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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 22, 2015, Pages 5444-5448

Identification of small molecule inhibitors of the STAT3 signaling pathway: Insights into their structural features and mode of action

(11) Kim, Kyeojin a Kim, Su Jung a Han, Young Taek b Hong, Sung Jun a An, Hongchan a Chang, Dong Jo c Kim, Taewoo a Lim, Bumhee a Lee, Jeeyeon a Surh, Young Joon a Suh, Young Ger a

a Seoul National University (South Korea)

b Dankook University (South Korea)

c Sunchon National University (South Korea)

Author keywords

Antitumor; Apoptosis; Breast cancer; Small molecule inhibitors; STAT3

Indexed keywords

ANTINEOPLASTIC AGENT; PROTEIN INHIBITOR; STAT1 PROTEIN; STAT3 PROTEIN; MOLECULAR LIBRARY;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER CELL LINE; BREAST EPITHELIUM CELL; CARCINOGENESIS; CELL DEATH; CELL PROLIFERATION; DESS MARTIN OXIDATION; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG STRUCTURE; ELECTROPHILICITY; HELA CELL LINE; HUMAN; MCF 7 CELL LINE; MOLECULAR DYNAMICS; NUCLEOPHILICITY; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; FEMALE; IMMUNOBLOTTING; MOLECULAR LIBRARY; PHARMACOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; FEMALE; HELA CELLS; HUMANS; IMMUNOBLOTTING; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; STAT3 TRANSCRIPTION FACTOR;

EID: 84946471982 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2015.07.063 Document Type: Article

Times cited : (8)

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