Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein

Virology

Volumn 399, Issue 1, 2010, Pages 1-10

  Cruz, Catherine C ^a,b   Suthar, Mehul S ^c   Montgomery, Stephanie A ^a,b   Shabman, Reed ^a,b   Simmons, Jason ^a,b   Johnston, Robert E ^a,b   Morrison, Thomas E ^a,b,d   Heise, Mark T ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Alphaviruses; nsP1 mutants; Ross River; Sindbis; Type I IFN induction

Indexed keywords

INTERFERON; INTERFERON REGULATORY FACTOR 3; ISOLEUCINE; NONSTRUCTURAL PROTEIN 1; NONSTRUCTURAL PROTEIN 2; RNA 18S; RNA 28S;

ALPHA VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; RNA SYNTHESIS; ROSS RIVER ALPHA VIRUS; SINDBIS VIRUS; VIRUS MUTATION; VIRUS REPLICATION; VIRUS TRANSCRIPTION; VIRUS VIRULENCE;

ALPHAVIRUS INFECTIONS; ANIMALS; CELL LINE; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; L CELLS (CELL LINE); MICE; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RNA; ROSS RIVER VIRUS; SINDBIS VIRUS; TRANSCRIPTIONAL ACTIVATION; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE FACTORS;

ALPHAVIRUS; ANIMALIA; MOSQUITO-BORNE VIRUSES; ROSS RIVER VIRUS;

EID: 77049087748     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.12.031     Document Type: Article

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