Hematopoietic stem and multipotent progenitor cells produce IL-17, IL-21 and other cytokines in response to TLR signals associated with late apoptotic products and augment memory Th17 and Tc17 cells in the bone marrow of normal and lupus mice

Clinical Immunology

Volumn 162, Issue , 2016, Pages 9-26

  Chen, Ching I ^a   Zhang, Li ^a   Datta, Syamal K ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Apoptosis; Bone marrow; Cytokines; Hematopoietic progenitors; Lupus; Memory Th17 Tc17 cells; TLR signals

Indexed keywords

AUTOANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 21; TOLL LIKE RECEPTOR; IL17A PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOIMMUNITY; BONE MARROW; CD8+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEMATOPOIETIC STEM CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; LUPUS ERYTHEMATOSUS; MEGAKARYOBLAST; MEMORY CELL; MOUSE; MULTIPOTENT STEM CELL; NECROPTOSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TH17 CELL; ANIMAL; BLOOD; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; METABOLISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; APOPTOSIS; BONE MARROW; CYTOKINES; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-17; INTERLEUKINS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MULTIPOTENT STEM CELLS; TH17 CELLS; TOLL-LIKE RECEPTORS;

EID: 84945551323     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.10.007     Document Type: Article

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