Both RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode

Virology

Volumn 487, Issue , 2016, Pages 230-241

  Akhrymuk, Ivan ^a   Frolov, Ilya ^a   Frolova, Elena I ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

Alphaviruses; Innate immunity; MDA5; Pattern recognition receptors; RIG I; Type I interferon; Virus host interactions

Indexed keywords

BETA INTERFERON; PATTERN RECOGNITION RECEPTOR; PROTEIN MDA5; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; VIRUS PROTEIN; DDX58 PROTEIN, MOUSE; DEAD BOX PROTEIN; IFIH1 PROTEIN, MOUSE; INTERFERON INDUCED HELICASE C DOMAIN CONTAINING PROTEIN 1;

ALPHAVIRUS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; GENETIC CODE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; VIRAL CLEARANCE; VIRUS DETECTION; VIRUS GENE; VIRUS ISOLATION; VIRUS REPLICATION; 3T3 CELL LINE; ANIMAL; CELL LINE; GENE SILENCING; GENE TARGETING; GENETICS; GROWTH, DEVELOPMENT AND AGING; HAMSTER; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOUSE;

3T3 CELLS; ALPHAVIRUS; ANIMALS; CELL LINE; CRICETINAE; DEAD BOX PROTEIN 58; DEAD-BOX RNA HELICASES; GENE KNOCK-IN TECHNIQUES; GENE KNOCKDOWN TECHNIQUES; IMMUNITY, INNATE; INTERFERON-BETA; INTERFERON-INDUCED HELICASE, IFIH1; MICE; RECEPTORS, PATTERN RECOGNITION; VIRUS REPLICATION;

EID: 84946605688     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2015.09.023     Document Type: Article

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