Activation of spleen tyrosine kinase is required for TNF-α-induced endothelin-1 upregulation in human aortic endothelial cells

FEBS Letters

Volumn 586, Issue 6, 2012, Pages 818-826

  Kim, Yoon Ji ^a   Koo, Tai Yeon ^a   Yang, Won Seok ^a   Han, Nam Jeong ^b   Jeong, Jin Uk ^a   Lee, Sang Koo ^a   Park, Su Kil ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Asan Institute for Life Sciences   (South Korea)

Author keywords

Activator protein 1; Endothelin 1; Reactive oxygen species; Spleen tyrosine kinase; Tumor necrosis factor

Indexed keywords

ENDOTHELIN 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

AORTA; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ET 1 GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; HUMAN; HUMAN CELL; MARKER GENE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; VASCULAR ENDOTHELIUM;

AORTA; ATHEROSCLEROSIS; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIN-1; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84862778498     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.01.055     Document Type: Article

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