADIPOCYTES; ANIMALS; BONE MARROW; CHROMATIN IMMUNOPRECIPITATION; DIET, HIGH-FAT; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, REPORTER; HOMEODOMAIN PROTEINS; INFLAMMATION; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; MACROPHAGE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRORNAS; P120 GTPASE ACTIVATING PROTEIN; PPAR GAMMA; PROTEIN BINDING; STROMAL CELLS; TH2 CELLS; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS;

EID: 84946779883     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI81656     Document Type: Article

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