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Volumn 5, Issue 10, 2015, Pages

Common variants in the ARC gene are not associated with cognitive abilities

Author keywords

Activity regulated cytoskeleton associated protein; Cognition; Genetics; Memory; Single nucleotide polymorphism; Synaptic plasticity

Indexed keywords

ARC GENE; ARTICLE; BRAIN FUNCTION; COGNITION; GENE; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; MEMORY CONSOLIDATION; NERVE CELL PLASTICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; ADULT; AGED; ATTENTION DEFICIT DISORDER; COGNITIVE DEFECT; FEMALE; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; MALE; MIDDLE AGED; PHYSIOLOGY;

EID: 84945218154     PISSN: None     EISSN: 21623279     Source Type: Journal    
DOI: 10.1002/brb3.376     Document Type: Article
Times cited : (8)

References (57)
  • 1
    • 82555196668 scopus 로고    scopus 로고
    • Mutations causing syndromic autism define an axis of synaptic pathophysiology
    • Auerbach, B. D., E. K. Osterweil, and M. F. Bear . 2011. Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature 480:63-68.
    • (2011) Nature , vol.480 , pp. 63-68
    • Auerbach, B.D.1    Osterweil, E.K.2    Bear, M.F.3
  • 3
    • 33644644466 scopus 로고    scopus 로고
    • Identification and analysis of evolutionarily cohesive functional modules in protein networks
    • Campillos, M., C. von Mering, L. J. Jensen, and P. Bork . 2006. Identification and analysis of evolutionarily cohesive functional modules in protein networks. Genome Res. 16:374-382.
    • (2006) Genome Res. , vol.16 , pp. 374-382
    • Campillos, M.1    von Mering, C.2    Jensen, L.J.3    Bork, P.4
  • 4
    • 33750506086 scopus 로고    scopus 로고
    • Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking
    • Chowdhury, S., J. D. Shepherd, H. Okuno, G. Lyford, R. S. Petralia, N. Plath, et al. 2006. Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking. Neuron 52:445-459.
    • (2006) Neuron , vol.52 , pp. 445-459
    • Chowdhury, S.1    Shepherd, J.D.2    Okuno, H.3    Lyford, G.4    Petralia, R.S.5    Plath, N.6
  • 6
    • 80053132878 scopus 로고    scopus 로고
    • Genome-wide association studies establish that human intelligence is highly heritable and polygenic
    • Davies, G., A. Tenesa, A. Payton, J. Yang, S. Harris, D. Liewald, et al. 2011. Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Mol. Psychiatry 16:996-1005.
    • (2011) Mol. Psychiatry , vol.16 , pp. 996-1005
    • Davies, G.1    Tenesa, A.2    Payton, A.3    Yang, J.4    Harris, S.5    Liewald, D.6
  • 7
    • 84938550053 scopus 로고    scopus 로고
    • Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N = 53949)
    • Davies, G., N. Armstrong, J. C. Bis, J. Bressler, V. Chouraki, S. Giddaluru, et al. 2015. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N = 53949). Mol. Psychiatry 30:183-192.
    • (2015) Mol. Psychiatry , vol.30 , pp. 183-192
    • Davies, G.1    Armstrong, N.2    Bis, J.C.3    Bressler, J.4    Chouraki, V.5    Giddaluru, S.6
  • 13
    • 84872595085 scopus 로고    scopus 로고
    • Autism-related deficits via dysregulated eIF4E-dependent translational control
    • Gkogkas, C. G., A. Khoutorsky, I. Ran, E. Rampakakis, T. Nevarko, D. B. Weatherill, et al. 2013. Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature 493:371-377.
    • (2013) Nature , vol.493 , pp. 371-377
    • Gkogkas, C.G.1    Khoutorsky, A.2    Ran, I.3    Rampakakis, E.4    Nevarko, T.5    Weatherill, D.B.6
  • 14
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: etymology and strategic intentions
    • Gottesman, I., and T. Gould . 2003. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 160:636-645.
    • (2003) Am. J. Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.1    Gould, T.2
  • 15
    • 84863434758 scopus 로고    scopus 로고
    • Synaptopathies: diseases of the synaptome
    • Grant, S. G. N. 2012. Synaptopathies: diseases of the synaptome. Curr. Opin. Neurobiol. 22:522-529.
    • (2012) Curr. Opin. Neurobiol. , vol.22 , pp. 522-529
    • Grant, S.G.N.1
  • 16
    • 77649083119 scopus 로고    scopus 로고
    • The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc
    • Greer, P. L., R. Hanayama, B. L. Bloodgood, A. R. Mardinly, D. M. Lipton, S. W. Flavell, et al. 2010. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell 140:704-716.
    • (2010) Cell , vol.140 , pp. 704-716
    • Greer, P.L.1    Hanayama, R.2    Bloodgood, B.L.3    Mardinly, A.R.4    Lipton, D.M.5    Flavell, S.W.6
  • 17
    • 70349218127 scopus 로고    scopus 로고
    • Occupational outcome in adult ADHD: impact of symptom profile, comorbid psychiatric problems, and treatment: a cross-sectional study of 414 clinically diagnosed adult ADHD patients
    • Halmøy, A., O. B. Fasmer, C. Gillberg, and J. Haavik . 2009. Occupational outcome in adult ADHD: impact of symptom profile, comorbid psychiatric problems, and treatment: a cross-sectional study of 414 clinically diagnosed adult ADHD patients. J. Atten. Disord. 13:175-187.
    • (2009) J. Atten. Disord. , vol.13 , pp. 175-187
    • Halmøy, A.1    Fasmer, O.B.2    Gillberg, C.3    Haavik, J.4
  • 19
    • 84864417548 scopus 로고    scopus 로고
    • Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
    • Howie, B., C. Fuchsberger, M. Stephens, J. Marchini, and G. R. Abecasis . 2012. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat. Genet. 44:955-959.
    • (2012) Nat. Genet. , vol.44 , pp. 955-959
    • Howie, B.1    Fuchsberger, C.2    Stephens, M.3    Marchini, J.4    Abecasis, G.R.5
  • 21
    • 57349149630 scopus 로고    scopus 로고
    • Genetic analyses of dopamine related genes in adult ADHD patients suggest an association with the DRD5-microsatellite repeat, but not with DRD4 or SLC6A3 VNTRs
    • Johansson, S., H. Halleland, A. Halmøy, K. K. Jacobsen, E. T. Landaas, M. Dramsdahl, et al. 2008. Genetic analyses of dopamine related genes in adult ADHD patients suggest an association with the DRD5-microsatellite repeat, but not with DRD4 or SLC6A3 VNTRs. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B:1470-1475.
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.147B , pp. 1470-1475
    • Johansson, S.1    Halleland, H.2    Halmøy, A.3    Jacobsen, K.K.4    Landaas, E.T.5    Dramsdahl, M.6
  • 22
    • 84885210127 scopus 로고    scopus 로고
    • Schizophrenia is a cognitive illness: time for a change in focus
    • Kahn, R. S., and R. S. E. Keefe . 2013. Schizophrenia is a cognitive illness: time for a change in focus. JAMA Psychiatry 70:1107-1112.
    • (2013) JAMA Psychiatry , vol.70 , pp. 1107-1112
    • Kahn, R.S.1    Keefe, R.S.E.2
  • 23
    • 84856225986 scopus 로고    scopus 로고
    • De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
    • Kirov, G., A. J. Pocklington, P. Holmans, D. Ivanov, M. Ikeda, D. Ruderfer, et al. 2012. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol. Psychiatry 17:142-153.
    • (2012) Mol. Psychiatry , vol.17 , pp. 142-153
    • Kirov, G.1    Pocklington, A.J.2    Holmans, P.3    Ivanov, D.4    Ikeda, M.5    Ruderfer, D.6
  • 24
    • 82455205755 scopus 로고    scopus 로고
    • Arc in synaptic plasticity: from gene to behavior
    • Korb, E., and S. Finkbeiner . 2011. Arc in synaptic plasticity: from gene to behavior. Trends Neurosci. 34:591-598.
    • (2011) Trends Neurosci. , vol.34 , pp. 591-598
    • Korb, E.1    Finkbeiner, S.2
  • 25
    • 70449560421 scopus 로고    scopus 로고
    • Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities
    • Le Hellard, S., B. Håvik, T. Espeseth, H. Breilid, R. Løvlie, M. Luciano, et al. 2009. Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities. PLoS One 4:e7534.
    • (2009) PLoS One , vol.4
    • Le Hellard, S.1    Håvik, B.2    Espeseth, T.3    Breilid, H.4    Løvlie, R.5    Luciano, M.6
  • 26
    • 84862777863 scopus 로고    scopus 로고
    • Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
    • Lee, S. H., T. R. DeCandia, S. Ripke, J. Yang, P. F. Sullivan, M. E. Goddard, et al. 2012. Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nat. Genet. 44:247-250.
    • (2012) Nat. Genet. , vol.44 , pp. 247-250
    • Lee, S.H.1    DeCandia, T.R.2    Ripke, S.3    Yang, J.4    Sullivan, P.F.5    Goddard, M.E.6
  • 27
    • 84893661023 scopus 로고    scopus 로고
    • Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT)
    • Lencz, T., E. Knowles, G. Davies, S. Guha, D. C. Liewald, J. M. Starr, et al. 2014. Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT). Mol. Psychiatry 19:168-174.
    • (2014) Mol. Psychiatry , vol.19 , pp. 168-174
    • Lencz, T.1    Knowles, E.2    Davies, G.3    Guha, S.4    Liewald, D.C.5    Starr, J.M.6
  • 29
    • 78649508578 scopus 로고    scopus 로고
    • MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
    • Li, Y., C. J. Willer, J. Ding, P. Scheet, and G. R. Abecasis . 2010. MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet. Epidemiol. 34:816-834.
    • (2010) Genet. Epidemiol. , vol.34 , pp. 816-834
    • Li, Y.1    Willer, C.J.2    Ding, J.3    Scheet, P.4    Abecasis, G.R.5
  • 30
    • 58149464318 scopus 로고    scopus 로고
    • Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study
    • Lichtenstein, P., B. H. Yip, C. Björk, Y. Pawitan, T. D. Cannon, P. F. Sullivan, et al. 2009. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet 373:234-239.
    • (2009) Lancet , vol.373 , pp. 234-239
    • Lichtenstein, P.1    Yip, B.H.2    Björk, C.3    Pawitan, Y.4    Cannon, T.D.5    Sullivan, P.F.6
  • 31
    • 78349293844 scopus 로고    scopus 로고
    • The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood
    • Lichtenstein, P., E. Carlström, M. Råstam, C. Gillberg, and H. Anckarsäter . 2010. The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood. Am. J. Psychiatry 167:1357-1363.
    • (2010) Am. J. Psychiatry , vol.167 , pp. 1357-1363
    • Lichtenstein, P.1    Carlström, E.2    Råstam, M.3    Gillberg, C.4    Anckarsäter, H.5
  • 33
    • 84876936728 scopus 로고    scopus 로고
    • Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age
    • McIntosh, A. M., A. Gow, M. Luciano, G. Davies, D. C. Liewald, S. E. Harris, et al. 2013. Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age. Biol. Psychiatry 73:938-943.
    • (2013) Biol. Psychiatry , vol.73 , pp. 938-943
    • McIntosh, A.M.1    Gow, A.2    Luciano, M.3    Davies, G.4    Liewald, D.C.5    Harris, S.E.6
  • 34
    • 34848919232 scopus 로고    scopus 로고
    • Sustained Arc/Arg3.1 synthesis controls long-term potentiation consolidation through regulation of local actin polymerization in the dentate gyrus in vivo
    • Messaoudi, E., T. Kanhema, J. Soulé, A. Tiron, G. Dagyte, B. da Silva, et al. 2007. Sustained Arc/Arg3.1 synthesis controls long-term potentiation consolidation through regulation of local actin polymerization in the dentate gyrus in vivo. J. Neurosci. 27:10445-10455.
    • (2007) J. Neurosci. , vol.27 , pp. 10445-10455
    • Messaoudi, E.1    Kanhema, T.2    Soulé, J.3    Tiron, A.4    Dagyte, G.5    da Silva, B.6
  • 35
    • 84935027067 scopus 로고    scopus 로고
    • Arc is a flexible modular protein capable of reversible self-oligomerization
    • Myrum, C., A. Baumann, H. Bustad, M. Flydal, V. Mariaule, S. Alvira, et al. 2015. Arc is a flexible modular protein capable of reversible self-oligomerization. Biochem J. 468:145-158.
    • (2015) Biochem J. , vol.468 , pp. 145-158
    • Myrum, C.1    Baumann, A.2    Bustad, H.3    Flydal, M.4    Mariaule, V.5    Alvira, S.6
  • 39
    • 84912102497 scopus 로고    scopus 로고
    • Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK
    • Panja, D., J. W. Kenney, L. D'Andrea, F. Zalfa, A. Vedeler, K. Wibrand, et al. 2014. Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK. Cell Rep. 9:1430-1445.
    • (2014) Cell Rep. , vol.9 , pp. 1430-1445
    • Panja, D.1    Kenney, J.W.2    D'Andrea, L.3    Zalfa, F.4    Vedeler, A.5    Wibrand, K.6
  • 40
    • 0029996407 scopus 로고    scopus 로고
    • Executive functions and developmental psychopathology
    • Pennington, B. F., and S. Ozonoff . 1996. Executive functions and developmental psychopathology. J. Child Psychol. Psychiatry 37:51-87.
    • (1996) J. Child Psychol. Psychiatry , vol.37 , pp. 51-87
    • Pennington, B.F.1    Ozonoff, S.2
  • 41
    • 33750496896 scopus 로고    scopus 로고
    • Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories
    • Plath, N., O. Ohana, B. Dammermann, M. L. Errington, D. Schmitz, C. Gross, et al. 2006. Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron 52:437-444.
    • (2006) Neuron , vol.52 , pp. 437-444
    • Plath, N.1    Ohana, O.2    Dammermann, B.3    Errington, M.L.4    Schmitz, D.5    Gross, C.6
  • 44
    • 33750513623 scopus 로고    scopus 로고
    • Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission
    • Rial Verde, E. M., J. Lee-Osbourne, P. F. Worley, R. Malinow, and H. T. Cline . 2006. Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission. Neuron 52:461-474.
    • (2006) Neuron , vol.52 , pp. 461-474
    • Rial Verde, E.M.1    Lee-Osbourne, J.2    Worley, P.F.3    Malinow, R.4    Cline, H.T.5
  • 45
    • 84885020424 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies 13 new risk loci for schizophrenia
    • Ripke, S., C. O'Dushlaine, K. Chambert, J. L. Moran, A. K. Kähler, S. Akterin, et al. 2013. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat. Genet. 45:1150-1159.
    • (2013) Nat. Genet. , vol.45 , pp. 1150-1159
    • Ripke, S.1    O'Dushlaine, C.2    Chambert, K.3    Moran, J.L.4    Kähler, A.K.5    Akterin, S.6
  • 46
  • 47
    • 79952006979 scopus 로고    scopus 로고
    • New views of Arc, a master regulator of synaptic plasticity
    • Shepherd, J. D., and M. F. Bear . 2011. New views of Arc, a master regulator of synaptic plasticity. Nat. Neurosci. 14:279-284.
    • (2011) Nat. Neurosci. , vol.14 , pp. 279-284
    • Shepherd, J.D.1    Bear, M.F.2
  • 48
    • 33750503402 scopus 로고    scopus 로고
    • Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors
    • Shepherd, J. D., G. Rumbaugh, J. Wu, S. Chowdhury, N. Plath, D. Kuhl, et al. 2006. Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors. Neuron 52:475-484.
    • (2006) Neuron , vol.52 , pp. 475-484
    • Shepherd, J.D.1    Rumbaugh, G.2    Wu, J.3    Chowdhury, S.4    Plath, N.5    Kuhl, D.6
  • 49
    • 84860351742 scopus 로고    scopus 로고
    • Identification of common variants associated with human hippocampal and intracranial volumes
    • Stein, J. L., S. E. Medland, A. A. Vasquez, D. P. Hibar, R. E. Senstad, A. M. Winkler, et al. 2012. Identification of common variants associated with human hippocampal and intracranial volumes. Nat. Genet. 44:552-561.
    • (2012) Nat. Genet. , vol.44 , pp. 552-561
    • Stein, J.L.1    Medland, S.E.2    Vasquez, A.A.3    Hibar, D.P.4    Senstad, R.E.5    Winkler, A.M.6
  • 50
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: the emerging picture and its implications
    • Sullivan, P. F., M. J. Daly, and M. O'Donovan . 2012. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat. Rev. Genet. 13:537-551.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3
  • 51
    • 84923077204 scopus 로고    scopus 로고
    • Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
    • The Netwok and Pathway Analysis Subgroup of the Psyciatric Genomics Consortium. 2015. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat. Neurosci. 18:199-209.
    • (2015) Nat. Neurosci. , vol.18 , pp. 199-209
  • 52
    • 77955093058 scopus 로고    scopus 로고
    • Key role for gene dosage and synaptic homeostasis in autism spectrum disorders
    • Toro, R., M. Konyukh, R. Delorme, C. Leblond, P. Chaste, F. Fauchereau, et al. 2010. Key role for gene dosage and synaptic homeostasis in autism spectrum disorders. Trends Genet. 26:363-372.
    • (2010) Trends Genet. , vol.26 , pp. 363-372
    • Toro, R.1    Konyukh, M.2    Delorme, R.3    Leblond, C.4    Chaste, P.5    Fauchereau, F.6
  • 53
    • 33746955145 scopus 로고    scopus 로고
    • Spatial exploration induces ARC, a plasticity-related immediate-early gene, only in calcium/calmodulin-dependent protein kinase II-positive principal excitatory and inhibitory neurons of the rat forebrain
    • Vazdarjanova, A., V. Ramirez-Amaya, N. Insel, T. K. Plummer, S. Rosi, S. Chowdhury, et al. 2006. Spatial exploration induces ARC, a plasticity-related immediate-early gene, only in calcium/calmodulin-dependent protein kinase II-positive principal excitatory and inhibitory neurons of the rat forebrain. J. Comp. Neurol. 498:317-329.
    • (2006) J. Comp. Neurol. , vol.498 , pp. 317-329
    • Vazdarjanova, A.1    Ramirez-Amaya, V.2    Insel, N.3    Plummer, T.K.4    Rosi, S.5    Chowdhury, S.6
  • 54
    • 84860151961 scopus 로고    scopus 로고
    • Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses
    • Visscher, P. M., M. E. Goddard, E. M. Derks, and N. R. Wray . 2012. Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses. Mol. Psychiatry 17:474-485.
    • (2012) Mol. Psychiatry , vol.17 , pp. 474-485
    • Visscher, P.M.1    Goddard, M.E.2    Derks, E.M.3    Wray, N.R.4
  • 56
    • 80155123814 scopus 로고    scopus 로고
    • Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation
    • Wu, J., R. S. Petralia, H. Kurushima, H. Patel, M. Jung, L. Volk, et al. 2011. Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation. Cell 147:615-628.
    • (2011) Cell , vol.147 , pp. 615-628
    • Wu, J.1    Petralia, R.S.2    Kurushima, H.3    Patel, H.4    Jung, M.5    Volk, L.6
  • 57
    • 84929163928 scopus 로고    scopus 로고
    • Structural Basis of Arc Binding to Synaptic Proteins: implications for Cognitive Disease
    • Zhang, W., J. Wu, M. D. Ward, S. Yang, Y.-A. Chuang, M. Xiao, et al. 2015. Structural Basis of Arc Binding to Synaptic Proteins: implications for Cognitive Disease. Neuron 86:490-500.
    • (2015) Neuron , vol.86 , pp. 490-500
    • Zhang, W.1    Wu, J.2    Ward, M.D.3    Yang, S.4    Chuang, Y.-A.5    Xiao, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.