Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1

Nature

Volumn 436, Issue 7048, 2005, Pages 290-293

  Besemer, Jürgen ^a,c   Harant, Hanna ^a   Wang, Shirley ^a   Oberhauser, Berndt ^a   Marquardt, Katharina ^a,c   Foster, Carolyn A ^a   Schreiner, Erwin P ^a   De Vries, Jan E ^a   Dascher Nadel, Christiane ^a,b   Lindley, Ivan J D ^a  

^a Novartis Institutes for BioMedical Research Vienna   (Austria)

^b INSERM   (France)

^c NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; BIOSYNTHESIS; DISEASES; DRUG PRODUCTS; FUNGI; MOLECULES; PROTEINS;

ADHESION MOLECULES; FUNGUS-DERIVED CYCLOPEPTOLIDE; THERAPEUTIC INTERVENTION; VASCULAR CELLS;

CELLS;

BETA ACTIN; CAM 741; CYCLOPEPTIDE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ESTER DERIVATIVE; HUN 7293; MEMBRANE PROTEIN; PROTEIN INHIBITOR; TRANSLOCON; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; CAM741; PEPTIDE HYDROLASE; SEC61 PROTEIN; SIGNAL PEPTIDE;

BIOLOGY;

ARTICLE; CONTROLLED STUDY; CYTOSOL; DRUG EFFECT; DRUG INHIBITION; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; ENZYME SPECIFICITY; GENE DELETION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CELL LINE; CHEMISTRY; DOSE RESPONSE; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; SECRETION; SENSITIVITY AND SPECIFICITY;

FUNGI;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PEPTIDES, CYCLIC; PROTEIN BIOSYNTHESIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; SENSITIVITY AND SPECIFICITY; SEQUENCE DELETION; SUBSTRATE SPECIFICITY; TRANSFECTION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 22444433005     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03670     Document Type: Article

References (15)

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