Dihydrofolate reductase 19-bp deletion polymorphism modifies the association of folate status with memory in a cross-sectional multiethnic study of adults

American Journal of Clinical Nutrition

Volumn 102, Issue 5, 2015, Pages 1279-1288

  Philip, Dana ^a   Buch, Assaf ^a   Moorthy, Denish ^b   Scott, Tammy M ^b   Parnell, Laurence D ^b   Lai, Chao Qiang ^b   Ordovás, José M ^b   Selhub, Jacob ^b   Rosenberg, Irwin H ^b   Tucker, Katherine L ^b,c   Troen, Aron M ^a,b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b TUFTS UNIVERSITY   (United States)

^c UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

Author keywords

Cognition; Dihydrofolate reductase; Folate; Gene nutrient interaction; Memory

Indexed keywords

DIHYDROFOLATE REDUCTASE; FOLIC ACID;

ADULT; AGED; ARTICLE; ATTENTION; CENTER FOR EPIDEMIOLOGICAL STUDIES DEPRESSION SCALE; COGNITION; COGNITION ASSESSMENT; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENZYME POLYMORPHISM; EXECUTIVE FUNCTION; FEMALE; FOLIC ACID BLOOD LEVEL; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC ASSOCIATION; GENOTYPE; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; INDEL MUTATION; MAJOR CLINICAL STUDY; MALE; MEMORY; MINI MENTAL STATE EXAMINATION; PUERTO RICAN; AFRICAN AMERICAN; CAUCASIAN; COHORT ANALYSIS; ENZYMOLOGY; ETHNOLOGY; FOLIC ACID DEFICIENCY; GENETIC ASSOCIATION STUDY; GENETIC POLYMORPHISM; GENETICS; HISPANIC; MASSACHUSETTS; MEMORY DISORDERS; METABOLISM; MIDDLE AGED; NUTRIGENOMICS; NUTRITIONAL STATUS; PATHOPHYSIOLOGY; PREVALENCE; PROCEDURES; PUERTO RICO; VERY ELDERLY;

AFRICAN AMERICANS; AGED; AGED, 80 AND OVER; BOSTON; COHORT STUDIES; CROSS-SECTIONAL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FOLIC ACID; FOLIC ACID DEFICIENCY; GENE DELETION; GENETIC ASSOCIATION STUDIES; HISPANIC AMERICANS; HUMANS; MALE; MEMORY DISORDERS; MIDDLE AGED; NUTRIGENOMICS; NUTRITIONAL STATUS; POLYMORPHISM, GENETIC; PREVALENCE; PUERTO RICO; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84946066187     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.115.111054     Document Type: Article

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