Salvianolic acid B inhibits hepatic stellate cell activation through transforming growth factor beta-1 signal transduction pathway in vivo and in vitro

Experimental Biology and Medicine

Volumn 238, Issue 11, 2013, Pages 1284-1296

  Tao, Yan Yan ^a   Wang, Qing Lan ^a,b   Shen, Li ^a,b   Fu, Wen Wei ^a   Liu, Cheng Hai ^a,b,c,d  

^a SHUGUANG HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Shanghai Key Laboratory of Traditional Chinese Clinical Medicine   (China)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d Shanghai Municipal Education Commission   (China)

Author keywords

hepatic stellate cell; liver fibrosis; receptor; Salvianolic acid B; transforming growth factor beta 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; HYDROXYPROLINE; SALVIANOLIC ACID B; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; LIVER FIBROSIS; LIVER HISTOLOGY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; WESTERN BLOTTING;

HEPATIC STELLATE CELL; LIVER FIBROSIS; RECEPTOR; SALVIANOLIC ACID B; TRANSFORMING GROWTH FACTOR BETA-1;

ANIMALS; BENZOFURANS; CELL PROLIFERATION; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; HEPATIC STELLATE CELLS; HYDROXYPROLINE; LIVER CIRRHOSIS; MALE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84887193824     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370213498979     Document Type: Article

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