Synthesis, in vitro cytotoxicity and radiosensitizing activity of novel 3-[(2,4-dinitrophenylamino)alkyl] derivatives of 5-fluorouracil

Chemical Biology and Drug Design

Volumn 83, Issue 2, 2014, Pages 183-190

  Khalaj, Ali ^a,b   Abdi, Khosrou ^a   Ostad, Seyed Nasser ^a   Khoshayand, Mohammad Reza ^a   Lamei, Navid ^b   Nedaie, Hasan Ali ^c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

2,4 dinitrophenylamine; 5 fluorouracil; HT 29 cell line; Radiosensitizing; Tethered compounds

Indexed keywords

2,4 DINITROPHENOL; 3 [(2,4 DINITROPHENYLAMINO)METHYL] 5 FLUOROPYRIMIDINE 2,4(1H,3H) DIONE; 5 FLOURO 3 [(2 (2,4 DINITROPHENYLAMINO)ETHYL)] PYRIMIDINE 2,4 (1H) DIONE; 5 FLOURO 3 [(3 (2,4 DINITROPHENYLAMINO)PROPYL)] PYRIMIDINE 2,4 (1H) DIONE; 5 FLOURO 3 [(4 (2,4 DINITROPHENYLAMINO)BUTYL)]PYRIMIDINE 2,4 (1H) DIONE; 5 FLOURO 3 [(5 (2,4 DINITROPHENYLAMINO)PENTYL)]PYRIMIDINE 2,4 (1H) DIONE; 5 FLOURO 3 [(6 (2,4 DINITROPHENYLAMINO)HEXYL)]PYRIMIDINE 2,4 (1H) DIONE; FLUOROURACIL DERIVATIVE; HYDROCHLORIC ACID; N (2 BROMOETHYL) 2,4 DINITROBENZENEAMINE; N (6 BROMOHEXYL) 2,4 DINITROBENZENEAMINE; PARAFORMALDEHYDE; UNCLASSIFIED DRUG;

ARTICLE; CELL SURVIVAL; CLONOGENIC ASSAY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; ONE POT SYNTHESIS; PRIORITY JOURNAL; RADIOSENSITIZATION;

2,4-DINITROPHENYLAMINE; 5-FLUOROURACIL; HT-29 CELL LINE; RADIOSENSITIZING; TETHERED COMPOUNDS;

ANILINE COMPOUNDS; CELL HYPOXIA; CELL SURVIVAL; FLUOROURACIL; GAMMA RAYS; HT29 CELLS; HUMANS; RADIATION-SENSITIZING AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84892559202     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12211     Document Type: Article

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