Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses

Molecular Psychiatry

Volumn 17, Issue 5, 2012, Pages 474-485

  Visscher, P M ^a   Goddard, M E ^b,c   Derks, E M ^d   Wray, N R ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b DEPARTMENT OF PRIMARY INDUSTRIES   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

bipolar disorder; genetic architecture; GWAS; heritability; major depression; schizophrenia

Indexed keywords

BIPOLAR DISORDER; BREAST CANCER; CARDIOVASCULAR DISEASE; CHROMOSOME STRUCTURE; DIABETES MELLITUS; EPISTASIS; EVIDENCE BASED PRACTICE; EXOME; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HERITABILITY; HUMAN; MAJOR DEPRESSION; MENTAL DISEASE; MOLECULAR EVOLUTION; MONOZYGOTIC TWINS; PHENYLKETONURIA; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA; SICKLE CELL ANEMIA; SINGLE NUCLEOTIDE POLYMORPHISM;

GENETIC PREDISPOSITION TO DISEASE; HUMANS; MENTAL DISORDERS; MULTIFACTORIAL INHERITANCE; POLYMORPHISM, GENETIC;

EID: 84860151961     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2011.65     Document Type: Review

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