Molecular imaging techniques to study the biodistribution of orally administered 99mTc-labelled naive and ligand-tagged nanoparticles

Molecular Imaging and Biology

Volumn 13, Issue 6, 2011, Pages 1215-1223

  Areses, Paloma ^a   Agüeros, M Teresa ^b   Quincoces, Gemma ^a   Collantes, María ^c   Richter, José Ángel ^a   López Sánchez, Luisa M ^a   Sánchez Martínez, María ^a   Irache, Juan M ^b   Penuelas, Iván ^a,c  

^a UNIVERSITY CLINIC OF NAVARRA   (Spain)

^b UNIVERSITY OF NAVARRA   (Spain)

^c UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Biodistribution; Cyclodextrins; Nanoparticles

Indexed keywords

CYCLODEXTRIN; NANOPARTICLE; POLYANHYDRIDE; TECHNETIUM 99M;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISPERSION; DOSE RESPONSE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG LABELING; DRUG PURITY; DRUG STRUCTURE; IN VIVO STUDY; ISOTOPE LABELING; LIGAND BINDING; MALE; MOLECULAR IMAGING; NANOANALYSIS; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ADMINISTRATION, ORAL; ANIMALS; CYCLODEXTRINS; FREEZE DRYING; GASTRIC EMPTYING; LIGANDS; MALE; MOLECULAR IMAGING; NANOPARTICLES; QUALITY CONTROL; RATS; RATS, WISTAR; SPECTRUM ANALYSIS; TECHNETIUM; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

ANIMALIA;

EID: 84855469517     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-010-0456-0     Document Type: Article

References (20)

1. Amidon GL, Lennernas H, Shah VP, Crison JR (1995) A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res 12:413-420
2. Longer MA, Ch'Ng HS, Robinson JR (1985) Bioadhesive polymers as platforms for oral controlled drug delivery III: Oral delivery of chlorothiazide using a bioadhesive polymer. J Pharm Sci 74(4):406-411 (Pubitemid 15112930)
3. Yoo HS, Lee KH, Oh JE, Park TG (2000) In vitro and in vivo antitumor activities of nanoparticles based on doxorubicin-PLGA conjugates. J Control Release 68(3):419-431
4. Ponchel G, Irache J (1998) Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract. Adv Drug Deliv Rev 34:191-219 (Pubitemid 28535112)
5. Arbos P, Wirth M, Arangoa MA, Gabor F, Irache JM (2002) Gantrez AN as a new polymer for the preparation of ligand-nanoparticle conjugates. J Control Release 83(3):321-330 (Pubitemid 35223255)
6. Arbos P, Campanero MA, Arangoa MA, Renedo MJ, Irache JM (2003) Influence of the surface characteristics of PVM/MA nanoparticles on their bioadhesive properties. J Control Release 89(1):19-30 (Pubitemid 36412111)
7. Salman HH, Gamazo C, Campanero MA, Irache JM (2005) Salmonellalike bioadhesive nanoparticles. J Control Release 106:1-13
8. Salman H, Gamazo C, Agüeros M, Irache JM (2007) Bioadhesive capacity and immunoadjuvant properties of thiamine-coated nanoparticles. Vaccine 25:8123-8132 (Pubitemid 350046324)
9. Agüeros M, Areses P, Campanero MA et al (2009) Bioadhesive properties and biodistribution of cyclodextrin-poly(anhydride) nanoparticles. Eur J Pharm Sci 37:231-240
10. Agüeros M, Campanero MA, Irache JM (2005) Simultaneous quantification of different cyclodextrins and Gantrez by HPLC with evaporative light scattering detection. J Pharm Biomed Anal 39:495-502 (Pubitemid 41196054)
11. Duchene D, Ponchel G, Wouessidjewe D (1999) Cyclodextrins in targeting. Application to nanoparticles. Adv Drug Deliv Rev 36(1):29-40
12. Agüeros M, Ruiz-Gatón L, Vauthier C, Bouchemal K, Espuelas S, Ponchel G, Irache JM (2009) Combined hydroxypropyl-ß-cyclodextrin and poly(anhydride) nanoparticles improves the oral permeability of paclitaxel. Eur J Pharm Sci 38:405-413
13. Agüeros M, Zabaleta V, Espuelas S, Campanero MA, Irache JM (2010) Increased oral bioavailability of paclitaxel by its encapsulation through complex formation with cyclodextrins in poly(anhydride) nanoparticles. J Control Release 145:2-8
14. Akiyama Y (1995) In vitro and in vivo evaluation of mucoadhesive microspheres prepared for the gastrointestinal tract using polyglycerol esters of fatty acids and a poly(acrylic acid) derivative. Pharm Res 12 (3):397
15. Sakuma S, Sudo R, Suzuki N, Kikuchi H, Akashi M, Hayashi M (1999) Mucoadhesion of polystyrene nanoparticles having surface hydrophilic polymeric chains in the gastrointestinal tract. Int J Pharm 177(2):161-172 (Pubitemid 29073412)
16. Park SH, Gwon HJ, Shin J (2006) Synthesis of 99mTc-labeled organogermanium nanoparticles and their in vivo study as a spleen imaging agent. J Labelled Compd Radiopharmaceut 49(13):1163-1170 (Pubitemid 44913060)
17. Banerjee T, Singh A, Sharma R, Maitra A (2005) Labeling efficiency and biodistribution of technetium-99m labeled nanoparticles: Interference by colloidal tin oxide particles. Int J Pharm 289:189-195 (Pubitemid 40093553)
18. Nemmar A, Vanbilloen H, Hoylaerts M, Hoet P, Verbruggen A, Nemery B (2001) Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster. Am J Respir Crit Care Med 164(9):1665-1668 (Pubitemid 33124156)
19. Eger EI 2nd (1981) Isoflurane: A review. Anesthesiology 55(5):559-576
20. Torjman MC, Joseph JI, Munsick C, Morishita M, Grunwald Z (2005) Effects of isoflurane on gastrointestinal motility after brief exposure in rats. Int J Pharm 294(1-2):65-71 (Pubitemid 40462323)