Achieving optimal growth through product feedback inhibition in metabolism

PLoS Computational Biology

Volumn 6, Issue 6, 2010, Pages 1-12

  Goyal, Sidhartha ^a,b   Yuan, Jie ^a   Chen, Thomas ^a   Rabinowitz, Joshua D ^a   Wingreen, Ned S ^a  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; ENZYMES; ESCHERICHIA COLI; FEEDBACK; LAKES; METABOLITES; NUTRIENTS; PHYSIOLOGY;

FEEDBACK INHIBITION; MATHEMATICAL ANALYSIS; METABOLITE POOLS; NUTRIENTS INPUT; OPTIMAL GROWTH; OPTIMALITY; PER UNIT; REGULATORY MECHANISM; SIMPLE++; ULTRASENSITIVE;

METABOLISM;

ALLOSTERISM; ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BIOMASS PRODUCTION; CARBON PARTITIONING; CONTROLLED STUDY; ENZYME MODIFICATION; ESCHERICHIA COLI; HOMEOSTASIS; MATHEMATICAL ANALYSIS; METABOLIC REGULATION; MOLECULAR DYNAMICS; NEGATIVE FEEDBACK; NITROGEN FIXATION; NONHUMAN; NUTRIENT CYCLING; PREDICTION; PROTEIN EXPRESSION; BIOLOGICAL MODEL; BIOMASS; FEEDBACK SYSTEM; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CARBON; NITROGEN;

BIOMASS; CARBON; ESCHERICHIA COLI; FEEDBACK, PHYSIOLOGICAL; MODELS, BIOLOGICAL; NITROGEN; SIGNAL TRANSDUCTION;

EID: 77955501572     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000802     Document Type: Article

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