Dual small-molecule targeting of SMAD signaling stimulates human induced pluripotent stem cells toward neural lineages

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Wattanapanitch, Methichit ^a   Klincumhom, Nuttha ^a   Potirat, Porntip ^a   Amornpisutt, Rattaya ^a   Lorthongpanich, Chanchao ^a   U Pratya, Yaowalak ^a   Laowtammathron, Chuti ^a   Kheolamai, Pakpoom ^b   Poungvarin, Niphon ^a   Iaragrisil, Surapol ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b THAMMASAT UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; NOGGIN; SMAD PROTEIN; VALPROIC ACID; 1,3 DIOXOLANE DERIVATIVE; 4-(5-BENZO(1,3)DIOXOL-5-YL-4-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; AMIDE; BENZAMIDE DERIVATIVE; BIOLOGICAL MARKER; CARRIER PROTEIN; HISTONE DEACETYLASE; NOGGIN PROTEIN; PYRIDINE DERIVATIVE; RHO KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL STRUCTURE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEURAL STEM CELL; NEUROEPITHELIUM CELL; NONHUMAN; NUCLEAR REPROGRAMMING; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TERATOMA; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CYTOLOGY; DERMIS; DRUG EFFECTS; FIBROBLAST; GENE EXPRESSION; GENETICS; KARYOTYPING; METABOLISM; NERVE CELL; PLURIPOTENT STEM CELL;

AMIDES; BENZAMIDES; BIOMARKERS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELLS, CULTURED; CELLULAR REPROGRAMMING; DERMIS; DIOXOLES; FIBROBLASTS; GENE EXPRESSION; HISTONE DEACETYLASES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KARYOTYPING; NEURAL STEM CELLS; NEURONS; PYRIDINES; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; SMAD PROTEINS; VALPROIC ACID;

EID: 84946585569     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106952     Document Type: Article

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