-
1
-
-
85041547121
-
ICEBERG3
-
26 February
-
Kaye SB. ICEBERG3. http://clinicaltrials.gov/show/NCT00628251. ClinicalTrials.gov, 26 February 2008.
-
(2008)
-
-
Kaye, S.B.1
-
2
-
-
84863010984
-
Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer
-
Kaye SB, Lubinski J, Matulonis U, Ang J E, Gourley C, Karlan BY, et al. Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer. Journal of Clinical Oncology 2012;30(4):372-9.
-
(2012)
Journal of Clinical Oncology
, vol.30
, Issue.4
, pp. 372-379
-
-
Kaye, S.B.1
Lubinski, J.2
Matulonis, U.3
Ang, J.E.4
Gourley, C.5
Karlan, B.Y.6
-
3
-
-
84927535927
-
Randomized trial of oral cyclophosphamide and veliparib in high-grade serous ovarian, primary peritoneal, or fallopian tube cancers, or BRCA-mutant ovarian cancer
-
Kummar S, Fleming GF, Oza AM, Sullivan DM, Gandara DR, Naughton M, et al. Randomized trial of oral cyclophosphamide and veliparib in high-grade serous ovarian, primary peritoneal, or fallopian tube cancers, or BRCA-mutant ovarian cancer. Clinical Cancer Research 2015;14:2562. [DOI: 10.1158/1078-0432.CCR-14-2565]
-
(2015)
Clinical Cancer Research
, vol.14
, pp. 2562
-
-
Kummar, S.1
Fleming, G.F.2
Oza, A.M.3
Sullivan, D.M.4
Gandara, D.R.5
Naughton, M.6
-
4
-
-
84898455021
-
Randomized trial of oral cyclophosphamide with or without veliparib (V), an oral poly (ADP-ribose) polymerase (PARP) inhibitor, in patients with recurrent BRCA-positive ovarian, or primary peritoneal or high-grade serous ovarian carcinoma. 2012 ASCO Annual Meeting
-
Kummar S, Oza A, Fleming G, Sullivan D, Gandara D, Erlichman C, et al. Randomized trial of oral cyclophosphamide with or without veliparib (V), an oral poly (ADP-ribose) polymerase (PARP) inhibitor, in patients with recurrent BRCA-positive ovarian, or primary peritoneal or high-grade serous ovarian carcinoma. 2012 ASCO Annual Meeting. Journal of Clinical Oncology 2012;30(15 Suppl):5020. [: http://meetinglibrary.asco.org/content/98169-114]
-
(2012)
Journal of Clinical Oncology
, vol.30
, Issue.15
, pp. 5020
-
-
Kummar, S.1
Oza, A.2
Fleming, G.3
Sullivan, D.4
Gandara, D.5
Erlichman, C.6
-
5
-
-
85041506358
-
Assessment of efficacy of AZD2281 in platinum sensitive relapsed serous ovarian cancer
-
12 September
-
Ledermann J. Assessment of efficacy of AZD2281 in platinum sensitive relapsed serous ovarian cancer. http://clinicaltrials.gov/show/NCT00753545 12 September 2008.
-
(2008)
-
-
Ledermann, J.1
-
6
-
-
85041534486
-
Phase 2 randomized placebo-controlled study of olaparib (AZD2281) in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC)
-
Ledermann J, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, Scott C, Meier W, Shapira Frommer R, Safra T, Matei D, Macpherson E, Watkins C, Carmichael J, Matulonis U. Phase 2 randomized placebo-controlled study of olaparib (AZD2281) in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC). International journal of gynecological cancer. 2011; Vol. 21 (S13).
-
(2011)
International journal of gynecological cancer
, vol.21
-
-
Ledermann, J.1
Harter, P.2
Gourley, C.3
Friedlander, M.4
Vergote, I.5
Rustin, G.6
Scott, C.7
Meier, W.8
Shapira Frommer, R.9
Safra, T.10
Matei, D.11
Macpherson, E.12
Watkins, C.13
Carmichael, J.14
Matulonis, U.15
-
7
-
-
84903547236
-
Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
-
Ledermann J, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, Scott CL, Meier W, Shapira-Frommer R, Safra T, Matei D, Fielding A, Spencer S, Dougherty B, Orr M, Hodgson D, Barrett JC, Matulonis U. Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. Lancet oncology 2014;15(8):852-861.
-
(2014)
Lancet oncology
, vol.15
, Issue.8
, pp. 852-861
-
-
Ledermann, J.1
Harter, P.2
Gourley, C.3
Friedlander, M.4
Vergote, I.5
Rustin, G.6
Scott, C.L.7
Meier, W.8
Shapira-Frommer, R.9
Safra, T.10
Matei, D.11
Fielding, A.12
Spencer, S.13
Dougherty, B.14
Orr, M.15
Hodgson, D.16
Barrett, J.C.17
Matulonis, U.18
-
8
-
-
84859523588
-
Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer
-
Ledermann J, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, et al. Olaparib maintenance therapy in platinum-sensitive relapsed ovarian cancer. New England Journal of Medicine 2012;366(15):1382-92.
-
(2012)
New England Journal of Medicine
, vol.366
, Issue.15
, pp. 1382-1392
-
-
Ledermann, J.1
Harter, P.2
Gourley, C.3
Friedlander, M.4
Vergote, I.5
Rustin, G.6
-
9
-
-
84925853373
-
Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
-
Ledermann J, Harter P, Gourley C, Friedlander M, Vergote I, Rustin G, Scott CL, Meier W, Shapira-Frommer R, Safra T, Matei D, Fielding A, Spencer S, Dougherty B, Orr M, Hodgson D, Barrett JC, Matulonis U. Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. Obstetrical & gynecological survey 2015;69((10)):594-596.
-
(2015)
Obstetrical & gynecological survey
, vol.69
, Issue.10
, pp. 594-596
-
-
Ledermann, J.1
Harter, P.2
Gourley, C.3
Friedlander, M.4
Vergote, I.5
Rustin, G.6
Scott, C.L.7
Meier, W.8
Shapira-Frommer, R.9
Safra, T.10
Matei, D.11
Fielding, A.12
Spencer, S.13
Dougherty, B.14
Orr, M.15
Hodgson, D.16
Barrett, J.C.17
Matulonis, U.18
-
10
-
-
80053135643
-
Phase II randomized placebo-controlled study of olaparib (AZD2281) in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC)
-
Ledermann JA, Harter P, Gourley C, Friedlander M, Vergote IB, Rustin GJS, Scott C, Meier W, Shapira-Frommer R, Safra T, Matei D, Macpherson E, Watkins C, Carmichael J, Matulonis U. Phase II randomized placebo-controlled study of olaparib (AZD2281) in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC). Journal of clinical oncology. 2011; Vol. 29.
-
(2011)
Journal of clinical oncology
, vol.29
-
-
Ledermann, J.A.1
Harter, P.2
Gourley, C.3
Friedlander, M.4
Vergote, I.B.5
Rustin, G.J.S.6
Scott, C.7
Meier, W.8
Shapira-Frommer, R.9
Safra, T.10
Matei, D.11
Macpherson, E.12
Watkins, C.13
Carmichael, J.14
Matulonis, U.15
-
11
-
-
85041519051
-
Analysis of intermediate clinical endpoints from a Phase II trial of olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC)
-
Gynecologic oncology 2014;Conference: 45th Annual Meeting on Women's Cancer of the Society of Gynecologic Oncology, SGO 2014 Tampa, FL United States. Conference Start: 20140322 Conference End: 20140325. Conference Publication:(var.pagings)
-
Matulonis UA, Harter P, Gourley C, Friedlander M, Vergote IB, Rustin GJS, Fielding A, Spencer S, Ho TW, Ledermann JA. Analysis of intermediate clinical endpoints from a Phase II trial of olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer (PSR SOC). Gynecologic oncology 2014;Conference: 45th Annual Meeting on Women's Cancer of the Society of Gynecologic Oncology, SGO 2014 Tampa, FL United States. Conference Start: 20140322 Conference End: 20140325. Conference Publication:(var.pagings):54-55. 2014.
-
(2014)
, pp. 54-55
-
-
Matulonis, U.A.1
Harter, P.2
Gourley, C.3
Friedlander, M.4
Vergote, I.B.5
Rustin, G.J.S.6
Fielding, A.7
Spencer, S.8
Ho, T.W.9
Ledermann, J.A.10
-
12
-
-
84924760015
-
Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase II trial
-
Oza A, Cibula D, Oaknin Benzaquen A, Poole C, Mathijssen RHJ, Sonke GS, et al. Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase II trial. Lancet Oncology 2015;; Vol. 16, issue 1:87-97.
-
(2015)
Lancet Oncology
, vol.16
, Issue.1
, pp. 87-97
-
-
Oza, A.1
Cibula, D.2
Oaknin Benzaquen, A.3
Poole, C.4
Mathijssen, R.H.J.5
Sonke, G.S.6
-
13
-
-
84866768008
-
Olaparib plus paclitaxel plus carboplatin (P/C) followed by olaparib maintenance treatment in patients (pts) with platinum-sensitive recurrent serous ovarian cancer (PSR SOC): A randomized, open-label phase II study
-
Oza AM, Cibula D, Oaknin A, Poole CJ, Mathijssen RHJ, Sonke GS, et al. Olaparib plus paclitaxel plus carboplatin (P/C) followed by olaparib maintenance treatment in patients (pts) with platinum-sensitive recurrent serous ovarian cancer (PSR SOC): A randomized, open-label phase II study. Journal of Clinical Oncology 2012;30(15 Suppl):5001. [: http://meeting.ascopubs.org/cgi/content/abstract/30/15_suppl/5001]
-
(2012)
Journal of Clinical Oncology
, vol.30
, Issue.15
, pp. 5001
-
-
Oza, A.M.1
Cibula, D.2
Oaknin, A.3
Poole, C.J.4
Mathijssen, R.H.J.5
Sonke, G.S.6
-
14
-
-
84924782564
-
Olaparib plus chemotherapy, followed by maintenance monotherapy, in women with platinum-sensitive recurrent serous ovarian cancer (PSR SOC): BRCA1/2 mutation (BRCAm) and interim overall survival analyses
-
Oza AM, Cibula D, Oaknin Benzaquen A, Poole CJ, Mathijssen RHJ, et al. Olaparib plus chemotherapy, followed by maintenance monotherapy, in women with platinum-sensitive recurrent serous ovarian cancer (PSR SOC): BRCA1/2 mutation (BRCAm) and interim overall survival analyses. European Journal of Cancer 2013;49 Suppl 2:S712-S3.
-
(2013)
European Journal of Cancer
, vol.49
, pp. S712-S7S3
-
-
Oza, A.M.1
Cibula, D.2
Oaknin Benzaquen, A.3
Poole, C.J.4
Mathijssen, R.H.J.5
-
15
-
-
49249119415
-
A synthetic lethal therapeutic approach: Poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair
-
Ashworth A. A synthetic lethal therapeutic approach: Poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. Journal of Clinical Oncology 2008;26(22):3785-90.
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.22
, pp. 3785-3790
-
-
Ashworth, A.1
-
16
-
-
68149161777
-
Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer
-
Audeh MW, Penson RT, Friedlander M. Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer. Journal of Clinical Oncology (Meeting Abstracts) 2009;27(15S):5500.
-
(2009)
Journal of Clinical Oncology (Meeting Abstracts)
, vol.27
, Issue.15
, pp. 5500
-
-
Audeh, M.W.1
Penson, R.T.2
Friedlander, M.3
-
17
-
-
77955039099
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
-
Audeh MW, Carmichael J, Penson RT, Friedlander M, Powell B, Bell-McGuinn KM, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 2010;376(9737):245-51.
-
(2010)
Lancet
, vol.376
, Issue.9737
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
Friedlander, M.4
Powell, B.5
Bell-McGuinn, K.M.6
-
18
-
-
84874821284
-
New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential
-
Banerjee S, Kaye SB. New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential. Clinical Cancer Research 2013;19(5):961-8.
-
(2013)
Clinical Cancer Research
, vol.19
, Issue.5
, pp. 961-968
-
-
Banerjee, S.1
Kaye, S.B.2
-
19
-
-
84880811116
-
Olaparib: a promising PARP inhibitor in ovarian cancer therapy
-
Chen Y, Zhang L, Hao Q. Olaparib: a promising PARP inhibitor in ovarian cancer therapy. Archives of Gynecology and Obstetrics 2013;288(2):367-74.
-
(2013)
Archives of Gynecology and Obstetrics
, vol.288
, Issue.2
, pp. 367-374
-
-
Chen, Y.1
Zhang, L.2
Hao, Q.3
-
20
-
-
84927927853
-
A phase II evaluation of the potent, highly selective PARP inhibitor veliparib in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer in patients who carry a germline BRCA1 or BRCA2 mutation - A Gynecologic Oncology Group study
-
Gynecologic oncology. 45th Annual Meeting on Women's Cancer of the Society of Gynecologic Oncology, SGO 2014 Tampa, FL United States. Conference Start: 20140322 Conference End: 20140325. Conference Publication
-
Coleman RL, Sill M, Aghajanian C, Gray HJ, Tewari KS, Rubin SC, Rutherford TJ, Chan JK, Chen HX, Swisher EM. A phase II evaluation of the potent, highly selective PARP inhibitor veliparib in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer in patients who carry a germline BRCA1 or BRCA2 mutation - A Gynecologic Oncology Group study. Gynecologic oncology. 2014; Vol. 45th Annual Meeting on Women's Cancer of the Society of Gynecologic Oncology, SGO 2014 Tampa, FL United States. Conference Start: 20140322 Conference End: 20140325. Conference Publication:56-57.
-
(2014)
, pp. 56-57
-
-
Coleman, R.L.1
Sill, M.2
Aghajanian, C.3
Gray, H.J.4
Tewari, K.S.5
Rubin, S.C.6
Rutherford, T.J.7
Chan, J.K.8
Chen, H.X.9
Swisher, E.M.10
-
21
-
-
53149147473
-
The potential of PARP inhibitors in genetic breast and ovarian cancers
-
Drew Y, Calvert H. The potential of PARP inhibitors in genetic breast and ovarian cancers. Annals of the New York Academy of Science 2008;1138:136-45.
-
(2008)
Annals of the New York Academy of Science
, vol.1138
, pp. 136-145
-
-
Drew, Y.1
Calvert, H.2
-
22
-
-
34249024488
-
Phase I pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of a small molecule inhibitor of Poly ADP-Ribose Polymerase (PARP), KU-0059436 (Ku) in patients (p) with advanced tumours
-
Fong PC, Spicer J, Reade S. Phase I pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of a small molecule inhibitor of Poly ADP-Ribose Polymerase (PARP), KU-0059436 (Ku) in patients (p) with advanced tumours. Journal of Clinical Oncology (Meeting Abstracts) 2006;24(18 Suppl):3022.
-
(2006)
Journal of Clinical Oncology (Meeting Abstracts)
, vol.24
, Issue.18
, pp. 3022
-
-
Fong, P.C.1
Spicer, J.2
Reade, S.3
-
23
-
-
55749096953
-
AZD2281 (KU-0059436), a PARP (poly ADP-ribose polymerase) inhibitor with single agent anticancer activity in patients with BRCA deficient ovarian cancer: Results from a phase I study
-
Fong PC, Boss DS, Carden CP. AZD2281 (KU-0059436), a PARP (poly ADP-ribose polymerase) inhibitor with single agent anticancer activity in patients with BRCA deficient ovarian cancer: Results from a phase I study. Journal of Clinical Oncology (Meeting Abstracts) 2008;26(15 Suppl):5510.
-
(2008)
Journal of Clinical Oncology (Meeting Abstracts)
, vol.26
, Issue.15
, pp. 5510
-
-
Fong, P.C.1
Boss, D.S.2
Carden, C.P.3
-
24
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC, Boss DS, Yap TA. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. New England Journal of Medicine 2009;361(2):123-34.
-
(2009)
New England Journal of Medicine
, vol.361
, Issue.2
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
-
25
-
-
80052389761
-
Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: A phase 2, multicentre, open-label, non-randomised study
-
Gelmon KA, Tischkowitz M, Mackay H, Swenerton K, Robidoux A, Tonkin K, et al. Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: A phase 2, multicentre, open-label, non-randomised study. Lancet Oncology 2011;12(9):852-61.
-
(2011)
Lancet Oncology
, vol.12
, Issue.9
, pp. 852-861
-
-
Gelmon, K.A.1
Tischkowitz, M.2
Mackay, H.3
Swenerton, K.4
Robidoux, A.5
Tonkin, K.6
-
26
-
-
39749166975
-
DNA repair pathways as targets for cancer therapy
-
Helleday T, Petermann E, Lundin C, Hodgson B, Sharma RA. DNA repair pathways as targets for cancer therapy. Nature Reviews Cancer 2008;8(3):193-204.
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.3
, pp. 193-204
-
-
Helleday, T.1
Petermann, E.2
Lundin, C.3
Hodgson, B.4
Sharma, R.A.5
-
27
-
-
85041526409
-
Biomarker correlates from the randomized phase 2 trial of the PARP inhibitor olaparib (O) with or without the antiangiogenic TKI cediranib (C) in recurrent platinum-sensitive ovarian cancer (NCT01116648)
-
suppl.
-
Lee J-M, Liu J, Choyke PL, Elbuluk O, Turkbey IB, Trepel JB, Lee M-J, Cao L, Houston ND, Gordon N, Figg WD, Barry WT, Matulonis U, Birrer MJ, Ivy P, Kohn EC. Biomarker correlates from the randomized phase 2 trial of the PARP inhibitor olaparib (O) with or without the antiangiogenic TKI cediranib (C) in recurrent platinum-sensitive ovarian cancer (NCT01116648). Journal of clinical oncology. 2014; Vol. 32:5s:(suppl; abstr 5535).
-
(2014)
Journal of clinical oncology
, vol.32
, Issue.5
-
-
Lee, J.-M.1
Liu, J.2
Choyke, P.L.3
Elbuluk, O.4
Turkbey, I.B.5
Trepel, J.B.6
Lee, M.-J.7
Cao, L.8
Houston, N.D.9
Gordon, N.10
Figg, W.D.11
Barry, W.T.12
Matulonis, U.13
Birrer, M.J.14
Ivy, P.15
Kohn, E.C.16
-
28
-
-
51449113045
-
Targeted therapy for cancer using PARP inhibitors
-
Lord CJ, Ashworth A. Targeted therapy for cancer using PARP inhibitors. Current Opinion in Pharmacology 2008;8(4):363-9.
-
(2008)
Current Opinion in Pharmacology
, vol.8
, Issue.4
, pp. 363-369
-
-
Lord, C.J.1
Ashworth, A.2
-
29
-
-
84908449100
-
A randomized phase 2 trial comparing efficacy of the combination of the PARP inhibitor olaparib and the antiangiogenic cediranib against olaparib alone in recurrent platinum-sensitive ovarian cancer.
-
LBA550, 2014 ASCO Annual Meeting Abstracts
-
Liu J, Barry WT, Birrer MJ, Lee J-M, Buckanovich RJ, Fleming GF, Rimel B, Buss MK, Nattam SR, Hurteau J, Luo W, Quy P, Obermayer E, Whalen C, Lee H, Winer EP, Kohn EC, Ivy SP, Matulonis U. A randomized phase 2 trial comparing efficacy of the combination of the PARP inhibitor olaparib and the antiangiogenic cediranib against olaparib alone in recurrent platinum-sensitive ovarian cancer. Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts. 32(15_suppl); Vol. LBA550.
-
Journal of Clinical Oncology
, vol.32
, Issue.15
-
-
Liu, J.1
Barry, W.T.2
Birrer, M.J.3
Lee, J.-M.4
Buckanovich, R.J.5
Fleming, G.F.6
Rimel, B.7
Buss, M.K.8
Nattam, S.R.9
Hurteau, J.10
Luo, W.11
Quy, P.12
Obermayer, E.13
Whalen, C.14
Lee, H.15
Winer, E.P.16
Kohn, E.C.17
Ivy, S.P.18
Matulonis, U.19
-
30
-
-
84908134454
-
Combination cediranib and olaparib versus olaparib alone for women with recurrent platinum-sensitive ovarian cancer: a randomised phase 2 study
-
Liu JF, Barry WT, Birrer M, Lee JM, Buckanovich RJ, Fleming GF, Rimel B, Buss MK, Nattam S, Hurteau J, Luo W, Quy P, Whalen C, Obermayer L, Lee H, Winer EP, Kohn EC, Ivy SP, Matulonis UA. Combination cediranib and olaparib versus olaparib alone for women with recurrent platinum-sensitive ovarian cancer: a randomised phase 2 study. Lancet oncology 2014;15(11):1207-1214.
-
(2014)
Lancet oncology
, vol.15
, Issue.11
, pp. 1207-1214
-
-
Liu, J.F.1
Barry, W.T.2
Birrer, M.3
Lee, J.M.4
Buckanovich, R.J.5
Fleming, G.F.6
Rimel, B.7
Buss, M.K.8
Nattam, S.9
Hurteau, J.10
Luo, W.11
Quy, P.12
Whalen, C.13
Obermayer, L.14
Lee, H.15
Winer, E.P.16
Kohn, E.C.17
Ivy, S.P.18
Matulonis, U.A.19
-
31
-
-
85041549599
-
Food effect substudy of a phase 3 randomized double-blind trial of maintenance with niraparib (MK4827), a poly(ADP)ribose polymerase (PARP) inhibitor versus placebo in patients with platinum-sensitive ovarian cancer.
-
2014 ASCO Annual Meeting Abstracts. May
-
Moore KN, Zhang X-Y, Agarwal S, Patel MR, Burris HA, Martell RE, Kansra, V . Food effect substudy of a phase 3 randomized double-blind trial of maintenance with niraparib (MK4827), a poly(ADP)ribose polymerase (PARP) inhibitor versus placebo in patients with platinum-sensitive ovarian cancer. Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts. May 2014; Vol. 32(15_suppl):e16531.
-
(2014)
Journal of Clinical Oncology
, vol.32
, Issue.15
-
-
Moore, K.N.1
Zhang, X.-Y.2
Agarwal, S.3
Patel, M.R.4
Burris, H.A.5
Martell, R.E.6
Kansra, V.7
-
32
-
-
57649101120
-
Platinum compounds 30 years after the introduction of cisplatin: implications for the treatment of ovarian cancer
-
Muggia F. Platinum compounds 30 years after the introduction of cisplatin: implications for the treatment of ovarian cancer. Gynecologic Oncology 2009;112(1):275-81.
-
(2009)
Gynecologic Oncology
, vol.112
, Issue.1
, pp. 275-281
-
-
Muggia, F.1
-
33
-
-
84948716926
-
Preliminary results of ARIEL2, a phase 2 open-label study to identify ovarian cancer patients likely to respond to rucaparib
-
McNeish I, Coleman RL, Oza A, Konecny G, O'Malley DM, Kichenadasse G, et al. Preliminary results of ARIEL2, a phase 2 open-label study to identify ovarian cancer patients likely to respond to rucaparib. Annals of Oncology 2014;25(Suppl 4):iv305-26. [: clovistrials@emergingmed.com;: https://clinicaltrials.gov/ct2/show/NCT01891344]
-
(2014)
Annals of Oncology
, vol.25
, pp. iv305-iv326
-
-
McNeish, I.1
Coleman, R.L.2
Oza, A.3
Konecny, G.4
O'Malley, D.M.5
Kichenadasse, G.6
-
34
-
-
84884125515
-
Emerging treatment options for recurrent ovarian cancer: the potential role of olaparib
-
Shaw HM, Hall M. Emerging treatment options for recurrent ovarian cancer: the potential role of olaparib. OncoTargets and Therapy 2013;6:1197-206.
-
(2013)
OncoTargets and Therapy
, vol.6
, pp. 1197-1206
-
-
Shaw, H.M.1
Hall, M.2
-
36
-
-
34547187958
-
First in human phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of KU-0059436 (Ku), a small molecule inhibitor of poly ADP-ribose polymerase (PARP) in cancer patients (p), including BRCA1/2 mutation carriers
-
Yap TA, Boss DS, Fong PC. First in human phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of KU-0059436 (Ku), a small molecule inhibitor of poly ADP-ribose polymerase (PARP) in cancer patients (p), including BRCA1/2 mutation carriers. Journal of Clinical Oncology (Meeting Abstracts) 2007;25(18 Suppl):3529.
-
(2007)
Journal of Clinical Oncology (Meeting Abstracts)
, vol.25
, Issue.18
, pp. 3529
-
-
Yap, T.A.1
Boss, D.S.2
Fong, P.C.3
-
37
-
-
60749137451
-
Beyond chemotherapy: targeted therapies in ovarian cancer
-
Yap TA, Carden CP, Kaye SB. Beyond chemotherapy: targeted therapies in ovarian cancer. Nature Reviews Cancer 2009;9(3):167-81.
-
(2009)
Nature Reviews Cancer
, vol.9
, Issue.3
, pp. 167-181
-
-
Yap, T.A.1
Carden, C.P.2
Kaye, S.B.3
-
38
-
-
85041497631
-
A phase III, randomised, double blind, placebo controlled, multicentre study of olaparib maintenance monotherapy in patients with BRCA mutated advanced (FIGO stage III-IV) ovarian cancer following first line platinum based chemotherapy
-
DiSilvestro P, Moore K. A phase III, randomised, double blind, placebo controlled, multicentre study of olaparib maintenance monotherapy in patients with BRCA mutated advanced (FIGO stage III-IV) ovarian cancer following first line platinum based chemotherapy. https://clinicaltrials.gov/ct2/show/NCT01844986 2013.
-
(2013)
-
-
DiSilvestro, P.1
Moore, K.2
-
39
-
-
84906269444
-
SOLO1 and SOLO2: Randomized phase III trials of olaparib in patients (pts) with ovarian cancer and a BRCA1/2 mutation (BRCAm).
-
(Meeting Abstracts). May
-
Moore KN, DiSilvestro P, Lowe ES, Garnett S Pujade-Lauraine E. SOLO1 and SOLO2: Randomized phase III trials of olaparib in patients (pts) with ovarian cancer and a BRCA1/2 mutation (BRCAm). J Clin Oncol (Meeting Abstracts). May 2014; Vol. 32 (15-suppl):TPS5616.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Moore, K.N.1
DiSilvestro, P.2
Lowe, E.S.3
Garnett, S.P.-L.E.4
-
40
-
-
84902811306
-
A phase 3 randomized double-blind trial of maintenance with niraparib versus placebo in patients with platinum-sensitive ovarian cancer (ENGOT-OV16/NOVA trial).
-
Matulonis U, Mahner S, Wenham RM, Ledermann JA, Monk BJ, Del Campo JM, Berek JS, Vergote I, Fabbro M, Katsaros D, Marth C, Lorusso D, Herrstedt J, Agarwal S, RMartell RE, Mirza MR. A phase 3 randomized double-blind trial of maintenance with niraparib versus placebo in patients with platinum-sensitive ovarian cancer (ENGOT-OV16/NOVA trial). Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts. 32(15_sppl); Vol. TPS5625.
-
Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts
, vol.32
, Issue.15
-
-
Matulonis, U.1
Mahner, S.2
Wenham, R.M.3
Ledermann, J.A.4
Monk, B.J.5
Del Campo, J.M.6
Berek, J.S.7
Vergote, I.8
Fabbro, M.9
Katsaros, D.10
Marth, C.11
Lorusso, D.12
Herrstedt, J.13
Agarwal, S.14
RMartell, R.E.15
Mirza, M.R.16
-
41
-
-
85041543321
-
Engot-ov16/nova: A phase 3 randomized double-blind trial of maintenance with PARP-inhibitor niraparib versus placebo in patients with platinum-sensitive ovarian cancer
-
Conference: 15th Biennial Meeting of the International Gynecologic Cancer Society Melbourne, VIC Australia. Conference Start: 20141108 Conference End: 20141111. Conference Publication.
-
Mirza M, Berek JS, Vergote I, Wenham RM, Del Campo JM, Oza AM, Mahner S, Monk BJ, Fabbro M, Ledermann JA, Marth C, Bruchim I, Katsaros D, Lorusso D, Malander S, Dorum A, Agarwal S, Martell RE, Matulonis U. Engot-ov16/nova: A phase 3 randomized double-blind trial of maintenance with PARP-inhibitor niraparib versus placebo in patients with platinum-sensitive ovarian cancer. International journal of gynecological cancer 2014;Conference: 15th Biennial Meeting of the International Gynecologic Cancer Society Melbourne, VIC Australia. Conference Start: 20141108 Conference End: 20141111. Conference Publication. 2014:33-34.
-
(2014)
International journal of gynecological cancer 2014
, pp. 33-34
-
-
Mirza, M.1
Berek, J.S.2
Vergote, I.3
Wenham, R.M.4
Del Campo, J.M.5
Oza, A.M.6
Mahner, S.7
Monk, B.J.8
Fabbro, M.9
Ledermann, J.A.10
Marth, C.11
Bruchim, I.12
Katsaros, D.13
Lorusso, D.14
Malander, S.15
Dorum, A.16
Agarwal, S.17
Martell, R.E.18
Matulonis, U.19
-
42
-
-
85041537140
-
A maintenance study with niraparib versus placebo in patients with platinum sensitive ovarian cancer
-
Mirza MR, Matulonis U. A maintenance study with niraparib versus placebo in patients with platinum sensitive ovarian cancer. https://clinicaltrials.gov/ct2/show/NCT01847274 2013.
-
(2013)
-
-
Mirza, M.R.1
Matulonis, U.2
-
43
-
-
84906269444
-
SOLO1 and SOLO2: Randomized phase III trials of olaparib in patients (pts) with ovarian cancer and a BRCA1/2 mutation (BRCAm).
-
(May 20 Supplement), 2014
-
Moore KN, DiSilvestro P, Lowe ES, Garnett S Pujade-Lauraine E. SOLO1 and SOLO2: Randomized phase III trials of olaparib in patients (pts) with ovarian cancer and a BRCA1/2 mutation (BRCAm). Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts.Vol 32, No 15_suppl (May 20 Supplement), 2014: TPS5616. 2014.
-
(2014)
Journal of Clinical Oncology, 2014 ASCO Annual Meeting Abstracts
, vol.32
, Issue.15
-
-
Moore, K.N.1
DiSilvestro, P.2
Lowe, E.S.3
Garnett, S.P.-L.E.4
-
44
-
-
85041494570
-
Phase III randomised, double blind, placebo controlled study of olaparib maintenance monotherapy in platinum sensitive relapsed BRCA mutated ovarian cancer patients with a complete or partial response following platinum based chemotherapy
-
Pujade-Lauraine E. Phase III randomised, double blind, placebo controlled study of olaparib maintenance monotherapy in platinum sensitive relapsed BRCA mutated ovarian cancer patients with a complete or partial response following platinum based chemotherapy. https://clinicaltrials.gov/NCT01874353 2013.
-
(2013)
-
-
Pujade-Lauraine, E.1
-
45
-
-
85041547815
-
A study of rucaparib as switch maintenance following platinum-based chemotherapy in patients with platinum-sensitive, high-grade serous or endometrioid epithelial ovarian, primary peritoneal or fallopian tube cancer (ARIEL3)
-
6 April
-
A study of rucaparib as switch maintenance following platinum-based chemotherapy in patients with platinum-sensitive, high-grade serous or endometrioid epithelial ovarian, primary peritoneal or fallopian tube cancer (ARIEL3). ClinicalTrials.gov website 6 April 2015. [: https://clinicaltrials.gov/ct2/show/NCT01968213?term=NCT01968213&rank=1]
-
(2015)
ClinicalTrials.gov website
-
-
-
46
-
-
84929397322
-
ARIEL 2/3: An integrated clinical trial program to assess activity of rucaparib in ovarian cancer and to identify tumor molecular characteristics predictive of response.
-
(Meeting Abstracts). May
-
Swisher EM, McNeish IA, ColemanRL, Brenton J, Kaufmann SH, A Allen AR, Raponi M, Giordano H, Maloney L, JIsaacson J, aLedermann JA. ARIEL 2/3: An integrated clinical trial program to assess activity of rucaparib in ovarian cancer and to identify tumor molecular characteristics predictive of response. J Clin Oncol (Meeting Abstracts) vol. 32 no. 15_suppl TPS5619. May 2014; Vol. 32 (15_suppl):TPS5619.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Swisher, E.M.1
McNeish, I.A.2
Coleman, R.L.3
Brenton, J.4
Kaufmann, S.H.5
Allen, A.R.6
Raponi, M.7
Giordano, H.8
Maloney, L.9
JIsaacson, J.10
Ledermann, J.A.11
-
47
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 2005;434(7035):913-7.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
-
48
-
-
33645532464
-
Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair
-
Bryant HE, Helleday T. Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair. Nucleic Acids Research 2006;34(6):1685-91.
-
(2006)
Nucleic Acids Research
, vol.34
, Issue.6
, pp. 1685-1691
-
-
Bryant, H.E.1
Helleday, T.2
-
49
-
-
85041552183
-
Cancer Therapy Evaluation Program (CTEP), Common Terminology Criteria for Adverse Events, Version 4.03, DCTD, NCI, NIH, DHHS
-
May; updated June 2010, issue NIH Publication No. 09-5410
-
Cancer Therapy Evaluation Program (CTEP), Common Terminology Criteria for Adverse Events, Version 4.03, DCTD, NCI, NIH, DHHS. US Department of Health and Human Services (http://ctep.cancer.gov) May 2009; updated June 2010, issue NIH Publication No. 09-5410.
-
(2009)
US Department of Health and Human Services
-
-
-
51
-
-
0001910889
-
Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis
-
In: Egger M, Davey Smith G, Altman DG editor(s). 2nd Edition. London: BMJ Publication Group,
-
Deeks JJ, Altman DG, Bradburn MJ. Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. In: Egger M, Davey Smith G, Altman DG editor(s). Systematic Reviews in Health Care: Meta-Analysis in Context. 2nd Edition. London: BMJ Publication Group, 2001.
-
(2001)
Systematic Reviews in Health Care: Meta-Analysis in Context
-
-
Deeks, J.J.1
Altman, D.G.2
Bradburn, M.J.3
-
53
-
-
85041551237
-
Summary of opinion (initial authorisation): Lynparza (olaparib)
-
23 October
-
Committee for Medicinal Products for Human Use (CHMP). European Medicines Agency. Summary of opinion (initial authorisation): Lynparza (olaparib). European Medicines Agency, London 23 October 2014.
-
(2014)
European Medicines Agency, London
-
-
-
54
-
-
85051239045
-
Endnote X6
-
Letchworth,UK: Adept Scientific Ltd.,
-
Adept Scientific Ltd. Endnote X6. Letchworth, UK: Adept Scientific Ltd., 2012.
-
(2012)
-
-
-
56
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005;434(7035):917-21.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
-
57
-
-
84907850657
-
GLOBOCAN 2012v1.0, Cancer Incidence and Mortality Worldwide
-
[Internet]
-
Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, et al. GLOBOCAN 2012v1.0, Cancer Incidence and Mortality Worldwide. IARC CancerBase 2013, issue No. 11 [Internet].
-
(2013)
IARC CancerBase
, Issue.11
-
-
Ferlay, J.1
Soerjomataram, I.2
Ervik, M.3
Dikshit, R.4
Eser, S.5
Mathers, C.6
-
58
-
-
84945937474
-
GRADEpro[Computer program on www.gradepro.org].
-
Version [Jan 2015]. McMaster University,
-
McMaster University. GRADEpro[Computer program on www.gradepro.org]. Version [Jan 2015]. McMaster University, 2014.
-
(2014)
-
-
-
59
-
-
77955886707
-
Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer
-
Hennessy BT, Timms KM, Carey MS, Gutin A, Meyer LA, Flake DD 2nd, et al. Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer. Journal of Clinical Oncology 2010;28(22):3570-6.
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.22
, pp. 3570-3576
-
-
Hennessy, B.T.1
Timms, K.M.2
Carey, M.S.3
Gutin, A.4
Meyer, L.A.5
Flake, D.D.6
-
60
-
-
0041876133
-
Measuring inconsistency in meta-analyses
-
Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327(7414):557-60.
-
(2003)
BMJ
, vol.327
, Issue.7414
, pp. 557-560
-
-
Higgins, J.P.1
Thompson, S.G.2
Deeks, J.J.3
Altman, D.G.4
-
61
-
-
84887346660
-
Cochrane Handbook for Systematic Reviews of Interventions
-
Version 5.1.0 [updated March 2011]. The Cochrane Collaboration
-
Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
-
(2011)
-
-
Higgins, J.P.T.1
Green, S.2
-
62
-
-
18944390248
-
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
-
Jagtap P, Szabo C. Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. National Reviews of Drug Discovery 2005;4(5):421-40.
-
(2005)
National Reviews of Drug Discovery
, vol.4
, Issue.5
, pp. 421-440
-
-
Jagtap, P.1
Szabo, C.2
-
63
-
-
41349099104
-
Cancer statistics
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, et al. Cancer statistics. CA: A Cancer Journal for Clinicians 2008;58(2):71-96.
-
(2008)
CA: A Cancer Journal for Clinicians
, vol.58
, Issue.2
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
-
66
-
-
0032583387
-
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
-
Parmar MK, Torri V, Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Statistics in Medicine 1998;17(24):2815-34.
-
(1998)
Statistics in Medicine
, vol.17
, Issue.24
, pp. 2815-2834
-
-
Parmar, M.K.1
Torri, V.2
Stewart, L.3
-
67
-
-
51649091688
-
Poly(ADP-ribose)polymerase-1 (PARP-1) in carcinogenesis: potential role of PARP inhibitors in cancer treatment
-
Peralta-Leal A, Rodriguez MI, Oliver FJ. Poly(ADP-ribose)polymerase-1 (PARP-1) in carcinogenesis: potential role of PARP inhibitors in cancer treatment. Clinical Translations in Oncology 2008;10(6):318-23.
-
(2008)
Clinical Translations in Oncology
, vol.10
, Issue.6
, pp. 318-323
-
-
Peralta-Leal, A.1
Rodriguez, M.I.2
Oliver, F.J.3
-
69
-
-
33947380240
-
Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology
-
Ratnam K, Low JA. Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology. Clinical Cancer Research 2007;13(5):1383-8.
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.5
, pp. 1383-1388
-
-
Ratnam, K.1
Low, J.A.2
-
70
-
-
84891068902
-
The role of PARP inhibitors in the treatment of gynecologic malignancies
-
Reinbolt RE, Hays JL. The role of PARP inhibitors in the treatment of gynecologic malignancies. Frontiers in Oncology 2013;3(237):1-11.
-
(2013)
Frontiers in Oncology
, vol.3
, Issue.237
, pp. 1-11
-
-
Reinbolt, R.E.1
Hays, J.L.2
-
71
-
-
84964921069
-
Review Manager (RevMan)
-
5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration,
-
The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014.
-
(2014)
-
-
-
72
-
-
0035098503
-
Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer
-
Risch HA, McLaughlin JR, Cole DE, Rosen B, Bradley L, Kwan E, et al. Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. American Journal of Human Genetics 2001;68(3):700-10.
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.3
, pp. 700-710
-
-
Risch, H.A.1
McLaughlin, J.R.2
Cole, D.E.3
Rosen, B.4
Bradley, L.5
Kwan, E.6
-
74
-
-
84921430382
-
Chemotherapy for advanced ovarian cancer
-
Stewart L, Advanced Ovarian Cancer Trialists Group. Chemotherapy for advanced ovarian cancer. Cochrane Database of Systematic Reviews 1999, Issue 1. [DOI: 10.1002/14651858.CD001418]
-
(1999)
Cochrane Database of Systematic Reviews
, Issue.1
-
-
Stewart, L.1
-
76
-
-
58049114787
-
EORTC-GCG/NCIC-CTG Randomised trial comparing primary debulking surgery with neoadjuvant chemotherapy in stage IIIC-IV ovarian, fallopian tube and peritoneal cancer (OVCA)
-
Proceedings of the 12th Biennial Meeting of the International Gynecologic Cancer Society - IGCS. Bangkok,
-
Vergote I, Tropé CG, Amant F, Kristensen GB, Sardi JE, Ehlen T, et al. EORTC-GCG/NCIC-CTG Randomised trial comparing primary debulking surgery with neoadjuvant chemotherapy in stage IIIC-IV ovarian, fallopian tube and peritoneal cancer (OVCA). Proceedings of the 12th Biennial Meeting of the International Gynecologic Cancer Society - IGCS. Bangkok, 2008.
-
(2008)
-
-
Vergote, I.1
Tropé, C.G.2
Amant, F.3
Kristensen, G.B.4
Sardi, J.E.5
Ehlen, T.6
-
77
-
-
79960148154
-
Sorafenib enhances the anti-tumor effects of chemo-radiation treatment by down-regulating DNA repair proteins
-
Yadav A, Kumar B, Teknos TN, Kumar P. Sorafenib enhances the anti-tumor effects of chemo-radiation treatment by down-regulating DNA repair proteins. Molecular Cancer Therapeutics 2011;10:1241-51.
-
(2011)
Molecular Cancer Therapeutics
, vol.10
, pp. 1241-1251
-
-
Yadav, A.1
Kumar, B.2
Teknos, T.N.3
Kumar, P.4
-
79
-
-
70049104552
-
DNA-repair pathway inhibitors for the treatment of ovarian cancer
-
Martinek I, Haldar K, Gaitskell K, Nicum S, Kehoe S, Morrison J. DNA-repair pathway inhibitors for the treatment of ovarian cancer. Cochrane Database of Systematic Reviews 2009, Issue 4. [DOI: 10.1002/14651858.CD007929]
-
(2009)
Cochrane Database of Systematic Reviews
, Issue.4
-
-
Martinek, I.1
Haldar, K.2
Gaitskell, K.3
Nicum, S.4
Kehoe, S.5
Morrison, J.6
-
80
-
-
77954975816
-
DNA-repair pathway inhibitors for the treatment of ovarian cancer
-
Martinek I, Haldar K, Gaitskell K, Bryant A, Nicum S, Kehoe S, Morrison J. DNA-repair pathway inhibitors for the treatment of ovarian cancer. Cochrane Database of Systematic Reviews 2010, Issue 6. [DOI: 10.1002/14651858.CD007929.pub2]
-
(2010)
Cochrane Database of Systematic Reviews
, Issue.6
-
-
Martinek, I.1
Haldar, K.2
Gaitskell, K.3
Bryant, A.4
Nicum, S.5
Kehoe, S.6
Morrison, J.7
|