Proteasomal degradation of preemptive quality control (pQC) substrates is mediated by an AIRAPL-p97 complex

Molecular Biology of the Cell

Volumn 26, Issue 21, 2015, Pages 3719-3727

  Braunstein, Ilana ^a   Zach, Lolita ^a   Allan, Susanne ^b   Kalies, Kai Uwe ^b   Stanhill, Ariel ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b UNIVERSITY OF LÜBECK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; CHAPERONE; GLYCOSYLATED PROTEIN; INSULIN; POLYPEPTIDE; PREPROINSULIN; PROTEIN P97; SIGNAL PEPTIDE; TRANSLOCON; VASCULAR CELL ADHESION MOLECULE 1; CARRIER PROTEIN; CELL CYCLE PROTEIN; KARYOPHERIN BETA; KPNB1 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEASOME; UBIQUITIN; ZFAND2B PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CONTROLLED STUDY; DOG; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENDOPLASMIC RETICULUM MEMBRANE; ENZYME DEGRADATION; ENZYME SUBSTRATE; GLYCOSYLATION; HUMAN; HUMAN CELL; NONHUMAN; PREEMPTIVE QUALITY CONTROL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN PROCESSING; QUALITY CONTROL; CELL CULTURE; ENDOPLASMIC RETICULUM; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; UBIQUITINATION;

BETA KARYOPHERINS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELLS, CULTURED; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; HEK293 CELLS; HUMANS; MOLECULAR CHAPERONES; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SORTING SIGNALS; UBIQUITIN; UBIQUITINATION;

EID: 84945916821     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E15-02-0085     Document Type: Article

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