High-mobility group box 1 protein (HMGB1) neutralization ameliorates experimental autoimmune encephalomyelitis

Journal of Autoimmunity

Volumn 43, Issue , 2013, Pages 32-43

  Robinson, Andrew P ^a   Caldis, Matthew W ^a   Harp, Christopher T ^a   Goings, Gwendolyn E ^a   Miller, Stephen D ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Autoimmune disease; CNS; CSF; DAMP; DTH; EAE; HMGB1; Innate immunity; MBP; MOG; MS; Neuroinflammation; PBMCs; PLP; RAGE; TLR; Tolerance

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN ANTIBODY; MYELIN; NEUTRALIZING ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTIC INFILTRATION; MOUSE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROPHYLAXIS;

ANIMALS; ANTIBODIES, NEUTRALIZING; CD4-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HMGB1 PROTEIN; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MULTIPLE SCLEROSIS; NEUROIMMUNOMODULATION;

EID: 84878368712     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2013.02.005     Document Type: Article

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