Chronic iron overload in rats increases vascular reactivity by increasing oxidative stress and reducing nitric oxide bioavailability

Life Sciences

Volumn 143, Issue , 2015, Pages 89-97

  Marques, Vinicius Bermond ^a   Nascimento, Tatiani Botelho ^a   Ribeiro, Rogério Faustino ^a   Broseghini Filho, Gilson Brás ^a   Rossi, Emilly Martinelly ^a   Graceli, Jones Bernades ^a   Dos Santos, Leonardo ^a  

^a FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

Author keywords

Endothelium; Haemochromatosis; Iron; Oxidative stress; Vascular disease

Indexed keywords

ALLOPURINOL; APOCYNIN; CATALASE; DIPEPTIDYL CARBOXYPEPTIDASE; IRON DEXTRAN; LOSARTAN; MALONALDEHYDE; N(G) NITROARGININE METHYL ESTER; NADPH OXIDASE SUBUNIT P22 PHOX; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM CHLORIDE; TIRON; TRANSFERRIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; BLOOD LEVEL; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; CARDIOVASCULAR FUNCTION; CHRONIC DISEASE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; IN VITRO STUDY; IRON BLOOD LEVEL; IRON OVERLOAD; LIPID PEROXIDATION; LIVER; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TRANSFERRIN BLOOD LEVEL; VASCULAR ENDOTHELIUM; VASCULAR RING; VASOCONSTRICTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOAVAILABILITY; METABOLISM; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PHYSIOLOGY; WISTAR RAT;

ANIMALS; BIOLOGICAL AVAILABILITY; CHRONIC DISEASE; ENDOTHELIUM, VASCULAR; IRON OVERLOAD; MALE; NITRIC OXIDE; ORGAN CULTURE TECHNIQUES; OXIDATIVE STRESS; RATS; RATS, WISTAR;

EID: 84946574431     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2015.10.034     Document Type: Article

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