Sensorimotor Cortex Injection of Adeno-Associated Viral Vector Mediates Knockout of PTEN in Neurons of the Brain and Spinal Cord of Mice

Journal of Molecular Neuroscience

Volumn 57, Issue 4, 2015, Pages 470-476

  Yang, Ping ^a   Qin, Yu ^a   Zhang, Wen ^a   Bian, Zhiqun ^a   Wang, Ruiqi ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Adeno associated virus (AAV); Axonal transport; Gene therapy; Hippocampus; Sensorimotor cortex; Spinal cord

Indexed keywords

CRE RECOMBINASE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; S6 KINASE; VIRUS VECTOR; PTEN PROTEIN, MOUSE;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE INACTIVATION; GENE THERAPY; HIPPOCAMPUS; IMMUNOHISTOLOGY; LOXP SITE; MOUSE; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; QUANTITATIVE ANALYSIS; SENSORIMOTOR CORTEX; SIGNAL TRANSDUCTION; SPINAL CORD; VIRAL GENE DELIVERY SYSTEM; ADMINISTRATION AND DOSAGE; ANIMAL; CYTOLOGY; DEPENDOPARVOVIRUS; GENE VECTOR; GENETICS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; PROCEDURES;

ANIMALS; DEPENDOVIRUS; GENE KNOCKOUT TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; MICE; NEURONS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SENSORIMOTOR CORTEX; SPINAL CORD;

EID: 84945941485     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-015-0610-x     Document Type: Article

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