In vivo study of the mucus-permeating properties of PEG-coated nanoparticles following oral administration

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 97, Issue , 2015, Pages 280-289

  Inchaurraga, Laura ^a   Martín Arbella, Nekane ^a   Zabaleta, Virginia ^a   Quincoces, Gemma ^b   Peñuelas, Ivan ^b   Irache, Juan M ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Mucosa; Mucus; Nanoparticles; Oral; Poly(ethyleneglycol); Poly(methyl vinyl ether co maleic anhydride)

Indexed keywords

GANTREZ COPOLYMER; MACROGOL; NANOPARTICLE; TECHNETIUM 99M; DRUG CARRIER; MACROGOL DERIVATIVE; MALEIC ACID DERIVATIVE; POLY(METHYL VINYL ETHER-CO-MALEIC ANHYDRIDE); POLYETHYLENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG COATING; DRUG PENETRATION; FLUORESCENCE MICROSCOPY; GASTRIC MUCOSA; IN VIVO STUDY; INTESTINE EPITHELIUM; INTESTINE MUCOSA; MALE; MOLECULAR WEIGHT; MUCUS; NONHUMAN; PARTICLE SIZE; RAT; ZETA POTENTIAL; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; METABOLISM; ORAL DRUG ADMINISTRATION; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; DRUG CARRIERS; GASTRIC MUCOSA; INTESTINAL MUCOSA; MALE; MALEATES; MICROSCOPY, FLUORESCENCE; MUCUS; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYETHYLENES; RATS; RATS, WISTAR;

EID: 84946706489     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.12.021     Document Type: Article

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