-
1
-
-
0021319887
-
The functional human dihydrofolate reductase gene
-
Chen, M. J., Shimada, T., Moulton, A. D., Cline, A., Humphries, R. K., Maizel, J. and Nienhuis, A. W.: The functional human dihydrofolate reductase gene. J. Biol. Chem., 259: 3933-3943 (1984).
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 3933-3943
-
-
Chen, M.J.1
Shimada, T.2
Moulton, A.D.3
Cline, A.4
Humphries, R.K.5
Maizel, J.6
Nienhuis, A.W.7
-
2
-
-
0025361947
-
Dihydrofolate reductase as a therapeutic target
-
Schweitzer, B. I., Dicker, A. P. and Bertino, J. R.: Dihydrofolate reductase as a therapeutic target. FASEB. J., 4: 2441-2452 (1990).
-
(1990)
FASEB. J.
, vol.4
, pp. 2441-2452
-
-
Schweitzer, B.I.1
Dicker, A.P.2
Bertino, J.R.3
-
3
-
-
0037134042
-
Divergent regulation of dihydrofolate reductase between malaria parasite and human host
-
Zhang, K. and Rathod, P. K.: Divergent regulation of dihydrofolate reductase between malaria parasite and human host. Science., 296: 545-547 (2002).
-
(2002)
Science.
, vol.296
, pp. 545-547
-
-
Zhang, K.1
Rathod, P.K.2
-
4
-
-
65549139809
-
Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis
-
Hayashi, H., Fujimaki, C., Daimon, T., Tsuboi, S., Matsuyama, T. and Itoh, K.: Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis. J. Clin. Pharm. Ther., 34: 355-361 (2009).
-
(2009)
J. Clin. Pharm. Ther.
, vol.34
, pp. 355-361
-
-
Hayashi, H.1
Fujimaki, C.2
Daimon, T.3
Tsuboi, S.4
Matsuyama, T.5
Itoh, K.6
-
5
-
-
34147122766
-
Genetic polymorphism of C452T (T127I) in human gammaglutamyl hydrolase in a Japanese population
-
Hayashi, H., Fujimaki, C., Inoue, K., Suzuki, T. and Itoh, K.: Genetic polymorphism of C452T (T127I) in human gammaglutamyl hydrolase in a Japanese population. Biol. Pharm. Bull., 30: 839-841 (2007).
-
(2007)
Biol. Pharm. Bull.
, vol.30
, pp. 839-841
-
-
Hayashi, H.1
Fujimaki, C.2
Inoue, K.3
Suzuki, T.4
Itoh, K.5
-
6
-
-
0024808080
-
Folylpolyglutamate synthesis and role in the regulation of one-carbon metabolism
-
Shane, B.: Folylpolyglutamate synthesis and role in the regulation of one-carbon metabolism. Vitam. Horm., 45: 263-335 (1989).
-
(1989)
Vitam. Horm.
, vol.45
, pp. 263-335
-
-
Shane, B.1
-
7
-
-
0344393780
-
Resistance to antifolates
-
Zhao, R. and Goldman, I. D.: Resistance to antifolates. Oncogene., 22: 7431-7457 (2003).
-
(2003)
Oncogene.
, vol.22
, pp. 7431-7457
-
-
Zhao, R.1
Goldman, I.D.2
-
8
-
-
0141532208
-
An intron is required for dihydrofolate reductase protein stability
-
Noe, V., MacKenzie, S. and Ciudad, C. J.: An intron is required for dihydrofolate reductase protein stability. J. Biol. Chem., 278: 38292-38300 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38292-38300
-
-
Noe, V.1
Mackenzie, S.2
Ciudad, C.J.3
-
9
-
-
0942290719
-
New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy
-
Johnson, W. G., Stenroos, E. S., Spychala, J. R., Chatkupt, S., Ming, S. X. and Buyske, S.: New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy? Am. J. Med. Genet. A., 124A: 339-345 (2004).
-
(2004)
Am. J. Med. Genet. A.
, vol.124 A
, pp. 339-345
-
-
Johnson, W.G.1
Stenroos, E.S.2
Spychala, J.R.3
Chatkupt, S.4
Ming, S.X.5
Buyske, S.6
-
10
-
-
15744388471
-
Common dihydrofolate reductase 19- base pair deletion allele: A novel risk factor for preterm delivery
-
Johnson, W. G., Scholl, T. O., Spychala, J. R., Buyske, S., Stenroos, E. S. and Chen, X.: Common dihydrofolate reductase 19- base pair deletion allele: a novel risk factor for preterm delivery. Am. J. Clin. Nutr., 81: 664-668 (2005).
-
(2005)
Am. J. Clin. Nutr.
, vol.81
, pp. 664-668
-
-
Johnson, W.G.1
Scholl, T.O.2
Spychala, J.R.3
Buyske, S.4
Stenroos, E.S.5
Chen, X.6
-
11
-
-
34447643277
-
Preliminary evidence for involvement of the folate gene polymorphism 19 bp deletion-DHFR in occurrence of autism
-
Adams, M., Lucock, M., Stuart, J., Fardell, S., Baker, K. and Ng, X.: Preliminary evidence for involvement of the folate gene polymorphism 19 bp deletion-DHFR in occurrence of autism. Neurosci. Lett., 422: 24-29 (2007).
-
(2007)
Neurosci. Lett.
, vol.422
, pp. 24-29
-
-
Adams, M.1
Lucock, M.2
Stuart, J.3
Fardell, S.4
Baker, K.5
Ng, X.6
-
12
-
-
67749114009
-
Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: Effects on methotrexate-related toxicity and survival
-
Ongaro, A., De Mattei, M., Della Porta, M. G., Rigolin, G., Ambrosio, C., Di Raimondo, F., Pellati, A., Masieri, F. F., Caruso, A., Catozzi, L. and Gemmati, D.: Gene polymorphisms in folate metabolizing enzymes in adult acute lymphoblastic leukemia: effects on methotrexate-related toxicity and survival. Haematologica, 94: 1391-1398 (2009).
-
(2009)
Haematologica.
, vol.94
, pp. 1391-1398
-
-
Ongaro, A.1
de Mattei, M.2
della Porta, M.G.3
Rigolin, G.4
Ambrosio, C.5
Di Raimondo, F.6
Pellati, A.7
Masieri, F.F.8
Caruso, A.9
Catozzi, L.10
Gemmati, D.11
-
13
-
-
33845531853
-
Molecular genetic analysis of the human dihydrofolate reductase gene: Relation with plasma total homocysteine, serum and red blood cell folate levels
-
Gellekink, H., Blom, H. J., van der Linden, I. J. and den Heijer, M.: Molecular genetic analysis of the human dihydrofolate reductase gene: relation with plasma total homocysteine, serum and red blood cell folate levels. Eur. J. Hum. Genet., 15: 103-109 (2007).
-
(2007)
Eur. J. Hum. Genet.
, vol.15
, pp. 103-109
-
-
Gellekink, H.1
Blom, H.J.2
van der Linden, I.J.3
den Heijer, M.4
-
14
-
-
34249903333
-
The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population
-
Parle-McDermott, A., Pangilinan, F., Mills, J. L., Kirke, P. N., Gibney, E.R., Troendle, J., O'Leary, V. B., Molloy, A. M., Conley, M., Scott, J. M. and Brody, L. C.: The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population. Am. J. Med. Genet. A., 143A: 1174-1180 (2007).
-
(2007)
Am. J. Med. Genet. A.
, vol.143 A
, pp. 1174-1180
-
-
Parle-McDermott, A.1
Pangilinan, F.2
Mills, J.L.3
Kirke, P.N.4
Gibney, E.R.5
Troendle, J.6
O'Leary, V.B.7
Molloy, A.M.8
Conley, M.9
Scott, J.M.10
Brody, L.C.11
-
15
-
-
67749111879
-
DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukaemia: Is the risk reduction due to intracellular folate unbalancing
-
Gemmati, D., De Mattei, M., Catozzi, L., Della Porta, M., Serino, M. L., Ambrosio, C., Cuneo, A., Friso, S., Krampera, M., Orioli, E., Zeri, G. and Ongaro, A.: DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukaemia: is the risk reduction due to intracellular folate unbalancing? Am. J. Hematol., 84: 526-529 (2009).
-
(2009)
Am. J. Hematol.
, vol.84
, pp. 526-529
-
-
Gemmati, D.1
de Mattei, M.2
Catozzi, L.3
della Porta, M.4
Serino, M.L.5
Ambrosio, C.6
Cuneo, A.7
Friso, S.8
Krampera, M.9
Orioli, E.10
Zeri, G.11
Ongaro, A.12
-
16
-
-
67349108801
-
Dihydrofolate reductase (DHRF) 19-bp intron-1 deletion and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms in breast cancer
-
Cam, R., Eroglu, A., Egin, Y. and Akar, N.: Dihydrofolate reductase (DHRF) 19-bp intron-1 deletion and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms in breast cancer. Breast. Cancer. Res. Treat., 115: 431-432 (2009).
-
(2009)
Breast. Cancer. Res. Treat.
, vol.115
, pp. 431-432
-
-
Cam, R.1
Eroglu, A.2
Egin, Y.3
Akar, N.4
-
17
-
-
0022137053
-
Weekly pulse methotrexate in rheumatoid arthritis. Clinical and immunologic effects in a randomized, double-blind study
-
Andersen, P. A., West, S. G., O'Dell, J. R., Via, C. S., Claypool, R. G. and Kotzin B. L.: Weekly pulse methotrexate in rheumatoid arthritis. Clinical and immunologic effects in a randomized, double-blind study. Ann. Intern. Med., 103: 489-496 (1985).
-
(1985)
Ann. Intern. Med.
, vol.103
, pp. 489-496
-
-
Andersen, P.A.1
West, S.G.2
O'Dell, J.R.3
Via, C.S.4
Claypool, R.G.5
Kotzin, B.L.6
-
18
-
-
0021923633
-
Efficacy of low-dose methotrexate in rheumatoid arthritis
-
Weinblatt, M. E., Coblyn, J. S., Fox, D. A., Fraser, P. A., Holdsworth, D. E., Glass, D. N. and Trentham, D. E.: Efficacy of low-dose methotrexate in rheumatoid arthritis. N. Engl. J. Med., 312, 818-822 (1985).
-
(1985)
N. Engl. J. Med.
, vol.312
, pp. 818-822
-
-
Weinblatt, M.E.1
Coblyn, J.S.2
Fox, D.A.3
Fraser, P.A.4
Holdsworth, D.E.5
Glass, D.N.6
Trentham, D.E.7
-
19
-
-
14544292345
-
Determination of the clinical optimal dose of L-377 (methotrexate capsule) for the treatment of rheumatoid arthritis
-
Kashiwazaki, A., Ichikawa, Y., Sugawara, S., Nagaya, I., Kawai, S., Hakota, M., Nakashima, M. and Mizushima, Y.: Determination of the clinical optimal dose of L-377 (methotrexate capsule) for the treatment of rheumatoid arthritis. Jpn. J. Inflamm., 16: 437-458 (1996).
-
(1996)
Jpn. J. Inflamm.
, vol.16
, pp. 437-458
-
-
Kashiwazaki, A.1
Ichikawa, Y.2
Sugawara, S.3
Nagaya, I.4
Kawai, S.5
Hakota, M.6
Nakashima, M.7
Mizushima, Y.8
-
20
-
-
0036169930
-
Guidelines for the management of rheumatoid arthritis: 2002 Update
-
American College of Rheumatology Subcommittee on Rheumatoid Arthritis Guidelines
-
American College of Rheumatology Subcommittee on Rheumatoid Arthritis Guidelines, Guidelines for the management of rheumatoid arthritis: 2002 Update. Arthritis Rheum., 46: 328-346 (2002)
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 328-346
-
-
|