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Volumn 6, Issue , 2015, Pages

A mutational signature in gastric cancer suggests therapeutic strategies

Author keywords

[No Author keywords available]

Indexed keywords

CANCER; DISEASE TREATMENT; GENE EXPRESSION; GENOME; MUTATION;

EID: 84946120134     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9683     Document Type: Article
Times cited : (150)

References (31)
  • 1
    • 17344365851 scopus 로고    scopus 로고
    • Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium
    • Ford, D. et al. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. Am. J. Hum. Genet. 62, 676-689 (1998)
    • (1998) Am. J. Hum. Genet , vol.62 , pp. 676-689
    • Ford, D.1
  • 2
    • 0142178215 scopus 로고    scopus 로고
    • Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2
    • New York Breast Cancer Study Group
    • King, M. C., Marks, J. H. & Mandell, J. B. New York Breast Cancer Study Group. Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science 302, 643-646 (2003)
    • (2003) Science , vol.302 , pp. 643-646
    • King, M.C.1    Marks, J.H.2    Mandell, J.B.3
  • 3
    • 0035098503 scopus 로고    scopus 로고
    • Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer
    • Risch, H. A. et al. Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. Am. J. Hum. Genet. 68, 700-710 (2001)
    • (2001) Am. J. Hum. Genet , vol.68 , pp. 700-710
    • Risch, H.A.1
  • 4
    • 34247537444 scopus 로고    scopus 로고
    • Role of BRCA1 and BRCA2 mutations in pancreatic cancer
    • Greer, J. B. & Whitcomb, D. C. Role of BRCA1 and BRCA2 mutations in pancreatic cancer. Gut 56, 601-605 (2007)
    • (2007) Gut , vol.56 , pp. 601-605
    • Greer, J.B.1    Whitcomb, D.C.2
  • 5
    • 0028960025 scopus 로고
    • Somatic mutations in the BRCA1 gene in sporadic ovarian tumours
    • Merajver, S. D. et al. Somatic mutations in the BRCA1 gene in sporadic ovarian tumours. Nat. Genet. 9, 439-443 (1995)
    • (1995) Nat. Genet , vol.9 , pp. 439-443
    • Merajver, S.D.1
  • 6
    • 0030058209 scopus 로고    scopus 로고
    • Mutation analysis in the BRCA2 gene in primary breast cancers
    • Miki, Y., Katagiri, T., Kasumi, F., Yoshimoto, T. & Nakamura, Y. Mutation analysis in the BRCA2 gene in primary breast cancers. Nat. Genet. 13, 245-247 (1996)
    • (1996) Nat. Genet , vol.13 , pp. 245-247
    • Miki, Y.1    Katagiri, T.2    Kasumi, F.3    Yoshimoto, T.4    Nakamura, Y.5
  • 7
    • 0036261707 scopus 로고    scopus 로고
    • Sensing and repairing DNA double-strand breaks
    • Jackson, S. P. Sensing and repairing DNA double-strand breaks. Carcinogenesis 23, 687-696 (2002)
    • (2002) Carcinogenesis , vol.23 , pp. 687-696
    • Jackson, S.P.1
  • 8
    • 84861541343 scopus 로고    scopus 로고
    • Mutational processes molding the genomes of 21 breast cancers
    • Nik-Zainal, S. et al. Mutational processes molding the genomes of 21 breast cancers. Cell 149, 979-993 (2012)
    • (2012) Cell , vol.149 , pp. 979-993
    • Nik-Zainal, S.1
  • 9
    • 33645084562 scopus 로고    scopus 로고
    • Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer
    • Walsh, T. et al. Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. JAMA 295, 1379-1388 (2006)
    • (2006) JAMA , vol.295 , pp. 1379-1388
    • Walsh, T.1
  • 10
    • 55949092708 scopus 로고    scopus 로고
    • High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
    • Rottenberg, S. et al. High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs. Proc. Natl Acad. Sci. USA 105, 17079-17084 (2008)
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 17079-17084
    • Rottenberg, S.1
  • 11
    • 17244373777 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    • Farmer, H. et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434, 917-921 (2005)
    • (2005) Nature , vol.434 , pp. 917-921
    • Farmer, H.1
  • 12
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Alexandrov, L. B. et al. Signatures of mutational processes in human cancer. Nature 500, 415-421 (2013)
    • (2013) Nature , vol.500 , pp. 415-421
    • Alexandrov, L.B.1
  • 13
    • 84891102589 scopus 로고    scopus 로고
    • Mutational signatures: The patterns of somatic mutations hidden in cancer genomes
    • Alexandrov, L. B. & Stratton, M. R. Mutational signatures: the patterns of somatic mutations hidden in cancer genomes. Curr. Opin. Genet. Dev. 24, 52-60 (2014)
    • (2014) Curr. Opin. Genet. Dev , vol.24 , pp. 52-60
    • Alexandrov, L.B.1    Stratton, M.R.2
  • 14
    • 84906303775 scopus 로고    scopus 로고
    • Mechanisms underlying mutational signatures in human cancers
    • Helleday, T., Eshtad, S. & Nik-Zainal, S. Mechanisms underlying mutational signatures in human cancers. Nat. Rev. Genet. 15, 585-598 (2014)
    • (2014) Nat. Rev. Genet , vol.15 , pp. 585-598
    • Helleday, T.1    Eshtad, S.2    Nik-Zainal, S.3
  • 16
    • 84924056345 scopus 로고    scopus 로고
    • Whole genomes redefine the mutational landscape of pancreatic cancer
    • Waddell, N. et al. Whole genomes redefine the mutational landscape of pancreatic cancer. Nature 518, 495-501 (2015)
    • (2015) Nature , vol.518 , pp. 495-501
    • Waddell, N.1
  • 17
    • 84901680089 scopus 로고    scopus 로고
    • Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer
    • Wang, K. et al. Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. Nat. Genet. 46, 573-582 (2014)
    • (2014) Nat. Genet , vol.46 , pp. 573-582
    • Wang, K.1
  • 18
    • 84860327480 scopus 로고    scopus 로고
    • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
    • Zang, Z. J. et al. Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Nat. Genet. 44, 570-574 (2012)
    • (2012) Nat. Genet , vol.44 , pp. 570-574
    • Zang, Z.J.1
  • 19
    • 82255183148 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
    • Wang, K. et al. Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat. Genet. 43, 1219-1223 (2011)
    • (2011) Nat. Genet , vol.43 , pp. 1219-1223
    • Wang, K.1
  • 20
    • 84907270779 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of gastric adenocarcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 513, 202-209 (2014)
    • (2014) Nature , vol.513 , pp. 202-209
  • 21
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • Ferlay, J. et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127, 2893-2917 (2010)
    • (2010) Int. J. Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1
  • 22
    • 0035173378 scopus 로고    scopus 로고
    • DbSNP: The NCBI database of genetic variation
    • Sherry, S. T. et al. dbSNP: the NCBI database of genetic variation. Nucleic Acids Res. 29, 308-311 (2001)
    • (2001) Nucleic Acids Res , vol.29 , pp. 308-311
    • Sherry, S.T.1
  • 23
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1, 092 human genomes
    • Abecasis, G. R. et al. An integrated map of genetic variation from 1, 092 human genomes. Nature 491, 56-65 (2012)
    • (2012) Nature , vol.491 , pp. 56-65
    • Abecasis, G.R.1
  • 24
    • 84872143942 scopus 로고    scopus 로고
    • Analysis of 6, 515 exomes reveals the recent origin of most human protein-coding variants
    • Fu, W. et al. Analysis of 6, 515 exomes reveals the recent origin of most human protein-coding variants. Nature 493, 216-220 (2013)
    • (2013) Nature , vol.493 , pp. 216-220
    • Fu, W.1
  • 25
    • 84859865967 scopus 로고    scopus 로고
    • The UCSC Genome Browser database: Extensions and updates 2011
    • Dreszer, T. R. et al. The UCSC Genome Browser database: extensions and updates 2011. Nucleic Acids Res. 40, D918-D923 (2012)
    • (2012) Nucleic Acids Res , vol.40 , pp. D918-D923
    • Dreszer, T.R.1
  • 26
    • 84907737648 scopus 로고    scopus 로고
    • Genome sequencing of normal cells reveals developmental lineages and mutational processes
    • Behjati, S. et al. Genome sequencing of normal cells reveals developmental lineages and mutational processes. Nature 513, 422-425 (2014)
    • (2014) Nature , vol.513 , pp. 422-425
    • Behjati, S.1
  • 27
    • 84892699941 scopus 로고    scopus 로고
    • Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
    • Bolli, N. et al. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma. Nat. Commun. 5, 2997 (2014)
    • (2014) Nat. Commun , vol.5 , pp. 2997
    • Bolli, N.1
  • 29
    • 84892928198 scopus 로고    scopus 로고
    • Transmissible [corrected] dog cancer genome reveals the origin and history of an ancient cell lineage
    • Murchison, E. P. et al. Transmissible [corrected] dog cancer genome reveals the origin and history of an ancient cell lineage. Science 343, 437-440 (2014)
    • (2014) Science , vol.343 , pp. 437-440
    • Murchison, E.P.1
  • 30
    • 84899645475 scopus 로고    scopus 로고
    • Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer
    • Nik-Zainal, S. et al. Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer. Nat. Genet. 46, 487-491 (2014)
    • (2014) Nat. Genet , vol.46 , pp. 487-491
    • Nik-Zainal, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.