메뉴 건너뛰기




Volumn 5, Issue 4, 2015, Pages 731-736

Peripheral Biomarkers of Parkinson's disease progression and pioglitazone Effects

Author keywords

8 hydroxydeoxyguanosine; 8OHdG; biomarker; cytokine; IL 6; inflammation; interleukin 6; oxidativestress; Parkinsons disease; PGC 1alpha; pioglitazone

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BIOLOGICAL MARKER; ESTROGEN RELATED RECEPTOR ALPHA; INTERLEUKIN 6; PEROXIREDOXIN 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PIOGLITAZONE; PLACEBO; RASAGILINE; SELEGILINE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 8-OXO-7-HYDRODEOXYGUANOSINE; ANTIDIABETIC AGENT; DEOXYGUANOSINE; IL6 PROTEIN, HUMAN; PPARGC1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

EID: 84946603008     PISSN: 18777171     EISSN: 1877718X     Source Type: Journal    
DOI: 10.3233/JPD-150666     Document Type: Article
Times cited : (27)

References (34)
  • 1
    • 0038051345 scopus 로고    scopus 로고
    • Mitochondria, oxidative damage, and inflammation in Parkinson's disease
    • Beal MF, 2003 Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann N Y Acad Sci 991 120 131
    • (2003) Ann N y Acad Sci , vol.991 , pp. 120-131
    • Beal, M.F.1
  • 4
    • 84865045728 scopus 로고    scopus 로고
    • Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson's disease
    • Siddiqui A, Chinta SJ, Mallajosyula JK, Rajagopolan S, Hanson I, Rane A, Melov S, Andersen JK, 2012 Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson's disease. Free Radic Biol Med 53 993 1003
    • (2012) Free Radic Biol Med , vol.53 , pp. 993-1003
    • Siddiqui, A.1    Chinta, S.J.2    Mallajosyula, J.K.3    Rajagopolan, S.4    Hanson, I.5    Rane, A.6    Melov, S.7    Andersen, J.K.8
  • 5
    • 58849090439 scopus 로고    scopus 로고
    • Transcribe to Survive: Transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease
    • Clark J, Simon DK, 2009 Transcribe to Survive: Transcriptional control of antioxidant defense programs for neuroprotection in Parkinson's disease. Antioxid Redox Signal 11 509 528
    • (2009) Antioxid Redox Signal , vol.11 , pp. 509-528
    • Clark, J.1    Simon, D.K.2
  • 6
    • 0032911488 scopus 로고    scopus 로고
    • Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
    • Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ, 1999 Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol 154 1423 1429
    • (1999) Am J Pathol , vol.154 , pp. 1423-1429
    • Zhang, J.1    Perry, G.2    Smith, M.A.3    Robertson, D.4    Olson, S.J.5    Graham, D.G.6    Montine, T.J.7
  • 9
    • 60849129435 scopus 로고    scopus 로고
    • Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease
    • Chen CM, Liu JL, Wu YR, Chen YC, Cheng HS, Cheng ML, Chiu DT, 2009 Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease. Neurobiol Dis 33 429 435
    • (2009) Neurobiol Dis , vol.33 , pp. 429-435
    • Chen, C.M.1    Liu, J.L.2    Wu, Y.R.3    Chen, Y.C.4    Cheng, H.S.5    Cheng, M.L.6    Chiu, D.T.7
  • 10
    • 15244357268 scopus 로고    scopus 로고
    • Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease
    • Sato S, Mizuno Y, Hattori N, 2005 Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease. Neurology 64 1081 1083
    • (2005) Neurology , vol.64 , pp. 1081-1083
    • Sato, S.1    Mizuno, Y.2    Hattori, N.3
  • 11
    • 0030964023 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials
    • Gadient RA, Otten UH, 1997 Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials. Prog Neurobiol 52 379 390
    • (1997) Prog Neurobiol , vol.52 , pp. 379-390
    • Gadient, R.A.1    Otten, U.H.2
  • 12
    • 14744296610 scopus 로고    scopus 로고
    • Inflammatory process in Parkinson's disease: Role for cytokines
    • Nagatsu T, Sawada M, 2005 Inflammatory process in Parkinson's disease: Role for cytokines. Curr Pharm Des 11 999 1016
    • (2005) Curr Pharm des , vol.11 , pp. 999-1016
    • Nagatsu, T.1    Sawada, M.2
  • 14
    • 84867629199 scopus 로고    scopus 로고
    • Non-motor symptoms in patients with Parkinson's disease - Correlations with inflammatory cytokines in serum
    • Lindqvist D, Kaufman E, Brundin L, Hall S, Surova Y, Hansson O, 2012 Non-motor symptoms in patients with Parkinson's disease-correlations with inflammatory cytokines in serum. PLoS One 7 e47387
    • (2012) PLoS One , vol.7 , pp. e47387
    • Lindqvist, D.1    Kaufman, E.2    Brundin, L.3    Hall, S.4    Surova, Y.5    Hansson, O.6
  • 16
    • 69349091599 scopus 로고    scopus 로고
    • PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss
    • Miglio G, Rosa AC, Rattazzi L, Collino M, Lombardi G, Fantozzi R, 2009 PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss. Neurochem Int 55 496 504
    • (2009) Neurochem Int , vol.55 , pp. 496-504
    • Miglio, G.1    Rosa, A.C.2    Rattazzi, L.3    Collino, M.4    Lombardi, G.5    Fantozzi, R.6
  • 17
    • 84872499423 scopus 로고    scopus 로고
    • The effect of hydrochloride pioglitazone on urinary 8-hydroxy -deoxyguanosine excretion in type 2 diabetics
    • Wang Y, Ye S, Hu Y, Zhao L, Zheng M, 2013 The effect of hydrochloride pioglitazone on urinary 8-hydroxy -deoxyguanosine excretion in type 2 diabetics. J Diabetes Complications 27 75 77
    • (2013) J Diabetes Complications , vol.27 , pp. 75-77
    • Wang, Y.1    Ye, S.2    Hu, Y.3    Zhao, L.4    Zheng, M.5
  • 18
    • 70350635644 scopus 로고    scopus 로고
    • Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy
    • Abe H, Mita T, Kudo K, Funayama T, Tokoro M, Kaga H, Ikeda F, Kanazawa A, Hirose T, Kawamori R, Watada H, 2009 Dramatic improvement of blood glucose control after pioglitazone treatment in poorly controlled over-weight diabetic patients with myotonic dystrophy. Endocr J 56 911 913
    • (2009) Endocr J , vol.56 , pp. 911-913
    • Abe, H.1    Mita, T.2    Kudo, K.3    Funayama, T.4    Tokoro, M.5    Kaga, H.6    Ikeda, F.7    Kanazawa, A.8    Hirose, T.9    Kawamori, R.10    Watada, H.11
  • 19
    • 33847093475 scopus 로고    scopus 로고
    • Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats
    • Park SW, Yi JH, Miranpuri G, Satriotomo I, Bowen K, Resnick DK, Vemuganti R, 2007 Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats. J Pharmacol Exp Ther 320 1002 1012
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 1002-1012
    • Park, S.W.1    Yi, J.H.2    Miranpuri, G.3    Satriotomo, I.4    Bowen, K.5    Resnick, D.K.6    Vemuganti, R.7
  • 20
    • 54849409185 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptorsgamma (PPARgamma) differently modulate the interleukin-6 expression in the peri-infarct cortical tissue in the acute and delayed phases of cerebral ischaemia
    • Patzer A, Zhao Y, Stock I, Gohlke P, Herdegen T, Culman J, 2008 Peroxisome proliferator-activated receptorsgamma (PPARgamma) differently modulate the interleukin-6 expression in the peri-infarct cortical tissue in the acute and delayed phases of cerebral ischaemia. Eur J Neurosci 28 1786 1794
    • (2008) Eur J Neurosci , vol.28 , pp. 1786-1794
    • Patzer, A.1    Zhao, Y.2    Stock, I.3    Gohlke, P.4    Herdegen, T.5    Culman, J.6
  • 21
    • 78349268336 scopus 로고    scopus 로고
    • Anti-inflammatory effects of pioglitazone on iron-induced oxidative injury in the nigrostriatal dopaminergic system
    • Yu HC, Feng SF, Chao PL, Lin AM, 2010 Anti-inflammatory effects of pioglitazone on iron-induced oxidative injury in the nigrostriatal dopaminergic system. Neuropathol Appl Neurobiol 36 612 622
    • (2010) Neuropathol Appl Neurobiol , vol.36 , pp. 612-622
    • Yu, H.C.1    Feng, S.F.2    Chao, P.L.3    Lin, A.M.4
  • 22
    • 42949100802 scopus 로고    scopus 로고
    • The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B
    • Quinn LP, Crook B, Hows ME, Vidgeon-Hart M, Chapman H, Upton N, Medhurst AD, Virley DJ, 2008 The PPARgamma agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B. Br J Pharmacol 154 226 233
    • (2008) Br J Pharmacol , vol.154 , pp. 226-233
    • Quinn, L.P.1    Crook, B.2    Hows, M.E.3    Vidgeon-Hart, M.4    Chapman, H.5    Upton, N.6    Medhurst, A.D.7    Virley, D.J.8
  • 23
    • 0036326074 scopus 로고    scopus 로고
    • Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease
    • Breidert T, Callebert J, Heneka MT, Landreth G, Launay JM, Hirsch EC, 2002 Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. J Neurochem 82 615 624
    • (2002) J Neurochem , vol.82 , pp. 615-624
    • Breidert, T.1    Callebert, J.2    Heneka, M.T.3    Landreth, G.4    Launay, J.M.5    Hirsch, E.C.6
  • 24
    • 0347087323 scopus 로고    scopus 로고
    • Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with i kappa B alpha induction and block of NF kappa B and iNOS activation
    • Dehmer T, Heneka MT, Sastre M, Dichgans J, Schulz JB, 2004 Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. J Neurochem 88 494 501
    • (2004) J Neurochem , vol.88 , pp. 494-501
    • Dehmer, T.1    Heneka, M.T.2    Sastre, M.3    Dichgans, J.4    Schulz, J.B.5
  • 26
    • 84937520622 scopus 로고    scopus 로고
    • Pioglitazone in early Parkinson's disease: A phase 2, multicentre, double-blind, randomised trial
    • Ninds Exploratory Trials in Parkinson Disease FS-ZONE, Investigators
    • Ninds Exploratory Trials in Parkinson Disease FS-ZONE, Investigators 2015 Pioglitazone in early Parkinson's disease: A phase 2, multicentre, double-blind, randomised trial. Lancet Neurol 14 795 803
    • (2015) Lancet Neurol , vol.14 , pp. 795-803
  • 30
    • 84938717912 scopus 로고    scopus 로고
    • Glitazone treatment and incidence of Parkinson's disease among people with diabetes: A retrospective cohort study
    • Brauer R, Bhaskaran K, Chaturvedi N, Dexter DT, Smeeth L, Douglas I, 2015 Glitazone treatment and incidence of Parkinson's disease among people with diabetes: A retrospective cohort study. PLoS Med 12 e1001854
    • (2015) PLoS Med , vol.12 , pp. e1001854
    • Brauer, R.1    Bhaskaran, K.2    Chaturvedi, N.3    Dexter, D.T.4    Smeeth, L.5    Douglas, I.6
  • 32
    • 84887083013 scopus 로고    scopus 로고
    • The role of inflammation in sporadic and familial Parkinson's disease
    • Deleidi M, Gasser T, 2013 The role of inflammation in sporadic and familial Parkinson's disease. Cell Mol Life Sci 70 4259 4273
    • (2013) Cell Mol Life Sci , vol.70 , pp. 4259-4273
    • Deleidi, M.1    Gasser, T.2
  • 33
    • 2342430102 scopus 로고    scopus 로고
    • Lower plasma adiponectin concentration predicts the efficacy of pioglitazone in diabetic patients
    • Hiramatsu S, Tajiri Y, Karashima T, 2004 Lower plasma adiponectin concentration predicts the efficacy of pioglitazone in diabetic patients. Diabetes Obes Metab 6 231 233
    • (2004) Diabetes Obes Metab , vol.6 , pp. 231-233
    • Hiramatsu, S.1    Tajiri, Y.2    Karashima, T.3
  • 34
    • 33645083474 scopus 로고    scopus 로고
    • Pioglitazone increases circulating adiponectin levels and subsequently reduces TNF-alpha levels in Type 2 diabetic patients: A randomized study
    • Shimizu H, Oh IS, Tsuchiya T, Ohtani KI, Okada S, Mori M, 2006 Pioglitazone increases circulating adiponectin levels and subsequently reduces TNF-alpha levels in Type 2 diabetic patients: A randomized study. Diabet Med 23 253 257
    • (2006) Diabet Med , vol.23 , pp. 253-257
    • Shimizu, H.1    Oh, I.S.2    Tsuchiya, T.3    Ohtani, K.I.4    Okada, S.5    Mori, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.