Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice

Aging Cell

Volumn 12, Issue 5, 2013, Pages 763-771

  Siegel, Michael P ^a,e   Kruse, Shane E ^b   Percival, Justin M ^c,f   Goh, Jorming ^c   White, Collin C ^c   Hopkins, Heather C ^c   Kavanagh, Terrance J ^c   Szeto, Hazel H ^d   Rabinovitch, Peter S ^c   Marcinek, David J ^a,b  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^f UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Mitochondria; Oxidative stress; Sarcopenia; Skeletal muscle

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUTATHIONE; HYDROGEN PEROXIDE; PEPTIDE; SODIUM CHLORIDE; SZETO SCHILLER 31; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ENERGY; CONTROLLED STUDY; ENERGY TRANSFER; FATIGUE; FEMALE; IN VIVO STUDY; MITOCHONDRIAL RESPIRATION; MOUSE; MUSCLE EXERCISE; MUSCLE FUNCTION; MUSCLE STRENGTH; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SKELETAL MUSCLE; TREADMILL EXERCISE;

AGING; MITOCHONDRIA; OXIDATIVE STRESS; SARCOPENIA; SKELETAL MUSCLE;

AGING; ANIMALS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; OXIDATIVE STRESS; SARCOPENIA;

EID: 84883807865     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12102     Document Type: Article

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