Enzymology of Pyran Ring A Formation in Salinomycin Biosynthesis

Angewandte Chemie - International Edition

Volumn 54, Issue 46, 2015, Pages 13622-13625

  Luhavaya, Hanna ^a   Dias, Marcio V B ^b   Williams, Simon R ^a   Hong, Hui ^a   De Oliveira, Luciana G ^c   Leadlay, Peter F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

biosynthesis; cyclases; dehydratases; polyethers; polyketide synthases

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; ENZYMES; ETHERS; KETONES; METABOLITES; POLYETHERS;

ACTIVE SITE RESIDUES; BIOSYNTHETIC PATHWAY; CATALYTIC VERSATILITY; COMPLEX POLYKETIDE NATURAL PRODUCTS; CYCLASES; DEHYDRATASES; POLYKETIDE SYNTHASES; X RAY CRYSTAL STRUCTURES;

CRYSTAL STRUCTURE;

POLYKETIDE SYNTHASE; PYRAN DERIVATIVE; SALINOMYCIN;

CHEMISTRY; CONFORMATION; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR MODEL; STREPTOMYCES;

MODELS, MOLECULAR; MOLECULAR CONFORMATION; POLYKETIDE SYNTHASES; PYRANS; STREPTOMYCES;

EID: 84946492925     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201507090     Document Type: Article

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