Inhibition of AKT signaling by supercritical CO2 extract of mango ginger (Curcuma amada Roxb.) in human glioblastoma cells

Journal of Complementary and Integrative Medicine

Volumn 12, Issue 4, 2015, Pages 307-315

  Ramachandran, Cheppail ^a,b   Portalatin, Gilda ^b   Quirin, Karl W ^c   Escalon, Enrique ^a   Khatib, Ziad ^a   Melnick, Steven J ^a,b  

^a MIAMI CHILDREN'S HOSPITAL   (United States)

^b Dharma Biomedical LLC   (United States)

^c AIR Fertigung Tecbnologie   (Germany)

Author keywords

AKT signaling; cell migration; gene expression; glioblastoma; mango ginger

Indexed keywords

ADENYLATE KINASE; CARBON DIOXIDE; CASPASE 3; CASPASE 9; CURCUMA AMADA EXTRACT; CYTOTOXIC AGENT; HEAT SHOCK PROTEIN 90; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN BNIP3; PROTEIN KINASE B; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG; VASCULOTROPIN; ANTINEOPLASTIC AGENT; MESSENGER RNA; ONCOPROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN CELL; CELL MIGRATION; CONTROLLED STUDY; CURCUMA AMADA; ENZYME INHIBITION; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; HYPOTHALAMUS; IC50; METASTASIS INHIBITION; MIGRATION INHIBITION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TUMOR INVASION; ANTAGONISTS AND INHIBITORS; CURCUMA; DOWN REGULATION; DRUG EFFECTS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYTOTHERAPY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CURCUMA; DOWN-REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; INHIBITORY CONCENTRATION 50; ONCOGENE PROTEIN V-AKT; PHYTOTHERAPY; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84945899470     PISSN: None     EISSN: 15533840     Source Type: Journal    
DOI: 10.1515/jcim-2015-0005     Document Type: Article

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