Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults

Journal of Nutrition

Volumn 142, Issue 8, 2012, Pages 1554-1560

  Moorthy, Denish ^a   Peter, Inga ^c   Scott, Tammy M ^a,d   Parnell, Laurence D ^a   Lai, Chao Qiang ^a   Crott, Jimmy W ^a   Ordovás, José M ^a   Selhub, Jacob ^a   Griffith, John ^d   Rosenberg, Irwin H ^a   Tucker, Katherine L ^b   Troen, Aron M ^a,e  

^a TUFTS UNIVERSITY   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d TUFTS MEDICAL CENTER   (United States)

^e HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; PANTOTHENIC ACID;

ADULT; AFRICAN AMERICAN; AGED; ANTHROPOMETRIC PARAMETERS; ARTICLE; ATTENTION; CAUCASIAN; CENTER FOR EPIDEMIOLOGICAL STUDIES DEPRESSION SCALE; COGNITION; COGNITIVE DEFECT; DEPRESSION; ETHNICITY; EXECUTIVE FUNCTION; FEMALE; GENETIC ASSOCIATION; GENOTYPE; GROUPS BY AGE; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MEMORY; MINI MENTAL STATE EXAMINATION; NEUROPSYCHOLOGICAL TEST; OUTCOME ASSESSMENT; PREVALENCE; QUESTIONNAIRE; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; VITAMIN BLOOD LEVEL;

ADULT; AGED; COGNITION DISORDERS; COHORT STUDIES; CROSS-SECTIONAL STUDIES; DEPRESSION; FEMALE; FOLIC ACID; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HOMOCYSTEINE; HUMANS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; POLYMORPHISM, GENETIC; VITAMIN B 12; VITAMIN B 6;

EID: 84866276547     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.112.161828     Document Type: Article

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