A Mitochondrion-targeted antioxidant ameliorates isoflurane-induced cognitive deficits in aging mice

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Wu, Jing ^a,b   Li, Huihui ^a   Sun, Xiaoru ^b   Zhang, Hui ^b   Hao, Shuangying ^a   Ji, Muhuo ^b   Yang, Jianjun ^b   Li, Kuanyu ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CRYOPYRIN; CYTOCHROME C; ELAMIPRETIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; ISOFLURANE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; INHALATION ANESTHETIC AGENT;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; EXPERIMENTAL COGNITIVE TEST; FEAR CONDITIONING TEST; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE METABOLISM; OPEN FIELD TEST; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; MITOCHONDRION;

ADENOSINE TRIPHOSPHATE; AGING; ANESTHETICS, INHALATION; ANIMALS; ANTIOXIDANTS; COGNITION DISORDERS; ISOFLURANE; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; REACTIVE OXYGEN SPECIES;

EID: 84945556096     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0138256     Document Type: Article

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