Myeloid-derived suppressor cell function is diminished in aspirin-triggered allergic airway hyperresponsiveness in mice

Journal of Allergy and Clinical Immunology

Volumn 134, Issue 5, 2014, Pages 1163-1174.e16

  Shi, Maohua ^a,b   Shi, Guochao ^c   Tang, Juan ^a   Kong, Deping ^a   Bao, Yao ^c   Xiao, Bing ^a   Zuo, Caojian ^a   Wang, Tai ^a   Wang, Qingsong ^a   Shen, Yujun ^a   Wang, Hui ^a,e   Funk, Colin D ^d   Zhou, Jie ^b,f   Yu, Ying ^a,e  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b Chinese Academy of Sciences   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d QUEEN S UNIVERSITY   (Canada)

^e BEIJING HOSPITAL   (China)

^f SUN YAT SEN UNIVERSITY   (China)

Author keywords

arginase; aspirin intolerant asthma; COX; Myeloid derived suppressor cells; prostaglandin; TH2

Indexed keywords

ACETYLSALICYLIC ACID; ARGINASE; ARGINASE 1; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CXCR2; CHEMOKINE RECEPTOR CXCR3; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLOOXYGENASE 1; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; NITRIC OXIDE; OVALBUMIN; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; ALLERGEN; ARG1 PROTEIN, MOUSE; DIFFERENTIATION ANTIGEN; MEMBRANE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PTGS1 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ADULT; ALLERGIC AIRWAY INFLAMMATION; ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPIRIN EXACERBATED RESPIRATORY DISEASE; BONE MARROW; CELL ACTIVATION; CELL ISOLATION; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INHIBITION; FEMALE; FLOW CYTOMETRY; FORCED EXPIRATORY VOLUME; GENE DELETION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; INTRACELLULAR SIGNALING; LUNG INFILTRATE; LYMPHOCYTE PROLIFERATION; MALE; MOLECULAR PATHOLOGY; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; OVALBUMIN-INDUCED AIRWAY INFLAMMATION; PATHOGENESIS; POLYMORPHONUCLEAR CELL; PROTEIN EXPRESSION; RESPIRATORY TRACT ALLERGY; SUPPRESSOR CELL; TH2 CELL; ANIMAL; BONE MARROW CELL; DRUG EFFECTS; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TOXICITY;

ALLERGENS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, DIFFERENTIATION; ARGINASE; ASPIRIN; ASTHMA, ASPIRIN-INDUCED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOOXYGENASE 1; HUMANS; IMMUNE TOLERANCE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MYELOID CELLS; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SIGNAL TRANSDUCTION; TH2 CELLS;

EID: 84914158918     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.04.035     Document Type: Article

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