Nonthermal plasma induces head and neck cancer cell death: The potential involvement of mitogen-activated protein kinase-dependent mitochondrial reactive oxygen species

Cell Death and Disease

Volumn 5, Issue 2, 2014, Pages

  Kang, S U ^a   Cho, J H ^b   Chang, J W ^a   Shin, Y S ^a   Kim, K I ^c   Park, J K ^a   Yang, S S ^c   Lee, J S ^c   Moon, E ^c   Lee, K ^d   Kim, C H ^a  

^a Ajou University School of Medicine   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c Ajou University   (South Korea)

^d PSM America Inc   (United States)

Author keywords

apoptosis; head and neck cancer; MAPK; nonthermal plasma; ROS

Indexed keywords

ACETYLCYSTEINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER THERAPY; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NICK END LABELING; NONHUMAN; NONTHERMAL PLASMA; PRIORITY JOURNAL; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PHOSPHORYLATION; PLASMA GASES; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; TIME FACTORS; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84896764186     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.33     Document Type: Article

References (20)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. Cancer J Clin 2009; 59: 225-249.
2. Argiris A, Karamouzis MV, Raben D, Ferris RL. Head and neck cancer. Lancet 2008; 371 1709.
3. Kim CH, Kwon S, Bahn JH, Lee K, Jun SI, Rack PD et al. Effects of atmospheric nonthermal plasma on invasion of colorectal cancer cells. Appl Phys Lett 2010 243701.
4. Sensenig R, Kalghatgi S, Cerchar E, Fridman G, Shereshevsky A, Torabi B et al. Non-Thermal plasma induces apoptosis in melanoma cells via production of intracellular reactive oxygen species. Ann Biomed Eng 2011; 39: 674-687.
5. Kim CH, Bahn JH, Lee SH, Kim GY, Jun SI, Lee K et al. Induction of cell growth arrest by atmospheric non-Thermal plasma in colorectal cancer cells. J Biotechnol 2010; 150 538.
6. Chen N, Garner AL, Chen G, Jing Y, Deng Y, Swanson RJ et al. Nanosecond electric pulses penetrate the nucleus and enhance speckle formation. Biochem Biophys Res Commun 2007; 364: 220-225.
7. Fridman A. Plasma Biology and Plasma Medicine Plasma Chemistry. Cambridge University Press: Cambridge, MA, USA, 2008. pp 10.
8. Jacotot E, Ferri KF, El Hamel C, Brenner C, Druillennec S, Hoebeke J et al. Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2. J Exp Med 2001; 193 519.
9. Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002; 82 95.
10. Kim K, Choi JD, Hong YC, Kim G, Noh EJ, Lee J-S et al. Atmospheric-pressure plasma-jet from micronozzle array and its biological effects on living cells for cancer therapy. Appl Phys Lett 2011; 98: 073701.
11. Kalghatgi S, Kelly CM, Cerchar E, Torabi B, Alekseev O, Fridman A et al. Effects of non-Thermal plasma on mammalian cells. PLoS One 2011; 6: E16270.
12. Vandamme M, Robert E, Lerondel S, Sarron V, Ries D, Dozias S et al. ROS implication in a new antitumor strategy based on non-Thermal plasma. Int J Cancer 2012; 130 2194.
13. Vaux DL, Korsmeyer SJ. Cell death in development. Cell 1999; 96: 245-254.
14. van Loo G, Saelens X, van Gurp M, MacFarlane M, Martin SJ, Vandenabeele P. The role of mitochondrial factors in apoptosis: A Russian roulette with more than one bullet. Cell Death Differen 2002; 9: 1031-1042.
15. Green DR. Apoptotic pathways: Ten minutes to dead. Cell 2005; 121: 671-674.
16. Junttila MR, Li SP, Westermarck J. Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 2008; 22: 954-965.
17. Kim SY, Chu KC, Lee HR, Lee KS, Carey TE. Establishment and characterization of nine new head and neck cancer cell lines. Acta Oto-laryngol 1997; 117: 775-784.
18. Lee BS, Kang SU, Hwang HS, Kim YS, Sung ES, Shin YS et al. An agonistic antibody to human death receptor 4 induces apoptotic cell death in head and neck cancer cells through mitochondrial ROS generation. Cancer Lett 2012; 322: 45-57.
19. Pyun JH, Kang SU, Hwang HS, Oh YT, Kang SH, Lim YA et al. Epicatechin inhibits radiation-induced auditory cell death by suppression of reactive oxygen species generation. Neuroscience 2011; 199: 410-420.
20. Lim YC, Park HY, Hwang HS, Kang SU, Pyun JH, Lee MH et al. (-)-Epigallocatechin-3-gallate (EGCG) inhibits HGF-induced invasion and metastasis in hypopharyngeal carcinoma cells. Cancer Lett 2008; 271: 140-152.