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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 23, 2015, Pages 5632-5635

Bioreductive deprotection of 4-nitrobenzyl group on thymine base in oligonucleotides for the activation of duplex formation

(5) Saneyoshi, Hisao a Hiyoshi, Yuki a Iketani, Koichi a Kondo, Kazuhiko a Ono, Akira a

a KANAGAWA UNIVERSITY (Japan)

Author keywords

Hybridization; Hypoxia; Nucleic acid based therapeutics; Prodrug; Protecting group

Indexed keywords

OLIGONUCLEOTIDE; PRODRUG; THYMINE DERIVATIVE; NITROPHENOL; THYMINE;

ARTICLE; DEPROTECTION REACTION; DRUG MECHANISM; DRUG SYNTHESIS; DRUG TARGETING; HYPOXIC CELL; CHEMICAL STRUCTURE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOXIA; OXIDATION REDUCTION REACTION; SYNTHESIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYPOXIA; MOLECULAR STRUCTURE; NITROPHENOLS; OLIGONUCLEOTIDES; OXIDATION-REDUCTION; THYMINE;

EID: 84946600475 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2015.10.025 Document Type: Article

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