Reduced Translocation of Nascent Prion Protein During ER Stress Contributes to Neurodegeneration

Developmental Cell

Volumn 15, Issue 3, 2008, Pages 359-370

  Rane, Neena S ^a   Kang, Sang Wook ^a   Chakrabarti, Oishee ^a   Feigenbaum, Lionel ^b   Hegde, Ramanujan S ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

CELLBIO; HUMDISEASE; PROTEINS

Indexed keywords

PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HISTOPATHOLOGY; MAMMAL; MOUSE; NERVE DEGENERATION; NONHUMAN; PATHOGENESIS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; PROTEIN VARIANT; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; BRAIN; CRICETINAE; CRICETULUS; ENDOPLASMIC RETICULUM; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NERVE DEGENERATION; OXIDATIVE STRESS; PRIONS; PROTEIN SORTING SIGNALS; PRPSC PROTEINS; RECOMBINANT FUSION PROTEINS; SCRAPIE;

MAMMALIAN PRION; MUS MUSCULUS;

EID: 51449098355     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2008.06.015     Document Type: Article

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