Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Zhang, Shuang ^a,b   Yu, Min ^a,b   Guo, Qiang ^a,c   Li, Rongpeng ^a,d   Li, Guobo ^b   Tan, Shirui ^a,e   Li, Xuefeng ^a,b   Wei, Yuquan ^b   Wu, Min ^a  

^a UNIVERSITY OF NORTH DAKOTA   (United States)

^b SICHUAN UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d NANJING TECH UNIVERSITY   (China)

^e YUNNAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AUTACOID; CYTOKINE; INTERLEUKIN RECEPTOR; LIPOCORTIN 2; LIPOPOLYSACCHARIDE; PROTEIN BINDING; TICAM-1 PROTEIN, MOUSE; TIRP PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 4; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL; C57BL MOUSE; CELL CULTURE; CONFOCAL MICROSCOPY; DRUG EFFECTS; ENDOSOME; FEMALE; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOBLOTTING; IMMUNOLOGY; KLEBSIELLA INFECTION; KLEBSIELLA PNEUMONIAE; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PHYSIOLOGY; PNEUMONIA; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANNEXIN A2; CELLS, CULTURED; CYTOKINES; ENDOSOMES; FEMALE; HOST-PATHOGEN INTERACTIONS; IMMUNOBLOTTING; INFLAMMATION MEDIATORS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; PHAGOCYTOSIS; PNEUMONIA; PROTEIN BINDING; RECEPTORS, INTERLEUKIN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84946607022     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep15859     Document Type: Article

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