Tetracycline antibiotics impair mitochondrial function and its experimental use confounds research

Cancer Research

Volumn 75, Issue 21, 2015, Pages 4446-4449

  Chatzispyrou, Iliana A ^a   Held, Ntsiki M ^a   Mouchiroud, Laurent ^b   Auwerx, Johan ^b   Houtkooper, Riekelt H ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; TETRACYCLINE DERIVATIVE; ANTIINFECTIVE AGENT; PROTEIN SYNTHESIS INHIBITOR;

ARTICLE; BACTERIUM; CANCER RESEARCH; CELL PROLIFERATION; CELL SURVIVAL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SEQUENCE; HUMAN; LOSS OF FUNCTION MUTATION; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; NEOPLASM; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VOLUME; ANIMAL; DRUG EFFECTS; METABOLISM; MITOCHONDRION; MOUSE; PROTEIN SYNTHESIS;

ANIMALS; ANTI-BACTERIAL AGENTS; DOXYCYCLINE; HUMANS; MICE; MITOCHONDRIA; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS;

EID: 84946593821     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-1626     Document Type: Article

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