Experimental Renal Failure and Iron Overload: A Histomorphometric Study in Rat Tibia

Toxicologic Pathology

Volumn 33, Issue 3, 2005, Pages 398-403

  Mandalunis, Patricia M ^a   Ubios, Angela M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

adynamic bone disease; bone histomorphometry; bone remodeling; iron overload; Rat tibia; renal failure

Indexed keywords

CREATININE; IRON; IRON DEXTRAN; PARATHYROID HORMONE; TETRACYCLINE DERIVATIVE; UREA;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE METABOLISM; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG INDICATION; EXPERIMENTAL SURGERY; FIBROSIS; HISTOPATHOLOGY; IRON OVERLOAD; KIDNEY FAILURE; MORPHOMETRICS; NEPHRECTOMY; NONHUMAN; OSSIFICATION; PARATHYROID HORMONE BLOOD LEVEL; PRIORITY JOURNAL; RAT; TIBIA; TRABECULAR BONE; UREA BLOOD LEVEL;

ANIMALS; BLOOD UREA NITROGEN; CREATININE; DISEASE MODELS, ANIMAL; HUMANS; IRON; IRON OVERLOAD; KIDNEY FAILURE; MALE; NEPHRECTOMY; PARATHYROID HORMONE; RATS; RATS, WISTAR; TIBIA; TIME FACTORS;

EID: 18144387931     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230590935826     Document Type: Article

References (22)

1. Ackrill P, Day P, Ahmed R Aluminum and iron overload in chronic dialysis Kidney Int 1988 33 163-7
2. Afifi A Renal osteodystrophy in developing countries Artif Organs 2002 26 767-9
3. Cobo A, López J, Carbajo E, Santos F, Alvarez J, Fernández M, Weruaga A Growth plate cartilage formation and resorption are differentially depressed in growth retarded uremic rats J Am Soc Nephrol 1999 10 971-9
4. de Vernejoul MC, Pointillart A, Golenzer CC, Morieux C, Bielakoff J, Modrowski D, Miravet L Effects of iron overload on bone remodeling in pigs Am J Pathol 1984 116 377-84
5. Diamond T, Pojer R, Stiel D, Alfrey A, Posen S Does iron affect osteoblast function? Studies in vitro and in patients with chronic liver disease Calcif Tissue Int 1991 48 373-9
6. Ebina Y, Okada S, Hamazaki S, Toda Y, Midorikawa O Impairment of bone formation with aluminum and ferric nitrilotriacetate complexes Calcif Tissue Int 1991 48 28 36
7. Ellis HA, McCarthy JH, Herrington J Bone aluminium in haemodialysed patients and in rats injected with aluminium chloride: relationship to impaired bone mineralization J Clin Path 1979 32 832-44
8. Gerharz EW, Mosekilde L, Thomsen JS, Gasser JA, Moniz C, Barth PJ, Ransley PG, Woodhouse CR The effect of enterocystoplasty on bone strength assessed at four different skeletal sites in a rat model Bone 2003 33 549-56
9. Habener JF, Potts JT Jr Avioli LV, Krane SM Fundamental considerations in the physiology, biology, and biochemistry of parathyroid hormone Metabolic Bone Disease and Clinically Related Disorders 1990 2 Philadelphia W.B. Saunders Company 69 130
10. Huser H, Gerber L, Eichenberger P, Waelti E, Cottier H Short-lasting accumulation in osteoid bone seams of radioactive iron injected as citrate into mice Am J Pathol 1988 131 339-43
11. Jacob AK, Hotchkiss RS, De Meester SL, Hiramatsu M, Karl IE, Swanson PE, Cobb JP, Bouchman TG Endothelial cell apoptosis is accelerated by inorganic iron and heat via an oxygen radical dependent mechanism Surgery 1997 122 243-53
12. Kaiser L, Schartz KA, Burnatowska-Hledin MA, Mayor GH Microcytic anemia secondary to intraperitoneal aluminium in normal and uremic rats Kidney Int 1984 24 269-74
13. Mahachoklertwattana P, Sirikulchayanonta V, Chuansumrit A, Karnsombat P, Choubtum L, Sriphrapradang A, Domrongkitchaiporn S, Sirisriro R, Rajatanavin R Bone histomorphometry in children and adolescents with β-thalassemia disease: Iron-associated focal osteomalacia J Clin Endocrinol Metab 2003 88 3966-72
14. Malluche HH, Faugere MC Avioli LV, Krane SM Bone biopsies: histology and histomorphometry of bone Metabolic Bone Disease and Clinically Related Disorders 1990 2 Philadelphia W.B. Saunders Company 283 328
15. Mandalunis P, Cabrini RL, Ubios AM Iron overloading inhibits endochondral ossification Acta Odont Latinoamer 1997 10 55 61
16. Mandalunis P, Gibaja F, Ubios AM Experimental renal failure and iron overload: a histomorphometric study in the alveolar bone of rats Exp Toxic Pathol 2002 54 85 90
17. Matsushima S, Torii M, Ozaki K, Narama I Iron lactate-induced osteomalacia in association with osteoblast dynamics Toxicol Pathol 2003 31 646-54
18. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee J Bone Miner Res 1987 2 595 610
19. Pierce-Mykli M, Pierides A Iron and aluminum osteomalacia during hemodialysis. A new syndrome Kidney Int 1984 25 151 Abstr
20. Slatopolsky E, Coburn JW Avioli LV, Krane SM Renal osteodystrophy Metabolic bone disease and clinically related disorders 1990 2 Philadelphia W.B. Saunders Company 452-74
21. Van Landeghem GF, D'Haese PC, Lamberts LV, De Broe ME Competition of iron and aluminum for transferrin: the molecular basis for aluminum deposition in iron overload dialysis patients? Exp Nephrol 1997 5 239-45
22. Velasquez-Forero F, Mondragón A, Herrero B, Pena JC Adynamic bone lesion in renal transplant recipients with normal renal function Nephrol Dial Transplant 1996 3 58 64