메뉴 건너뛰기




Volumn 299, Issue , 2016, Pages 23-29

Tolerance and immune suppression in the tumor microenvironment

Author keywords

Immune suppression; MDSC; Myeloid derived suppressor cells; Tolerance; Tumor immunology

Indexed keywords

CELL MARKER; IMMUNOMODULATING AGENT;

EID: 84945908483     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2015.09.011     Document Type: Article
Times cited : (42)

References (113)
  • 1
    • 0000658958 scopus 로고
    • Immunogenetic consequences of vascular anastomoses between bovine twins
    • [1] Owen, R.D., Immunogenetic consequences of vascular anastomoses between bovine twins. Science 102 (1945), 400–401.
    • (1945) Science , vol.102 , pp. 400-401
    • Owen, R.D.1
  • 2
    • 0001415346 scopus 로고
    • Über den jetzigen stand der karzinomforschung
    • [2] Ehrlich, P., Über den jetzigen stand der karzinomforschung. Ned. Tijdschr. Geneeskd. 5 (1909), 273–290.
    • (1909) Ned. Tijdschr. Geneeskd. , vol.5 , pp. 273-290
    • Ehrlich, P.1
  • 3
    • 0000161413 scopus 로고
    • The treatment of malignant tumors by repeated inoculations of erysipelas: with a report of ten original cases
    • [3] Coley, W., The treatment of malignant tumors by repeated inoculations of erysipelas: with a report of ten original cases. Am. J. Med. Sci. 105 (1893), 487–511.
    • (1893) Am. J. Med. Sci. , vol.105 , pp. 487-511
    • Coley, W.1
  • 4
    • 0002314163 scopus 로고
    • Discussion of cellular and humoral aspects of the hypersensitivity states
    • H. Lawrence Hoeber-Harper New York
    • [4] Thomas, L., Discussion of cellular and humoral aspects of the hypersensitivity states. Lawrence, H., (eds.) Cellular and Humoral Aspects of Hypersensitivity, 1959, Hoeber-Harper, New York, 529–532.
    • (1959) Cellular and Humoral Aspects of Hypersensitivity , pp. 529-532
    • Thomas, L.1
  • 5
    • 0011542558 scopus 로고
    • Immunological factors in the process of carcinogenesis
    • [5] Burnet, M., Immunological factors in the process of carcinogenesis. Br. Med. Bull. 20 (1964), 154–158.
    • (1964) Br. Med. Bull. , vol.20 , pp. 154-158
    • Burnet, M.1
  • 6
    • 0014191608 scopus 로고
    • Immunological aspects of malignant disease
    • [6] Burnet, F.M., Immunological aspects of malignant disease. Lancet 1 (1967), 1171–1174.
    • (1967) Lancet , vol.1 , pp. 1171-1174
    • Burnet, F.M.1
  • 7
    • 0016649531 scopus 로고
    • Immunodepression and malignancy
    • [7] Stutman, O., Immunodepression and malignancy. Adv. Cancer Res. 22 (1975), 261–422.
    • (1975) Adv. Cancer Res. , vol.22 , pp. 261-422
    • Stutman, O.1
  • 8
    • 0018742391 scopus 로고
    • Chemical carcinogenesis in nude mice: comparison between nude mice from homozygous matings and heterozygous matings and effect of age and carcinogen dose
    • [8] Stutman, O., Chemical carcinogenesis in nude mice: comparison between nude mice from homozygous matings and heterozygous matings and effect of age and carcinogen dose. J. Natl Cancer Inst. 62 (1979), 353–358.
    • (1979) J. Natl Cancer Inst. , vol.62 , pp. 353-358
    • Stutman, O.1
  • 9
    • 0023275032 scopus 로고
    • The composition of the T cell receptor repertoire in nude mice
    • [9] Maleckar, J.R., Sherman, L.A., The composition of the T cell receptor repertoire in nude mice. J. Immunol. 138 (1987), 3873–3876.
    • (1987) J. Immunol. , vol.138 , pp. 3873-3876
    • Maleckar, J.R.1    Sherman, L.A.2
  • 10
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • [10] Shankaran, V., Ikeda, H., Bruce, A.T., White, J.M., Swanson, P.E., Old, L.J., Schreiber, R.D., IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410 (2001), 1107–1111.
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6    Schreiber, R.D.7
  • 11
    • 0004229008 scopus 로고
    • The Production of Antibodies
    • McMillan London
    • [11] Burnet, F.M., Fenner, F., The Production of Antibodies. 1949, McMillan, London.
    • (1949)
    • Burnet, F.M.1    Fenner, F.2
  • 12
    • 0005984244 scopus 로고
    • Actively acquired tolerance of foreign cells
    • [12] Billingham, R.E., Brent, L., Medawar, P.B., Actively acquired tolerance of foreign cells. Nature 172 (1953), 603–606.
    • (1953) Nature , vol.172 , pp. 603-606
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 13
    • 0029643982 scopus 로고
    • Genetic instability and tumor cell variation: implications for immunotherapy
    • [13] Fenton, R.G., Longo, D.L., Genetic instability and tumor cell variation: implications for immunotherapy. J. Natl Cancer Inst. 87 (1995), 241–243.
    • (1995) J. Natl Cancer Inst. , vol.87 , pp. 241-243
    • Fenton, R.G.1    Longo, D.L.2
  • 14
    • 0021558066 scopus 로고
    • Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships
    • [14] Strober, S., Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships. Annu. Rev. Immunol. 2 (1984), 219–237.
    • (1984) Annu. Rev. Immunol. , vol.2 , pp. 219-237
    • Strober, S.1
  • 15
    • 0025181322 scopus 로고
    • Myelopoiesis-associated suppressor-cell activity in mice with Lewis lung carcinoma tumors: interferon-gamma plus tumor necrosis factor-alpha synergistically reduce suppressor cell activity
    • [15] Young, M.R., Young, M.E., Wright, M.A., Myelopoiesis-associated suppressor-cell activity in mice with Lewis lung carcinoma tumors: interferon-gamma plus tumor necrosis factor-alpha synergistically reduce suppressor cell activity. Int. J. Cancer 46 (1990), 245–250.
    • (1990) Int. J. Cancer , vol.46 , pp. 245-250
    • Young, M.R.1    Young, M.E.2    Wright, M.A.3
  • 16
    • 0031588347 scopus 로고    scopus 로고
    • Increased presence of CD34+ cells in the peripheral blood of head and neck cancer patients and their differentiation into dendritic cells
    • [16] Garrity, T., Pandit, R., Wright, M.A., Benefield, J., Keni, S., Young, M.R., Increased presence of CD34+ cells in the peripheral blood of head and neck cancer patients and their differentiation into dendritic cells. Int. J. Cancer 73 (1997), 663–669.
    • (1997) Int. J. Cancer , vol.73 , pp. 663-669
    • Garrity, T.1    Pandit, R.2    Wright, M.A.3    Benefield, J.4    Keni, S.5    Young, M.R.6
  • 17
    • 0029833732 scopus 로고    scopus 로고
    • Mechanisms of immune suppression in patients with head and neck cancer: influence on the immune infiltrate of the cancer
    • [17] Young, M.R., Wright, M.A., Lozano, Y., Matthews, J.P., Benefield, J., Prechel, M.M., Mechanisms of immune suppression in patients with head and neck cancer: influence on the immune infiltrate of the cancer. Int. J. Cancer 67 (1996), 333–338.
    • (1996) Int. J. Cancer , vol.67 , pp. 333-338
    • Young, M.R.1    Wright, M.A.2    Lozano, Y.3    Matthews, J.P.4    Benefield, J.5    Prechel, M.M.6
  • 18
    • 0030979282 scopus 로고    scopus 로고
    • Increased recurrence and metastasis in patients whose primary head and neck squamous cell carcinomas secreted granulocyte-macrophage colony-stimulating factor and contained CD34+ natural suppressor cells
    • [18] Young, M.R., Wright, M.A., Lozano, Y., Prechel, M.M., Benefield, J., Leonetti, J.P., Collins, S.L., Petruzzelli, G.J., Increased recurrence and metastasis in patients whose primary head and neck squamous cell carcinomas secreted granulocyte-macrophage colony-stimulating factor and contained CD34+ natural suppressor cells. Int. J. Cancer 74 (1997), 69–74.
    • (1997) Int. J. Cancer , vol.74 , pp. 69-74
    • Young, M.R.1    Wright, M.A.2    Lozano, Y.3    Prechel, M.M.4    Benefield, J.5    Leonetti, J.P.6    Collins, S.L.7    Petruzzelli, G.J.8
  • 20
    • 0032533478 scopus 로고    scopus 로고
    • Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells
    • [20] Bronte, V., Wang, M., Overwijk, W.W., Surman, D.R., Pericle, F., Rosenberg, S.A., Restifo, N.P., Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells. J. Immunol. 161 (1998), 5313–5320.
    • (1998) J. Immunol. , vol.161 , pp. 5313-5320
    • Bronte, V.1    Wang, M.2    Overwijk, W.W.3    Surman, D.R.4    Pericle, F.5    Rosenberg, S.A.6    Restifo, N.P.7
  • 21
    • 0035339932 scopus 로고    scopus 로고
    • Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells
    • [21] Gabrilovich, D.I., Velders, M.P., Sotomayor, E.M., Kast, W.M., Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells. J. Immunol. 166 (2001), 5398–5406.
    • (2001) J. Immunol. , vol.166 , pp. 5398-5406
    • Gabrilovich, D.I.1    Velders, M.P.2    Sotomayor, E.M.3    Kast, W.M.4
  • 22
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients
    • [22] Schmielau, J., Finn, O.J., Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients. Cancer Res. 61 (2001), 4756–4760.
    • (2001) Cancer Res. , vol.61 , pp. 4756-4760
    • Schmielau, J.1    Finn, O.J.2
  • 24
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • [24] Gabrilovich, D.I., Nagaraj, S., Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9 (2009), 162–174.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 25
    • 4544220702 scopus 로고    scopus 로고
    • Both expansion of regulatory GR1+ CD11b+ myeloid cells and anergy of T lymphocytes participate in hyporesponsiveness of the lung-associated immune system during acute toxoplasmosis
    • [25] Voisin, M.B., Buzoni-Gatel, D., Bout, D., Velge-Roussel, F., Both expansion of regulatory GR1+ CD11b+ myeloid cells and anergy of T lymphocytes participate in hyporesponsiveness of the lung-associated immune system during acute toxoplasmosis. Infect. Immun. 72 (2004), 5487–5492.
    • (2004) Infect. Immun. , vol.72 , pp. 5487-5492
    • Voisin, M.B.1    Buzoni-Gatel, D.2    Bout, D.3    Velge-Roussel, F.4
  • 28
    • 84892646386 scopus 로고    scopus 로고
    • HIV type 1 gp120-induced expansion of myeloid derived suppressor cells is dependent on interleukin 6 and suppresses immunity
    • [28] Garg, A., Spector, S.A., HIV type 1 gp120-induced expansion of myeloid derived suppressor cells is dependent on interleukin 6 and suppresses immunity. J. Infect. Dis. 209 (2014), 441–451.
    • (2014) J. Infect. Dis. , vol.209 , pp. 441-451
    • Garg, A.1    Spector, S.A.2
  • 29
    • 84898645210 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection
    • [29] Heim, C.E., Vidlak, D., Scherr, T.D., Kozel, J.A., Holzapfel, M., Muirhead, D.E., Kielian, T., Myeloid-derived suppressor cells contribute to Staphylococcus aureus orthopedic biofilm infection. J. Immunol. 192 (2014), 3778–3792.
    • (2014) J. Immunol. , vol.192 , pp. 3778-3792
    • Heim, C.E.1    Vidlak, D.2    Scherr, T.D.3    Kozel, J.A.4    Holzapfel, M.5    Muirhead, D.E.6    Kielian, T.7
  • 31
    • 77954399377 scopus 로고    scopus 로고
    • Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function
    • [31] Sander, L.E., Sackett, S.D., Dierssen, U., Beraza, N., Linke, R.P., Muller, M., Blander, J.M., Tacke, F., Trautwein, C., Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J. Exp. Med. 207 (2010), 1453–1464.
    • (2010) J. Exp. Med. , vol.207 , pp. 1453-1464
    • Sander, L.E.1    Sackett, S.D.2    Dierssen, U.3    Beraza, N.4    Linke, R.P.5    Muller, M.6    Blander, J.M.7    Tacke, F.8    Trautwein, C.9
  • 32
    • 32044439372 scopus 로고    scopus 로고
    • CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stress
    • [32] Makarenkova, V.P., Bansal, V., Matta, B.M., Perez, L.A., Ochoa, J.B., CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stress. J. Immunol. 176 (2006), 2085–2094.
    • (2006) J. Immunol. , vol.176 , pp. 2085-2094
    • Makarenkova, V.P.1    Bansal, V.2    Matta, B.M.3    Perez, L.A.4    Ochoa, J.B.5
  • 33
    • 79959852117 scopus 로고    scopus 로고
    • Psychological stress is associated with altered levels of myeloid-derived suppressor cells in breast cancer patients
    • [33] Mundy-Bosse, B.L., Thornton, L.M., Yang, H.C., Andersen, B.L., Carson, W.E., Psychological stress is associated with altered levels of myeloid-derived suppressor cells in breast cancer patients. Cell. Immunol. 270 (2011), 80–87.
    • (2011) Cell. Immunol. , vol.270 , pp. 80-87
    • Mundy-Bosse, B.L.1    Thornton, L.M.2    Yang, H.C.3    Andersen, B.L.4    Carson, W.E.5
  • 34
    • 37349003404 scopus 로고    scopus 로고
    • Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice
    • [34] Grizzle, W.E., Xu, X., Zhang, S., Stockard, C.R., Liu, C., Yu, S., Wang, J., Mountz, J.D., Zhang, H.G., Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice. Mech. Ageing Dev. 128 (2007), 672–680.
    • (2007) Mech. Ageing Dev. , vol.128 , pp. 672-680
    • Grizzle, W.E.1    Xu, X.2    Zhang, S.3    Stockard, C.R.4    Liu, C.5    Yu, S.6    Wang, J.7    Mountz, J.D.8    Zhang, H.G.9
  • 37
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • [37] Huang, B., Pan, P.Y., Li, Q., Sato, A.I., Levy, D.E., Bromberg, J., Divino, C.M., Chen, S.H., Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 66 (2006), 1123–1131.
    • (2006) Cancer Res. , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.H.8
  • 39
    • 53349125963 scopus 로고    scopus 로고
    • Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells
    • [39] Sinha, P., Okoro, C., Foell, D., Freeze, H.H., Ostrand-Rosenberg, S., Srikrishna, G., Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells. J. Immunol. 181 (2008), 4666–4675.
    • (2008) J. Immunol. , vol.181 , pp. 4666-4675
    • Sinha, P.1    Okoro, C.2    Foell, D.3    Freeze, H.H.4    Ostrand-Rosenberg, S.5    Srikrishna, G.6
  • 40
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • [40] Youn, J.I., Nagaraj, S., Collazo, M., Gabrilovich, D.I., Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J. Immunol. 181 (2008), 5791–5802.
    • (2008) J. Immunol. , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 42
    • 84908054077 scopus 로고    scopus 로고
    • High mobility group box protein 1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells
    • [42] Parker, K., Sinha, P., Horn, L.A., Clements, V.K., Yang, H.C., Li, J., Tracey, K.J., Ostrand-Rosenberg, S., High mobility group box protein 1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Res., 2014.
    • (2014) Cancer Res.
    • Parker, K.1    Sinha, P.2    Horn, L.A.3    Clements, V.K.4    Yang, H.C.5    Li, J.6    Tracey, K.J.7    Ostrand-Rosenberg, S.8
  • 43
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
    • [43] Sinha, P., Clements, V.K., Bunt, S.K., Albelda, S.M., Ostrand-Rosenberg, S., Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J. Immunol. 179 (2007), 977–983.
    • (2007) J. Immunol. , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rosenberg, S.5
  • 44
    • 84914096079 scopus 로고    scopus 로고
    • Cross-talk among myeloid-derived suppressor cells, macrophages, and tumor cells impacts the inflammatory milieu of solid tumors
    • [44] Beury, D.W., Parker, K.H., Nyandjo, M., Sinha, P., Carter, K.A., Ostrand-Rosenberg, S., Cross-talk among myeloid-derived suppressor cells, macrophages, and tumor cells impacts the inflammatory milieu of solid tumors. J. Leukoc. Biol. 96 (2014), 1109–1118.
    • (2014) J. Leukoc. Biol. , vol.96 , pp. 1109-1118
    • Beury, D.W.1    Parker, K.H.2    Nyandjo, M.3    Sinha, P.4    Carter, K.A.5    Ostrand-Rosenberg, S.6
  • 45
    • 84862127053 scopus 로고    scopus 로고
    • Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression
    • [45] Ostrand-Rosenberg, S., Sinha, P., Beury, D.W., Clements, V.K., Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression. Semin. Cancer Biol., 2012.
    • (2012) Semin. Cancer Biol.
    • Ostrand-Rosenberg, S.1    Sinha, P.2    Beury, D.W.3    Clements, V.K.4
  • 46
    • 59849126377 scopus 로고    scopus 로고
    • Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1
    • [46] Li, H., Han, Y., Guo, Q., Zhang, M., Cao, X., Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J. Immunol. 182 (2009), 240–249.
    • (2009) J. Immunol. , vol.182 , pp. 240-249
    • Li, H.1    Han, Y.2    Guo, Q.3    Zhang, M.4    Cao, X.5
  • 47
    • 34248342290 scopus 로고    scopus 로고
    • Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host
    • [47] Liu, C., Yu, S., Kappes, J., Wang, J., Grizzle, W.E., Zinn, K.R., Zhang, H.G., Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host. Blood 109 (2007), 4336–4342.
    • (2007) Blood , vol.109 , pp. 4336-4342
    • Liu, C.1    Yu, S.2    Kappes, J.3    Wang, J.4    Grizzle, W.E.5    Zinn, K.R.6    Zhang, H.G.7
  • 48
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • [48] Suzuki, E., Kapoor, V., Jassar, A.S., Kaiser, L.R., Albelda, S.M., Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin. Cancer Res. 11 (2005), 6713–6721.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 49
    • 84979691808 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells
    • M. Ratcliffe Elsevier
    • [49] Ostrand-Rosenberg, S., Myeloid-derived suppressor cells. Ratcliffe, M., (eds.) Encyclopedia of Immunobiology, 2016, Elsevier.
    • (2016) Encyclopedia of Immunobiology
    • Ostrand-Rosenberg, S.1
  • 52
  • 53
    • 79954471164 scopus 로고    scopus 로고
    • Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of MCP-1
    • [53] Boelte, K.C., Gordy, L.E., Joyce, S., Thompson, M.A., Yang, L., Lin, P.C., Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of MCP-1. PLoS One, 6, 2011, e18534.
    • (2011) PLoS One , vol.6 , pp. e18534
    • Boelte, K.C.1    Gordy, L.E.2    Joyce, S.3    Thompson, M.A.4    Yang, L.5    Lin, P.C.6
  • 54
    • 80053336355 scopus 로고    scopus 로고
    • Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor
    • [54] Toh, B., Wang, X., Keeble, J., Sim, W.J., Khoo, K., Wong, W.C., Kato, M., Prevost-Blondel, A., Thiery, J.P., Abastado, J.P., Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor. PLoS Biol., 9, 2011, e1001162.
    • (2011) PLoS Biol. , vol.9 , pp. e1001162
    • Toh, B.1    Wang, X.2    Keeble, J.3    Sim, W.J.4    Khoo, K.5    Wong, W.C.6    Kato, M.7    Prevost-Blondel, A.8    Thiery, J.P.9    Abastado, J.P.10
  • 55
    • 33749134855 scopus 로고    scopus 로고
    • TCR zeta down-regulation under chronic inflammation is mediated by myeloid suppressor cells differentially distributed between various lymphatic organs
    • [55] Ezernitchi, A.V., Vaknin, I., Cohen-Daniel, L., Levy, O., Manaster, E., Halabi, A., Pikarsky, E., Shapira, L., Baniyash, M., TCR zeta down-regulation under chronic inflammation is mediated by myeloid suppressor cells differentially distributed between various lymphatic organs. J. Immunol. 177 (2006), 4763–4772.
    • (2006) J. Immunol. , vol.177 , pp. 4763-4772
    • Ezernitchi, A.V.1    Vaknin, I.2    Cohen-Daniel, L.3    Levy, O.4    Manaster, E.5    Halabi, A.6    Pikarsky, E.7    Shapira, L.8    Baniyash, M.9
  • 57
    • 75149123468 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine
    • [57] Srivastava, M.K., Sinha, P., Clements, V.K., Rodriguez, P., Ostrand-Rosenberg, S., Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer Res. 70 (2010), 68–77.
    • (2010) Cancer Res. , vol.70 , pp. 68-77
    • Srivastava, M.K.1    Sinha, P.2    Clements, V.K.3    Rodriguez, P.4    Ostrand-Rosenberg, S.5
  • 58
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by L-arginine metabolism
    • [58] Bronte, V., Zanovello, P., Regulation of immune responses by L-arginine metabolism. Nat. Rev. Immunol. 5 (2005), 641–654.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 64
    • 84915822550 scopus 로고    scopus 로고
    • Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells
    • [64] Burke, M.C., Oei, M.S., Edwards, N.J., Ostrand-Rosenberg, S., Fenselau, C., Ubiquitinated proteins in exosomes secreted by myeloid-derived suppressor cells. J. Proteome Res. 13 (2014), 5965–5972.
    • (2014) J. Proteome Res. , vol.13 , pp. 5965-5972
    • Burke, M.C.1    Oei, M.S.2    Edwards, N.J.3    Ostrand-Rosenberg, S.4    Fenselau, C.5
  • 65
    • 84925611946 scopus 로고    scopus 로고
    • Microenvironmental regulation of therapeutic response in cancer
    • [65] Klemm, F., Joyce, J.A., Microenvironmental regulation of therapeutic response in cancer. Trends Cell Biol. 25 (2015), 198–213.
    • (2015) Trends Cell Biol. , vol.25 , pp. 198-213
    • Klemm, F.1    Joyce, J.A.2
  • 67
    • 67149115417 scopus 로고    scopus 로고
    • Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4
    • [67] Bunt, S.K., Clements, V.K., Hanson, E.M., Sinha, P., Ostrand-Rosenberg, S., Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4. J. Leukoc. Biol. 85 (2009), 996–1004.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 996-1004
    • Bunt, S.K.1    Clements, V.K.2    Hanson, E.M.3    Sinha, P.4    Ostrand-Rosenberg, S.5
  • 68
    • 48549085973 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • [68] Serafini, P., Mgebroff, S., Noonan, K., Borrello, I., Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 68 (2008), 5439–5449.
    • (2008) Cancer Res. , vol.68 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 71
    • 10744220561 scopus 로고    scopus 로고
    • Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence
    • [71] Terabe, M., Matsui, S., Park, J.M., Mamura, M., Noben-Trauth, N., Donaldson, D.D., Chen, W., Wahl, S.M., Ledbetter, S., Pratt, B., Letterio, J.J., Paul, W.E., Berzofsky, J.A., Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence. J. Exp. Med. 198 (2003), 1741–1752.
    • (2003) J. Exp. Med. , vol.198 , pp. 1741-1752
    • Terabe, M.1    Matsui, S.2    Park, J.M.3    Mamura, M.4    Noben-Trauth, N.5    Donaldson, D.D.6    Chen, W.7    Wahl, S.M.8    Ledbetter, S.9    Pratt, B.10    Letterio, J.J.11    Paul, W.E.12    Berzofsky, J.A.13
  • 74
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: linking inflammation and cancer
    • [74] Ostrand-Rosenberg, S., Sinha, P., Myeloid-derived suppressor cells: linking inflammation and cancer. J. Immunol. 182 (2009), 4499–4506.
    • (2009) J. Immunol. , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 75
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • [75] Gabrilovich, D.I., Chen, H.L., Girgis, K.R., Cunningham, H.T., Meny, G.M., Nadaf, S., Kavanaugh, D., Carbone, D.P., Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat. Med. 2 (1996), 1096–1103.
    • (1996) Nat. Med. , vol.2 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3    Cunningham, H.T.4    Meny, G.M.5    Nadaf, S.6    Kavanaugh, D.7    Carbone, D.P.8
  • 76
    • 0033757517 scopus 로고    scopus 로고
    • Chemoattraction of femoral CD34+ progenitor cells by tumor-derived vascular endothelial cell growth factor
    • [76] Young, M.R., Kolesiak, K., Wright, M.A., Gabrilovich, D.I., Chemoattraction of femoral CD34+ progenitor cells by tumor-derived vascular endothelial cell growth factor. Clin. Exp. Metastasis 17 (1999), 881–888.
    • (1999) Clin. Exp. Metastasis , vol.17 , pp. 881-888
    • Young, M.R.1    Kolesiak, K.2    Wright, M.A.3    Gabrilovich, D.I.4
  • 78
    • 77955771348 scopus 로고    scopus 로고
    • GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b−Gr1− bone marrow progenitor cells into myeloid-derived suppressor cells
    • [78] Morales, J.K., Kmieciak, M., Knutson, K.L., Bear, H.D., Manjili, M.H., GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b−Gr1− bone marrow progenitor cells into myeloid-derived suppressor cells. Breast Cancer Res. Treat. 123 (2010), 39–49.
    • (2010) Breast Cancer Res. Treat. , vol.123 , pp. 39-49
    • Morales, J.K.1    Kmieciak, M.2    Knutson, K.L.3    Bear, H.D.4    Manjili, M.H.5
  • 79
    • 4344590947 scopus 로고    scopus 로고
    • High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells
    • [79] Serafini, P., Carbley, R., Noonan, K.A., Tan, G., Bronte, V., Borrello, I., High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells. Cancer Res. 64 (2004), 6337–6343.
    • (2004) Cancer Res. , vol.64 , pp. 6337-6343
    • Serafini, P.1    Carbley, R.2    Noonan, K.A.3    Tan, G.4    Bronte, V.5    Borrello, I.6
  • 80
    • 66149092730 scopus 로고    scopus 로고
    • G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models
    • [80] Shojaei, F., Wu, X., Qu, X., Kowanetz, M., Yu, L., Tan, M., Meng, Y.G., Ferrara, N., G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models. Proc. Natl. Acad. Sci. U.S.A. 106 (2009), 6742–6747.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 6742-6747
    • Shojaei, F.1    Wu, X.2    Qu, X.3    Kowanetz, M.4    Yu, L.5    Tan, M.6    Meng, Y.G.7    Ferrara, N.8
  • 81
    • 29644442445 scopus 로고    scopus 로고
    • Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression
    • [81] Bunt, S.K., Sinha, P., Clements, V.K., Leips, J., Ostrand-Rosenberg, S., Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression. J. Immunol. 176 (2006), 284–290.
    • (2006) J. Immunol. , vol.176 , pp. 284-290
    • Bunt, S.K.1    Sinha, P.2    Clements, V.K.3    Leips, J.4    Ostrand-Rosenberg, S.5
  • 82
    • 35448954376 scopus 로고    scopus 로고
    • Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression
    • [82] Bunt, S.K., Yang, L., Sinha, P., Clements, V.K., Leips, J., Ostrand-Rosenberg, S., Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression. Cancer Res. 67 (2007), 10019–10026.
    • (2007) Cancer Res. , vol.67 , pp. 10019-10026
    • Bunt, S.K.1    Yang, L.2    Sinha, P.3    Clements, V.K.4    Leips, J.5    Ostrand-Rosenberg, S.6
  • 83
    • 34249300128 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
    • [83] Sinha, P., Clements, V.K., Fulton, A.M., Ostrand-Rosenberg, S., Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res. 67 (2007), 4507–4513.
    • (2007) Cancer Res. , vol.67 , pp. 4507-4513
    • Sinha, P.1    Clements, V.K.2    Fulton, A.M.3    Ostrand-Rosenberg, S.4
  • 85
    • 81555228400 scopus 로고    scopus 로고
    • Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells
    • [85] Obermajer, N., Muthuswamy, R., Lesnock, J., Edwards, R.P., Kalinski, P., Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Blood 118 (2011), 5498–5505.
    • (2011) Blood , vol.118 , pp. 5498-5505
    • Obermajer, N.1    Muthuswamy, R.2    Lesnock, J.3    Edwards, R.P.4    Kalinski, P.5
  • 86
    • 84905455438 scopus 로고    scopus 로고
    • Inhibition of tumor-derived prostaglandin-E2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity
    • [86] Mao, Y., Sarhan, D., Steven, A., Seliger, B., Kiessling, R., Lundqvist, A., Inhibition of tumor-derived prostaglandin-E2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity. Clin. Cancer Res. 20 (2014), 4096–4106.
    • (2014) Clin. Cancer Res. , vol.20 , pp. 4096-4106
    • Mao, Y.1    Sarhan, D.2    Steven, A.3    Seliger, B.4    Kiessling, R.5    Lundqvist, A.6
  • 87
    • 33144481709 scopus 로고    scopus 로고
    • Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors
    • [87] Harris, R.E., Beebe-Donk, J., Alshafie, G.A., Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors. BMC Cancer, 6, 2006, 27.
    • (2006) BMC Cancer , vol.6 , pp. 27
    • Harris, R.E.1    Beebe-Donk, J.2    Alshafie, G.A.3
  • 89
    • 33845997430 scopus 로고    scopus 로고
    • Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion
    • [89] Talmadge, J.E., Hood, K.C., Zobel, L.C., Shafer, L.R., Coles, M., Toth, B., Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion. Int. Immunopharmacol. 7 (2007), 140–151.
    • (2007) Int. Immunopharmacol. , vol.7 , pp. 140-151
    • Talmadge, J.E.1    Hood, K.C.2    Zobel, L.C.3    Shafer, L.R.4    Coles, M.5    Toth, B.6
  • 90
    • 77956473075 scopus 로고    scopus 로고
    • COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function
    • [90] Veltman, J.D., Lambers, M.E., van Nimwegen, M., Hendriks, R.W., Hoogsteden, H.C., Aerts, J.G., Hegmans, J.P., COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function. BMC Cancer, 10, 2010, 464.
    • (2010) BMC Cancer , vol.10 , pp. 464
    • Veltman, J.D.1    Lambers, M.E.2    van Nimwegen, M.3    Hendriks, R.W.4    Hoogsteden, H.C.5    Aerts, J.G.6    Hegmans, J.P.7
  • 91
    • 78649598159 scopus 로고    scopus 로고
    • Pivotal advance: tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE catabolism in myeloid cells
    • [91] Eruslanov, E., Daurkin, I., Ortiz, J., Vieweg, J., Kusmartsev, S., Pivotal advance: tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE catabolism in myeloid cells. J. Leukoc. Biol. 88 (2010), 839–848.
    • (2010) J. Leukoc. Biol. , vol.88 , pp. 839-848
    • Eruslanov, E.1    Daurkin, I.2    Ortiz, J.3    Vieweg, J.4    Kusmartsev, S.5
  • 96
    • 84862074482 scopus 로고    scopus 로고
    • MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN
    • [96] Liu, Y., Lai, L., Chen, Q., Song, Y., Xu, S., Ma, F., Wang, X., Wang, J., Yu, H., Cao, X., Wang, Q., MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN. J. Immunol. 188 (2012), 5500–5510.
    • (2012) J. Immunol. , vol.188 , pp. 5500-5510
    • Liu, Y.1    Lai, L.2    Chen, Q.3    Song, Y.4    Xu, S.5    Ma, F.6    Wang, X.7    Wang, J.8    Yu, H.9    Cao, X.10    Wang, Q.11
  • 98
  • 99
    • 79956348160 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL
    • [99] Sinha, P., Chornoguz, O., Clements, V.K., Artemenko, K.A., Zubarev, R.A., Ostrand-Rosenberg, S., Myeloid-derived suppressor cells express the death receptor Fas and apoptose in response to T cell-expressed FasL. Blood 117 (2011), 5381–5390.
    • (2011) Blood , vol.117 , pp. 5381-5390
    • Sinha, P.1    Chornoguz, O.2    Clements, V.K.3    Artemenko, K.A.4    Zubarev, R.A.5    Ostrand-Rosenberg, S.6
  • 100
    • 84952720594 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: critical cells driving immune suppression in the tumor microenvironment
    • [100] Parker, K.H., Beury, D.W., Ostrand-Rosenberg, S., Myeloid-derived suppressor cells: critical cells driving immune suppression in the tumor microenvironment. Adv. Cancer Res. 128 (2015), 95–139.
    • (2015) Adv. Cancer Res. , vol.128 , pp. 95-139
    • Parker, K.H.1    Beury, D.W.2    Ostrand-Rosenberg, S.3
  • 101
    • 84856706929 scopus 로고    scopus 로고
    • Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients
    • [101] Filipazzi, P., Huber, V., Rivoltini, L., Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients. Cancer Immunol. Immunother. 61 (2012), 255–263.
    • (2012) Cancer Immunol. Immunother. , vol.61 , pp. 255-263
    • Filipazzi, P.1    Huber, V.2    Rivoltini, L.3
  • 104
    • 84856453086 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells protect islet transplants by B7-H1 mediated enhancement of T regulatory cells
    • [104] Chou, H.S., Hsieh, C.C., Charles, R., Wang, L., Wagner, T., Fung, J.J., Qian, S., Lu, L.L., Myeloid-derived suppressor cells protect islet transplants by B7-H1 mediated enhancement of T regulatory cells. Transplantation 93 (2012), 272–282.
    • (2012) Transplantation , vol.93 , pp. 272-282
    • Chou, H.S.1    Hsieh, C.C.2    Charles, R.3    Wang, L.4    Wagner, T.5    Fung, J.J.6    Qian, S.7    Lu, L.L.8
  • 106
    • 84884834982 scopus 로고    scopus 로고
    • The role and potential therapeutic application of myeloid-derived suppressor cells in TNBS-induced colitis
    • [106] Guan, Q., Moreno, S., Qing, G., Weiss, C.R., Lu, L., Bernstein, C.N., Warrington, R.J., Ma, Y., Peng, Z., The role and potential therapeutic application of myeloid-derived suppressor cells in TNBS-induced colitis. J. Leukoc. Biol. 94 (2013), 803–811.
    • (2013) J. Leukoc. Biol. , vol.94 , pp. 803-811
    • Guan, Q.1    Moreno, S.2    Qing, G.3    Weiss, C.R.4    Lu, L.5    Bernstein, C.N.6    Warrington, R.J.7    Ma, Y.8    Peng, Z.9
  • 107
    • 84907031164 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as a potential therapy for experimental autoimmune myasthenia gravis
    • [107] Li, Y., Tu, Z., Qian, S., Fung, J.J., Markowitz, S.D., Kusner, L.L., Kaminski, H.J., Lu, L., Lin, F., Myeloid-derived suppressor cells as a potential therapy for experimental autoimmune myasthenia gravis. J. Immunol. 193 (2014), 2127–2134.
    • (2014) J. Immunol. , vol.193 , pp. 2127-2134
    • Li, Y.1    Tu, Z.2    Qian, S.3    Fung, J.J.4    Markowitz, S.D.5    Kusner, L.L.6    Kaminski, H.J.7    Lu, L.8    Lin, F.9
  • 112
    • 84929276485 scopus 로고    scopus 로고
    • Reduced myeloid-derived suppressor cells in the blood and endometrium is associated with early miscarriage
    • [112] Nair, R.R., Sinha, P., Khanna, A., Singh, K., Reduced myeloid-derived suppressor cells in the blood and endometrium is associated with early miscarriage. Am. J. Reprod. Immunol. 73 (2015), 479–486.
    • (2015) Am. J. Reprod. Immunol. , vol.73 , pp. 479-486
    • Nair, R.R.1    Sinha, P.2    Khanna, A.3    Singh, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.