Inhibition of mitogen-activated protein kinases/nuclear factor κB-dependent inflammation by a novel chalcone protects the kidney from high fat diet-induced injuries in mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 355, Issue 2, 2015, Pages 235-246

  Fang, Qilu ^a   Deng, Liancheng ^a   Wang, Lintao ^a   Zhang, Yali ^a   Weng, Qiaoyou ^a   Yin, Haimin ^a   Pan, Yong ^a   Tong, Chao ^a   Wang, Jingying ^a   Liang, Guang ^a  

^a WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3,4 IHYDROXYPHENYL) 3 (2 METHOXYPHENYL)PROP 2 EN 1 ONE; ANTIINFLAMMATORY AGENT; CELL ADHESION MOLECULE; CHALCONE; CURCUMIN; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; L 2H17; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 1-(3,4-DIHYDROXYPHENYL)-3-(2-METHOXYPHENYL)PROP-2-EN-1-ONE; CHALCONE DERIVATIVE; FAT INTAKE; HIGH DENSITY LIPOPROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PALMITIC ACID; TRIACYLGLYCEROL; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; INFLAMMATION; KIDNEY DISEASE; KIDNEY INJURY; KIDNEY STRUCTURE; LIPID DIET; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION; ADMINISTRATION AND DOSAGE; ANIMAL; BLOOD; C57BL MOUSE; CELL CULTURE; COMPLICATION; CYTOLOGY; DRUG EFFECTS; FAT INTAKE; KIDNEY; KIDNEY TUBULE; METABOLISM; PATHOLOGY; PERITONEUM MACROPHAGE; RENAL INSUFFICIENCY; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLS, CULTURED; CHALCONES; CYTOKINES; DIET, HIGH-FAT; DIETARY FATS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY; KIDNEY TUBULES; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; MACROPHAGES, PERITONEAL; MALE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; OBESITY; PALMITIC ACID; RENAL INSUFFICIENCY; SIGNAL TRANSDUCTION; TRIGLYCERIDES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84946567180     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.115.226860     Document Type: Article

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