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Volumn 88, Issue 1, 2009, Pages 73-76

The 19-bp deletion of dihydrofolate reductase (DHFR), methylenetetrahydrofolate reductase (MTHFR) C677T, Factor V Leiden, prothrombin G20210A polymorphisms in cancer patients with and without thrombosis

Author keywords

Cancer; DHFR; FVL; MTHFR; PTG20210; Thrombosis

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ANTICOAGULANT AGENT; ANTINEOPLASTIC AGENT; BLOOD CLOTTING FACTOR 5 LEIDEN; DIHYDROFOLATE REDUCTASE; GENOMIC DNA; PROTHROMBIN; TAMOXIFEN;

EID: 57049139443     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-008-0569-6     Document Type: Article
Times cited : (22)

References (15)
  • 1
    • 0028931717 scopus 로고
    • High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance)
    • Rosendaal FR, Koster T, Vandenbroucke JP, Reitsma PH (1995) High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance). Blood 85:1504-1508
    • (1995) Blood , vol.85 , pp. 1504-1508
    • Rosendaal, F.R.1    Koster, T.2    Vandenbroucke, J.P.3    Reitsma, P.H.4
  • 2
    • 12444280066 scopus 로고    scopus 로고
    • A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
    • Poort SR, Rosendaal FR, Reitsma PH, Bertina RM (1996) A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 8:698-703
    • (1996) Blood , vol.8 , pp. 698-703
    • Poort, S.R.1    Rosendaal, F.R.2    Reitsma, P.H.3    Bertina, R.M.4
  • 3
    • 0029049553 scopus 로고
    • A candidate genetic inheritable thrombophilic defect for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, Matthews RG (1995) A candidate genetic inheritable thrombophilic defect for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10:111-113
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3    Goyette, P.4    Sheppard, C.A.5    Matthews, R.G.6
  • 4
    • 0037633079 scopus 로고    scopus 로고
    • Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: Meta-analysis of 31 studies
    • Ray JG, Shmorgun D, Chan WS (2002) Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: Meta-analysis of 31 studies. Pathophysiol Haemost Thromb 32:51-58
    • (2002) Pathophysiol Haemost Thromb , vol.32 , pp. 51-58
    • Ray, J.G.1    Shmorgun, D.2    Chan, W.S.3
  • 5
    • 42249111541 scopus 로고    scopus 로고
    • Prospective study of homocysteine and MTHFR 677TT genotype and risk for venous thrombosis in a general population-results from the HUNT 2 study
    • Naess IA, Chritiansen SC, Romundstad PR, Cannegieter SC, Blom HJ, Rosendaal FR, Hammerstrom J (2008) Prospective study of homocysteine and MTHFR 677TT genotype and risk for venous thrombosis in a general population-results from the HUNT 2 study. Br J Haematol 141: 529-535
    • (2008) Br J Haematol , vol.141 , pp. 529-535
    • Naess, I.A.1    Chritiansen, S.C.2    Romundstad, P.R.3    Cannegieter, S.C.4    Blom, H.J.5    Rosendaal, F.R.6    Hammerstrom, J.7
  • 6
    • 0942290719 scopus 로고    scopus 로고
    • New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy?
    • Johnson WG, Stenroos ES, Spychala JR, Chatkupt S, Ming SX, Buyske S (2004) New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy? Am J Med Genet 124A:339-345
    • (2004) Am J Med Genet , vol.124 A , pp. 339-345
    • Johnson, W.G.1    Stenroos, E.S.2    Spychala, J.R.3    Chatkupt, S.4    Ming, S.X.5    Buyske, S.6
  • 7
    • 33845531853 scopus 로고    scopus 로고
    • Molecular genetic analysis of the human dihydrofolate reductase gene: Relation with plasma total homocysteine, serum and red blood cell folate levels
    • Gellekink H, Blom HJ, van der Linden IJM, den Heijer M (2007) Molecular genetic analysis of the human dihydrofolate reductase gene: Relation with plasma total homocysteine, serum and red blood cell folate levels. Eur J Hum Genet 15:103-109
    • (2007) Eur J Hum Genet , vol.15 , pp. 103-109
    • Gellekink, H.1    Blom, H.J.2    van der Linden, I.J.M.3    den Heijer, M.4
  • 8
    • 15744388471 scopus 로고    scopus 로고
    • Common dihydrofolate reductase 19-base pair deletion allele: A novel risk factor for preterm delivery
    • Johnson WG, Scholl TO, Spychala JR, Buyske S, Stenroos ES, Chen X (2005) Common dihydrofolate reductase 19-base pair deletion allele: A novel risk factor for preterm delivery. Am J Clin Nutr 81:664-668
    • (2005) Am J Clin Nutr , vol.81 , pp. 664-668
    • Johnson, W.G.1    Scholl, T.O.2    Spychala, J.R.3    Buyske, S.4    Stenroos, E.S.5    Chen, X.6
  • 11
    • 33846989362 scopus 로고    scopus 로고
    • Prevalence of factor V 1691G-A (Leiden) and prothrombin G20210A polymorphisms and the risk of venous thrombosis among cancer patients
    • Eroglu A, Ulu A, Cam R, Kurtman C, Akar N (2007) Prevalence of factor V 1691G-A (Leiden) and prothrombin G20210A polymorphisms and the risk of venous thrombosis among cancer patients. J Thromb Thrombolysis 23:31-34
    • (2007) J Thromb Thrombolysis , vol.23 , pp. 31-34
    • Eroglu, A.1    Ulu, A.2    Cam, R.3    Kurtman, C.4    Akar, N.5
  • 13
    • 0037096971 scopus 로고    scopus 로고
    • Impact of thrombophilic gene mutations on thrombosis risk in patients with gastrointestinal carcinoma
    • Pihusch R, Danzl G, Scholz M, Harich D, Pihusch M, Lohse P (2002) Impact of thrombophilic gene mutations on thrombosis risk in patients with gastrointestinal carcinoma. Cancer 94:3120-3126
    • (2002) Cancer , vol.94 , pp. 3120-3126
    • Pihusch, R.1    Danzl, G.2    Scholz, M.3    Harich, D.4    Pihusch, M.5    Lohse, P.6
  • 14
    • 0037499810 scopus 로고    scopus 로고
    • Prvalence of factor V Leiden, FII G20210A, FXIII Val34Leu and MTHFR C677T polymorphisms in cancer patients with and without venous thrombosis
    • Ramacciotti E, Wolosker N, Peuch-Leao P, Zeratti EA, Gusson PR, del Giglio A, Franco RF (2003) Prvalence of factor V Leiden, FII G20210A, FXIII Val34Leu and MTHFR C677T polymorphisms in cancer patients with and without venous thrombosis. Thromb Res 109:171-174
    • (2003) Thromb Res , vol.109 , pp. 171-174
    • Ramacciotti, E.1    Wolosker, N.2    Peuch-Leao, P.3    Zeratti, E.A.4    Gusson, P.R.5    del Giglio, A.6    Franco, R.F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.