Polymeric hydrogels as artificial extracellular microenvironments for cancer research

European Polymer Journal

Volumn 72, Issue , 2015, Pages 507-513

  Park, Kyung Min ^a   Gerecht, Sharon ^a  

^a Johns Hopkins University   (United States)

Author keywords

Cancer research; Engineered tumor models; Polymeric hydrogels

Indexed keywords

3D PRINTERS; DISEASES; ENZYME ACTIVITY; POLYMERS; TISSUE CULTURE; TUMORS;

CANCER RESEARCH; EXTRACELLULAR MATRICES; MICRO /NANO FABRICATIONS; MICRO-FLUIDIC DEVICES; POLYMERIC HYDROGELS; THREEDIMENSIONAL (3-D); TUMOR MICROENVIRONMENTS; TUMOR MODELS;

HYDROGELS;

EID: 84945487774     PISSN: 00143057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpolymj.2015.06.030     Document Type: Article

References (49)

1. C.L. Arteaga, P.C. Adamson, J.A. Engelman, M. Foti, R.B. Gaynor, S.G. Hilsenbeck, and et al. AACR cancer progress report 2014 Clin. Cancer Res. 20 19 Suppl 2014 S1 S112
2. K.R. Yabroff, J. Lund, D. Kepka, and A. Mariotto Economic burden of cancer in the United States: estimates, projections, and future research Cancer Epidemiol., Biomark. Prev. 20 10 2011 2006 2014
3. D.F. Quail, and J.A. Joyce Microenvironmental regulation of tumor progression and metastasis Nat. Med. 19 11 2013 1423 1437
4. S.M. Weis, and D.A. Cheresh Tumor angiogenesis: molecular pathways and therapeutic targets Nat. Med. 17 11 2011 1359 1370
5. D. Ackerman, and M.C. Simon Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment Trends Cell Biol. 24 8 2014 472 478
6. B. Keith, R.S. Johnson, and M.C. Simon HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression Nat. Rev. Cancer 12 1 2012 9 22
7. K.M. Charoen, B. Fallica, Y.L. Colson, M.H. Zaman, and M.W. Grinstaff Embedded multicellular spheroids as a biomimetic 3D cancer model for evaluating drug and drug-device combinations Biomaterials 35 7 2014 2264 2271
8. Y.I. Shen, H.E. Abaci, Y. Krupsi, L.C. Weng, J.A. Burdick, and S. Gerecht Hyaluronic acid hydrogel stiffness and oxygen tension affect cancer cell fate and endothelial sprouting Biomater. Sci. 2 5 2014 655 665
9. E.Y. Tokuda, J.L. Leight, and K.S. Anseth Modulation of matrix elasticity with PEG hydrogels to study melanoma drug responsiveness Biomaterials 35 14 2014 4310 4318
10. S. Paget The distribution of secondary growths in cancer of the breast. 1889 Cancer Metastasis Rev. 8 2 1989 98 101
11. M.R. Junttila, and F.J. de Sauvage Influence of tumour micro-environment heterogeneity on therapeutic response Nature 501 7467 2013 346 354
12. A. Rizki, V.M. Weaver, S.Y. Lee, G.I. Rozenberg, K. Chin, C.A. Myers, and et al. A human breast cell model of preinvasive to invasive transition Cancer Res. 68 5 2008 1378 1387
13. S.I. Fraley, Y. Feng, R. Krishnamurthy, D.H. Kim, A. Celedon, G.D. Longmore, and et al. A distinctive role for focal adhesion proteins in three-dimensional cell motility Nat. Cell Biol. 12 6 2010 598 604
14. V. Seewaldt ECM stiffness paves the way for tumor cells Nat. Med. 20 4 2014 332 333
15. T.S. Eisinger-Mathason, M. Zhang, Q. Qiu, N. Skuli, M.S. Nakazawa, T. Karakasheva, and et al. Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis Cancer Discov. 3 10 2013 1190 1205
16. D.M. Gilkes, P. Chaturvedi, S. Bajpai, C.C. Wong, H. Wei, S. Pitcairn, and et al. Collagen prolyl hydroxylases are essential for breast cancer metastasis Cancer Res. 73 11 2013 3285 3296
17. S. Kumar, and V.M. Weaver Mechanics, malignancy, and metastasis: the force journey of a tumor cell Cancer Metastasis Rev. 28 1-2 2009 113 127
18. D. Fukumura, and R.K. Jain Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize J. Cell. Biochem. 101 4 2007 937 949
19. P.P. Provenzano, D.R. Inman, K.W. Eliceiri, J.G. Knittel, L. Yan, C.T. Rueden, and et al. Collagen density promotes mammary tumor initiation and progression BMC Med. 6 2008 11
20. K. Kessenbrock, V. Plaks, and Z. Werb Matrix metalloproteinases: regulators of the tumor microenvironment Cell 141 1 2010 52 67
21. S.D. Shapiro Matrix metalloproteinase degradation of extracellular matrix: biological consequences Curr. Opin. Cell Biol. 10 5 1998 602 608
22. H. Sato, T. Takino, Y. Okada, J. Cao, A. Shinagawa, E. Yamamoto, and et al. A matrix metalloproteinase expressed on the surface of invasive tumour cells Nature 370 6484 1994 61 65
23. N.E. Sounni, and A. Noel Targeting the tumor microenvironment for cancer therapy Clin. Chem. 59 1 2013 85 93
24. L.A. Shuman Moss, S. Jensen-Taubman, and W.G. Stetler-Stevenson Matrix metalloproteinases: changing roles in tumor progression and metastasis Am. J. Pathol. 181 6 2012 1895 1899
25. D.W. Infanger, M.E. Lynch, and C. Fischbach Engineered culture models for studies of tumor-microenvironment interactions Annu. Rev. Biomed. Eng. 15 2013 29 53
26. J.W. Pollard Tumour-educated macrophages promote tumour progression and metastasis Nat. Rev. Cancer 4 1 2004 71 78
27. D. Seliktar Designing cell-compatible hydrogels for biomedical applications Science 336 6085 2012 1124 1128
28. J.J. Rice, M.M. Martino, L. De Laporte, F. Tortelli, P.S. Briquez, and J.A. Hubbell Engineering the regenerative microenvironment with biomaterials Adv. Healthcare Mater. 2 1 2013 57 71
29. K.E. Kadler, C. Baldock, J. Bella, and R.P. Boot-Handford Collagens at a glance J. Cell Sci. 120 12 2007 1955 1958
30. A. Ganguly, H.L. Yang, and F. Cabral Paclitaxel-dependent cell lines reveal a novel drug activity Mol. Cancer Ther. 9 11 2010 2914 2923
31. I.A. Santana, J.A. De Oliveira, A.A. Amaral, L. Testa, L.G. Landeiro, R.L.D. Costa, and et al. Feasibility of two schedules of weekly paclitaxel as (neo)adjuvant treatment for patients (PTS) with HER2-negative breast cancer (BC) in the Brazilian community setting J. Clin. Oncol. 30 27 2012
32. J.A. Sparano, M.L. Wang, S. Martino, V. Jones, E.A. Perez, T. Saphner, and et al. Weekly paclitaxel in the adjuvant treatment of breast cancer (vol. 358, p. 1663, 2008) New Engl. J. Med. 360 16 2009 1685-1685
33. A.H. Colby, Y.L. Colson, and M.W. Grinstaff Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles Nanoscale 5 8 2013 3496 3504
34. H. Kennecke, R. Yerushalmi, R. Woods, M.C. Cheang, D. Voduc, C.H. Speers, and et al. Metastatic behavior of breast cancer subtypes J. Clin. Oncol. 28 20 2010 3271 3277
35. L.E. Barney, E.C. Dandley, L.E. Jansen, N.G. Reich, A.M. Mercurio, and S.R. Peyton A cell-ECM screening method to predict breast cancer metastasis Integr. Biol. (Camb.) 7 2 2015 198 212
36. B.P. Toole Hyaluronan: from extracellular glue to pericellular cue Nat. Rev. Cancer 4 7 2004 528 539
37. B.P. Toole, T.N. Wight, and M.I. Tammi Hyaluronan-cell interactions in cancer and vascular disease J. Biol. Chem. 277 7 2002 4593 4596
38. M. Yu, S. Jambhrunkar, P. Thorn, J. Chen, W. Gu, and C. Yu Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells Nanoscale 5 1 2013 178 183
39. S. Pedron, E. Becka, and B.A. Harley Regulation of glioma cell phenotype in 3D matrices by hyaluronic acid Biomaterials 34 30 2013 7408 7417
40. X. Xu, L.A. Gurski, C. Zhang, D.A. Harrington, M.C. Farach-Carson, and X. Jia Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids Biomaterials 33 35 2012 9049 9060
41. X. Xu, C.R. Sabanayagam, D.A. Harrington, M.C. Farach-Carson, and X. Jia A hydrogel-based tumor model for the evaluation of nanoparticle-based cancer therapeutics Biomaterials 35 10 2014 3319 3330
42. B.J. Gill, D.L. Gibbons, L.C. Roudsari, J.E. Saik, Z.H. Rizvi, J.D. Roybal, and et al. A synthetic matrix with independently tunable biochemistry and mechanical properties to study epithelial morphogenesis and EMT in a lung adenocarcinoma model Cancer Res. 72 22 2012 6013 6023
43. C. Wang, X. Tong, and F. Yang Bioengineered 3D brain tumor model to elucidate the effects of matrix stiffness on glioblastoma cell behavior using PEG-based hydrogels Mol. Pharm. 11 7 2014 2115 2125
44. S. Bersini, J.S. Jeon, G. Dubini, C. Arrigoni, S. Chung, J.L. Charest, and et al. A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone Biomaterials 35 8 2014 2454 2461
45. T.Q. Huang, X. Qu, J. Liu, and S. Chen 3D printing of biomimetic microstructures for cancer cell migration Biomed. Microdev. 16 1 2014 127 132
46. A.D. Wong, and P.C. Searson Live-cell imaging of invasion and intravasation in an artificial microvessel platform Cancer Res. 74 17 2014 4937 4945
47. S. Pedron, E. Becka, and B.A. Harley Spatially gradated hydrogel platform as a 3D engineered tumor microenvironment Adv. Mater. 27 9 2015 1567 1572
48. S.V. Murphy, and A. Atala 3D bioprinting of tissues and organs Nat. Biotechnol. 32 8 2014 773 785
49. J.S. Miller, K.R. Stevens, M.T. Yang, B.M. Baker, D.H. Nguyen, D.M. Cohen, and et al. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues Nat. Mater. 11 9 2012 768 774