Non-thermal plasma induces AKT degradation through turn-on the MUL1 E3 ligase in head and neck cancer

Oncotarget

Volumn 6, Issue 32, 2015, Pages 33382-33396

  Kim, Sun Yong ^a   Kim, Haeng Jun ^a,b   Kang, Sung Un ^a   Kim, Yang Eun ^a,b   Park, Ju Kyeong ^a,b   Shin, Yoo Seob ^a   Kim, Yeon Soo ^a   Lee, Keunho ^c   Kim, Chul Ho ^a,b  

^a Ajou University School of Medicine   (South Korea)

^b Ajou University   (South Korea)

^c PSM America Inc   (United States)

Author keywords

AKT ubiquitination; Head and neck cancer (HNC); Liquid type plasma (LTP); Mitochondrial E3 ubiquitin protein ligase 1 (MUL1); Non thermal plasma (NTP)

Indexed keywords

MITOCHONDRIAL E3 UBIQUITIN PROTEIN LIGASE 1; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; MITOCHONDRIAL PROTEIN; MUL1 PROTEIN, MOUSE; ONCOPROTEIN; PLASMA GAS; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL DEATH; CELL MEDIATED CYTOTOXICITY; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PLASMA GAS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UBIQUITINATION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; DRUG EFFECTS; DRUG SCREENING; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; HEAD AND NECK TUMOR; METABOLISM; NUDE MOUSE; PATHOLOGY; PHARMACOLOGY; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOCHONDRIAL PROTEINS; ONCOGENE PROTEIN V-AKT; PLASMA GASES; PROTEOLYSIS; RNA, SMALL INTERFERING; UBIQUITIN-PROTEIN LIGASES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84946059793     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5407     Document Type: Article

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