Reversible behavioral phenotypes in a conditional mouse model of TDP-43 proteinopathies

Journal of Neuroscience

Volumn 34, Issue 46, 2014, Pages 15244-15259

  Alfieri, Julio A ^a   Pino, Natalia S ^a   Igaz, Lionel M ^a  

^a Buenos Aires   (Argentina)

Author keywords

Behavioral phenotypes; Frontotemporal dementia; Neurodegeneration; Proteinopathies; TDP 43; Transgenic mice

Indexed keywords

DOXYCYCLINE; TAR DNA BINDING PROTEIN; DNA BINDING PROTEIN; TDP-43 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR GENETICS; COGNITIVE DEFECT; EXPERIMENTAL HYPERACTIVITY; FEMALE; GENE INDUCTION; GRIP STRENGTH TEST; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MALE; MOTOR DYSFUNCTION; MOUSE; NERVE DEGENERATION; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; OPEN FIELD TEST; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSIBLE BEHAVIORAL PHENOTYPE; ROTAROD TEST; SOCIAL INTERACTION TEST; STEP-THROUGH PASSIVE AVOIDANCE TEST; TDP 43 PROTEINOPATHY; Y-MAZE TEST; ANIMAL; COMPLICATION; DISEASE MODEL; DOWN REGULATION; ENDOPHENOTYPE; FRONTOTEMPORAL DEMENTIA; GENETICS; HYPERKINESIA; MAZE TEST; MOTOR NEURON DISEASE; PHYSIOLOGY; PSYCHOLOGY; RECOGNITION; SOCIAL BEHAVIOR; SPASTICITY; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DOWN-REGULATION; ENDOPHENOTYPES; FRONTOTEMPORAL DEMENTIA; HYPERKINESIS; MALE; MAZE LEARNING; MICE; MICE, TRANSGENIC; MOTOR NEURON DISEASE; MUSCLE SPASTICITY; RECOGNITION (PSYCHOLOGY); ROTAROD PERFORMANCE TEST; SOCIAL BEHAVIOR; TDP-43 PROTEINOPATHIES; UP-REGULATION;

EID: 84909953328     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1918-14.2014     Document Type: Article

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