Live-cell imaging of invasion and intravasation in an artificial microvessel platform

Cancer Research

Volumn 74, Issue 17, 2014, Pages 4937-4945

  Wong, Andrew D ^a   Searson, Peter C ^a  

^a Whiting School of Engineering   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSTIC IMAGING; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; MICROVASCULATURE; PATHOLOGY; PHYSIOLOGY; PROCEDURES; TUMOR CELL LINE; TUMOR INVASION; TUMOR MICROENVIRONMENT;

CELL LINE, TUMOR; DIAGNOSTIC IMAGING; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; HUMANS; MICROVESSELS; NEOPLASM INVASIVENESS; TUMOR MICROENVIRONMENT;

EID: 84907053817     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-1042     Document Type: Article

References (41)

1. Fidler IJ. Timeline - The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003;3: 453-8.
2. Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002;2:563-72.
3. Steeg PS. Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 2006;12:895-904.
4. Butler JM, Kobayashi H, Rafii S. Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors. Nat Rev Cancer 2010;10:138-46.
5. Ghajar CM, Peinado H, Mori H, Matei IR, Evason KJ, Brazier H, et al. The perivascular niche regulates breast tumour dormancy. Nat Cell Biol 2013;15:807-17.
6. Fraley SI, Feng Y, Krishnamurthy R, Kim DH, Celedon A, Longmore GD, et al. A distinctive role for focal adhesion proteins in three-dimensional cell motility. Nat Cell Biol 2010;12:598-604.
7. Friedl P, Wolf K. Tumour-cell invasion and migration: Diversity and escape mechanisms. Nat Rev Cancer 2003;3:362-74.
8. Chrobak KM, Potter DR, Tien J. Formation of perfused, functional microvascular tubes in vitro. Microvasc Res 2006;71:185-96.
9. Lagace R, Grimaud JA, Schurch W, Seemayer TA. Myofibroblastic stromal reaction in carcinoma of the breast: variations of collagenous matrix and structural glycoproteins. Virchows Arch A Pathol Anat Histopathol 1985;408:49-59.
10. Cross VL, Zheng Y, Won Choi N, Verbridge SS, Sutermaster BA, Bonassar LJ, et al. Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro. Biomaterials 2010;31:8596-607.
11. Yuan Y, Chilian WM, Granger HJ, Zawieja DC. Permeability to albumin in isolated coronary venules. Am J Physiol 1993;265:H543-52.
12. Huxley VH, Curry FE, Adamson RH. Quantitative fluorescence microscopy on single capillaries: alpha-lactalbumin transport. Am J Physiol 1987;252:H188-97.
13. Taylor ZJ, Gurka R, Kopp GA, Liberzon A. Long-duration time-resolved piv to study unsteady aerodynamics. IEEE T Instrum Meas 2010;59: 3262-9.
14. Hoffman RM. The multiple uses of fluorescent proteins to visualize cancer in vivo. Nat Rev Cancer 2005;5:796-806.
15. RaubCB, Suresh V, Krasieva T, Lyubovitsky J, Mih JD,PutnamAJ, et al. Noninvasive assessmentof collagen gel microstructureandmechanics using multiphoton microscopy. Biophys J 2007;92:2212-22.
16. Condeelis J, Segall JE. Intravital imaging of cell movement in tumours. Nat Rev Cancer 2003;3:921-30.
17. Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K, et al. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 2007;9:1392-400.
18. Sabeh F, Shimizu-Hirota R, Weiss SJ. Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited. J Cell Biol 2009;185:11-9.
19. Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, et al. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol 2007;9:893-904.
20. Roussos ET, Condeelis JS, Patsialou A. Chemotaxis in cancer. Nat Rev Cancer 2011;11:573-87.
21. Brabek J, Mierke CT, Rosel D, Vesely P, Fabry B. The role of the tissue microenvironment in the regulation of cancer cell motility and invasion. Cell Commun Signal 2010;8:22.
22. Bailly M, Yan L, Whitesides GM, Condeelis JS, Segall JE. Regulation of protrusion shape and adhesion to the substratum during chemotactic responses of mammalian carcinoma cells. Exp Cell Res 1998;241: 285-99.
23. Franses JW, Baker AB, Chitalia VC, Edelman ER. Stromal endothelial cells directly influence cancer progression. Sci Transl Med 2011;3: 66ra5.
24. Huber AR, Weiss SJ. Disruption of the subendothelial basement membrane during neutrophil diapedesis in an in vitro construct of a blood vessel wall. J Clin Invest 1989;83:1122-36.
25. Iozzo RV, Sanderson RD. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis. J Cell Mol Med 2011;15: 1013-31.
26. Zervantonakis IK,Hughes-Alford SK, Charest JL, Condeelis JS, Gertler FB, Kamm RD. Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function. Proc Natl Acad SciUS A 2012;109:13515-20.
27. Lee TH, Avraham HK, Jiang S, Avraham S. Vascular endothelial growth factor modulates the transendothelial migration of MDAMB- 231 breast cancer cells through regulation of brain microvascular endothelial cell permeability. J Biol Chem 2003;278: 5277-84.
28. Gerhardt H, Semb H. Pericytes: gatekeepers in tumour cell metastasis? J Mol Med 2008;86:135-44.
29. Matzke R, Jacobson K, Radmacher M. Direct, high-resolution measurement of furrow stiffening during division of adherent cells. Nat Cell Biol 2001;3:607-10.
30. Price JT, Tiganis T, Agarwal A, Djakiew D, Thompson EW. Epidermal growth factor promotes MDA-MB-231 breast cancer cell migration through a phosphatidylinositol 30-kinase and phospholipase C-dependent mechanism. Cancer Res 1999;59:5475-8.
31. Brantley-Sieders DM, Dunaway CM, Rao M, Short S, Hwang Y, Gao Y, et al. Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium. Cancer Res 2011;71:976-87.
32. Chung S, Sudo R, Mack PJ, Wan CR, Vickerman V, Kamm RD. Cell migration into scaffolds under co-culture conditions in a microfluidic platform. Lab Chip 2009;9:269-75.
33. HellstromM, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 2007;445:776-80.
34. De Smet F, Segura I, De Bock K, Hohensinner PJ, Carmeliet P. Mechanisms of vessel branching: filopodia on endothelial tip cells lead the way. Arterioscler Thromb Vasc Biol 2009;29:639-49.
35. Burden-Gulley SM, Qutaish MQ, Sullivant KE, Lu H, Wang J, Craig SE, et al. Novel cryo-imaging of the glioma tumor microenvironment reveals migration and dispersal pathways in vivid three-dimensional detail. Cancer Res 2011;71:5932-40.
36. Baluk P, Hashizume H, McDonald DM. Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 2005;15: 102-11.
37. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74.
38. Buchanan CF, Voigt EE, Szot CS, Freeman JW, Vlachos PP, Rylander MN. Three-dimensional microfluidic collagen hydrogels for investigating flow-mediated tumor-endothelial signaling and vascular organization. Tissue Eng Part C Methods 2014;20:64-75.
39. Shieh AC, Swartz MA. Regulation of tumor invasion by interstitial fluid flow. Phys Biol 2011;8:015012.
40. Song JW, Munn LL. Fluid forces control endothelial sprouting. Proc Natl Acad Sci U S A 2011;108:15342-7.
41. Provenzano PP, Inman DR, Eliceiri KW, Knittel JG, Yan L, Rueden CT, et al. Collagen density promotes mammary tumor initiation and progression. BMC Med 2008;6:11.