메뉴 건너뛰기




Volumn 19, Issue 2, 2014, Pages 168-174

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: A report from the Cognitive Genomics consorTium (COGENT)

(46)  Lencz, T a,b,c   Knowles, E d   Davies, G e   Guha, S a   Liewald, D C e   Starr, J M e   Djurovic, S f,g   Melle, I f,g,h   Sundet, K f,h   Christoforou, A i,j   Reinvang, I h   Mukherjee, S a,b   Derosse, Pamela a,b   Lundervold, A i,k   Steen, V M i,j   John, M a,b   Espeseth, T g,h   Raikkonen K l,m   Widen, E l   Palotie, A l,n   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; ENDOPHENOTYPE; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENERAL COGNITIVE ABILITY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HUMAN; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MIDDLE AGED; MOLECULAR GENETICS; PRIORITY JOURNAL; RISK ASSESSMENT; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

EID: 84893661023     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2013.166     Document Type: Article
Times cited : (161)

References (53)
  • 1
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003; 160: 636-645.
    • (2003) Am J Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 3
    • 84860760353 scopus 로고    scopus 로고
    • A population-based study of shared genetic variation between premorbid IQ and psychosis among male twin pairs and sibling pairs from Sweden
    • Fowler T, Zammit S, Owen MJ, Rasmussen F. A population-based study of shared genetic variation between premorbid IQ and psychosis among male twin pairs and sibling pairs from Sweden. Arch Gen Psychiatry 2012; 69: 460-466.
    • (2012) Arch Gen Psychiatry , vol.69 , pp. 460-466
    • Fowler, T.1    Zammit, S.2    Owen, M.J.3    Rasmussen, F.4
  • 4
    • 84866740487 scopus 로고    scopus 로고
    • The role of phenotype in gene discovery in the whole genome sequencing era
    • Almasy L. The role of phenotype in gene discovery in the whole genome sequencing era. Hum Genet 2012; 131: 1533-1540.
    • (2012) Hum Genet , vol.131 , pp. 1533-1540
    • Almasy, L.1
  • 5
    • 80051918472 scopus 로고    scopus 로고
    • The genetics of cognitive impairment in schizophrenia: A phenomic perspective
    • Bilder RM, Howe A, Novak N, Sabb FW, Parker DS. The genetics of cognitive impairment in schizophrenia: a phenomic perspective. Trends Cogn Sci 2011; 15: 428-435.
    • (2011) Trends Cogn Sci , vol.15 , pp. 428-435
    • Bilder, R.M.1    Howe, A.2    Novak, N.3    Sabb, F.W.4    Parker, D.S.5
  • 6
    • 84862777863 scopus 로고    scopus 로고
    • Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ), International Schizophrenia Consortium (ISC). Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
    • Lee SH, DeCandia TR, Ripke S, Yang J, Sullivan PF, Goddard ME et al. Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ), International Schizophrenia Consortium (ISC). Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs. Nat Genet 2012; 44: 247-250.
    • (2012) Nat Genet , vol.44 , pp. 247-250
    • Lee, S.H.1    Decandia, T.R.2    Ripke, S.3    Yang, J.4    Sullivan, P.F.5    Goddard, M.E.6
  • 7
    • 80053132878 scopus 로고    scopus 로고
    • Genome-wide association studies establish that human intelligence is highly heritable and polygenic
    • Davies G, Tenesa A, Payton A, Yang J, Harris SE, Liewald D et al. Genome-wide association studies establish that human intelligence is highly heritable and polygenic. Mol Psychiatry 2011; 16: 996-1005.
    • (2011) Mol Psychiatry , vol.16 , pp. 996-1005
    • Davies, G.1    Tenesa, A.2    Payton, A.3    Yang, J.4    Harris, S.E.5    Liewald, D.6
  • 8
    • 84876196443 scopus 로고    scopus 로고
    • Wellcome Trust Case Control Consortium 2 Common DNA markers can account for more than half of the genetic influence on cognitive abilities
    • Plomin R, Haworth CM, Meaburn EL, Price TS, Davis OS. Wellcome Trust Case Control Consortium 2 Common DNA markers can account for more than half of the genetic influence on cognitive abilities. Psychol Sci 2013; 24: 562-568.
    • (2013) Psychol Sci , vol.24 , pp. 562-568
    • Plomin, R.1    Haworth, C.M.2    Meaburn, E.L.3    Price, T.S.4    Davis, O.S.5
  • 10
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium.
    • International Schizophrenia Consortium. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009; 460: 748-752.
    • (2009) Nature , vol.460 , pp. 748-752
  • 11
    • 84876936728 scopus 로고    scopus 로고
    • Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age
    • McIntosh AM, Gow A, Luciano M, Davies G, Liewald DC, Harris SE et al. Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age. Biol Psychiatry 2013; 73: 938-943.
    • (2013) Biol Psychiatry , vol.73 , pp. 938-943
    • McIntosh, A.M.1    Gow, A.2    Luciano, M.3    Davies, G.4    Liewald, D.C.5    Harris, S.E.6
  • 13
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium.
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Genome-wide association study identifies five new schizophrenia loci. Nat Genet 2011; 43: 969-976.
    • (2011) Nat Genet , vol.43 , pp. 969-976
  • 14
    • 84883313538 scopus 로고    scopus 로고
    • Neurocognitive phenomics: Examining the genetic basis of cognitive abilities
    • Donohoe G, Deary IJ, Glahn DC, Malhotra AK, Burdick KE. Neurocognitive phenomics: examining the genetic basis of cognitive abilities. Psychol Med 2012; 43: 2027-2036.
    • (2012) Psychol Med , vol.43 , pp. 2027-2036
    • Donohoe, G.1    Deary, I.J.2    Glahn, D.C.3    Malhotra, A.K.4    Burdick, K.E.5
  • 15
    • 53249084473 scopus 로고    scopus 로고
    • General and specific cognitive deficits in schizophrenia: Goliath defeats David?
    • Dickinson D, Ragland JD, Gold JM, Gur RC. General and specific cognitive deficits in schizophrenia: Goliath defeats David? Biol Psychiatry 2008; 64: 823-827.
    • (2008) Biol Psychiatry , vol.64 , pp. 823-827
    • Dickinson, D.1    Ragland, J.D.2    Gold, J.M.3    Gur, R.C.4
  • 16
    • 84868328942 scopus 로고    scopus 로고
    • Cognitive impairment in schizophrenia
    • Keefe RS, Harvey PD. Cognitive impairment in schizophrenia. Handb Exp Pharmacol 2012; 213: 11-37.
    • (2012) Handb Exp Pharmacol , vol.213 , pp. 11-37
    • Keefe, R.S.1    Harvey, P.D.2
  • 18
    • 77249137659 scopus 로고    scopus 로고
    • The neuroscience of human intelligence differences
    • Deary IJ, Penke L, Johnson W. The neuroscience of human intelligence differences. Nat Rev Neurosci 2010; 11: 201-211.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 201-211
    • Deary, I.J.1    Penke, L.2    Johnson, W.3
  • 19
    • 67651095887 scopus 로고    scopus 로고
    • Genetic foundations of human intelligence
    • Deary IJ, Johnson W, Houlihan LM. Genetic foundations of human intelligence. Hum Genet 2009; 126: 215-232.
    • (2009) Hum Genet , vol.126 , pp. 215-232
    • Deary, I.J.1    Johnson, W.2    Houlihan, L.M.3
  • 20
    • 0035260431 scopus 로고    scopus 로고
    • The genetics of g in human and mouse
    • Plomin R. The genetics of g in human and mouse. Nat Rev Neurosci 2001; 2: 136-141.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 136-141
    • Plomin, R.1
  • 23
    • 37349132395 scopus 로고    scopus 로고
    • Still just 1 g: Consistent results from five test batteries
    • Johnson W, Nijenhuis JT, Bouchard TJ. Jr. Still just 1 g: consistent results from five test batteries. Intelligence 2008; 36: 81-95.
    • (2008) Intelligence , vol.36 , pp. 81-95
    • Johnson, W.1    Nijenhuis, J.T.2    Bouchard, Jr.T.J.3
  • 24
    • 43349097737 scopus 로고    scopus 로고
    • No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: Implications for psychiatric genetics
    • Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C et al. No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. Am J Psychiatry 2008; 165: 497-506.
    • (2008) Am J Psychiatry , vol.165 , pp. 497-506
    • Sanders, A.R.1    Duan, J.2    Levinson, D.F.3    Shi, J.4    He, D.5    Hou, C.6
  • 25
    • 68449096727 scopus 로고    scopus 로고
    • Common variants on chromosome 6p22.1 are associated with schizophrenia
    • Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe'er I et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 2009; 460: 753-757.
    • (2009) Nature , vol.460 , pp. 753-757
    • Shi, J.1    Levinson, D.F.2    Duan, J.3    Sanders, A.R.4    Zheng, Y.5    Pe'Er, I.6
  • 26
    • 79952710338 scopus 로고    scopus 로고
    • Copy number variants in schizophrenia: Confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications
    • Levinson DF, Duan J, Oh S, Wang K, Sanders AR, Shi J et al. Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. Am J Psychiatry 2011; 168: 302-316.
    • (2011) Am J Psychiatry , vol.168 , pp. 302-316
    • Levinson, D.F.1    Duan, J.2    Oh, S.3    Wang, K.4    Sanders, A.R.5    Shi, J.6
  • 29
  • 30
    • 84883778249 scopus 로고    scopus 로고
    • Additive genetic variation in schizophrenia risk is shared by populations of african and European descent
    • de Candia TR, Lee SH, Yang J, Browning BL, Gejman PV, Levinson DF et al. Additive genetic variation in schizophrenia risk is shared by populations of african and European descent. Am J Hum Genet 2013; 93: 463-470.
    • (2013) Am J Hum Genet , vol.93 , pp. 463-470
    • De Candia, T.R.1    Lee, S.H.2    Yang, J.3    Browning, B.L.4    Gejman, P.V.5    Levinson, D.F.6
  • 31
    • 80055080761 scopus 로고    scopus 로고
    • Identification, replication, and fine-mapping of loci associated with adult height in individuals of african ancestry
    • N'Diaye A, Chen GK, Palmer CD, Ge B, Tayo B, Mathias RA et al. Identification, replication, and fine-mapping of loci associated with adult height in individuals of african ancestry. PLoS Genet 2011; 7: e1002298.
    • (2011) PLoS Genet , vol.7
    • N'Diaye, A.1    Chen, G.K.2    Palmer, C.D.3    Ge, B.4    Tayo, B.5    Mathias, R.A.6
  • 32
  • 33
    • 84856478855 scopus 로고    scopus 로고
    • A linear complexity phasing method for thousands of genomes
    • Delaneau O, Marchini J, Zagury JF. A linear complexity phasing method for thousands of genomes. Nat Methods 2011; 9: 179-181.
    • (2011) Nat Methods , vol.9 , pp. 179-181
    • Delaneau, O.1    Marchini, J.2    Zagury, J.F.3
  • 35
    • 84864417548 scopus 로고    scopus 로고
    • Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
    • Howie B, Fuchsberger C, Stephens M, Marchini J, Abecasis GR. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat Genet 2012; 44: 955-959.
    • (2012) Nat Genet , vol.44 , pp. 955-959
    • Howie, B.1    Fuchsberger, C.2    Stephens, M.3    Marchini, J.4    Abecasis, G.R.5
  • 37
    • 0000600340 scopus 로고
    • General intelligence objectively determined and measured
    • Spearman C. General intelligence objectively determined and measured. Am J Psychology 1904; 15: 201-293.
    • (1904) Am J Psychology , vol.15 , pp. 201-293
    • Spearman, C.1
  • 40
    • 0031278215 scopus 로고    scopus 로고
    • Meta-analyses of age-cognition relations in adulthood: Estimates of linear and nonlinear age effects and structural models
    • Verhaeghen P, Salthouse TA. Meta-analyses of age-cognition relations in adulthood: estimates of linear and nonlinear age effects and structural models. Psychol Bull 1997; 122: 231-249.
    • (1997) Psychol Bull , vol.122 , pp. 231-249
    • Verhaeghen, P.1    Salthouse, T.A.2
  • 44
    • 77957947562 scopus 로고    scopus 로고
    • Hundreds of variants clustered in genomic loci and biological pathways affect human height
    • Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010; 467: 832-838.
    • (2010) Nature , vol.467 , pp. 832-838
    • Lango Allen, H.1    Estrada, K.2    Lettre, G.3    Berndt, S.I.4    Weedon, M.N.5    Rivadeneira, F.6
  • 45
    • 84856100262 scopus 로고    scopus 로고
    • Mouse models of genetic effects on cognition: Relevance to schizophrenia
    • Papaleo F, Lipska BK, Weinberger DR. Mouse models of genetic effects on cognition: relevance to schizophrenia. Neuropharmacology 2012; 62: 1204-1220.
    • (2012) Neuropharmacology , vol.62 , pp. 1204-1220
    • Papaleo, F.1    Lipska, B.K.2    Weinberger, D.R.3
  • 46
    • 78951489167 scopus 로고    scopus 로고
    • A neuropsychological investigation of the genome wide associated schizophrenia risk variant NRGN rs12807809
    • Donohoe G, Walters J, Morris DW, Da Costa A, Rose E, Hargreaves A et al. A neuropsychological investigation of the genome wide associated schizophrenia risk variant NRGN rs12807809. Schizophr Res 2011; 125: 304-306.
    • (2011) Schizophr Res , vol.125 , pp. 304-306
    • Donohoe, G.1    Walters, J.2    Morris, D.W.3    Da Costa, A.4    Rose, E.5    Hargreaves, A.6
  • 47
    • 84871838046 scopus 로고    scopus 로고
    • The effect of neurogranin on neural correlates of episodic memory encoding and retrieval
    • Krug A, Krach S, Jansen A, Nieratschker V, Witt SH, Shah NJ et al. The effect of neurogranin on neural correlates of episodic memory encoding and retrieval. Schizophr Bull 2013; 39: 141-150.
    • (2013) Schizophr Bull , vol.39 , pp. 141-150
    • Krug, A.1    Krach, S.2    Jansen, A.3    Nieratschker, V.4    Witt, S.H.5    Shah, N.J.6
  • 48
    • 84855820198 scopus 로고    scopus 로고
    • Impact of the genome wide supported NRGN gene on anterior cingulate morphology in schizophrenia
    • Ohi K, Hashimoto R, Yasuda Y, Nemoto K, Ohnishi T, Fukumoto M et al. Impact of the genome wide supported NRGN gene on anterior cingulate morphology in schizophrenia. PLoS ONE 2012; 7: e29780.
    • (2012) PLoS ONE , vol.7
    • Ohi, K.1    Hashimoto, R.2    Yasuda, Y.3    Nemoto, K.4    Ohnishi, T.5    Fukumoto, M.6
  • 49
    • 84871389804 scopus 로고    scopus 로고
    • The effect of the neurogranin schizophrenia risk variant rs12807809 on brain structure and function
    • Rose EJ, Morris DW, Fahey C, Robertson IH, Greene C, O'Doherty J et al. The effect of the neurogranin schizophrenia risk variant rs12807809 on brain structure and function. Twin Res Hum Genet 2012; 15: 296-303.
    • (2012) Twin Res Hum Genet , vol.15 , pp. 296-303
    • Rose, E.J.1    Morris, D.W.2    Fahey, C.3    Robertson, I.H.4    Greene, C.5    O'Doherty, J.6
  • 50
    • 80054867944 scopus 로고    scopus 로고
    • Risk variant for schizophrenia in the neurogranin gene impacts on hippocampus activation during contextual fear conditioning
    • Pohlack ST, Nees F, Ruttorf M, Witt SH, Nieratschker V, Rietschel M, Flor H. Risk variant for schizophrenia in the neurogranin gene impacts on hippocampus activation during contextual fear conditioning. Mol Psychiatry 2011; 16: 1072-1073.
    • (2011) Mol Psychiatry , vol.16 , pp. 1072-1073
    • Pohlack, S.T.1    Nees, F.2    Ruttorf, M.3    Witt, S.H.4    Nieratschker, V.5    Rietschel, M.6    Flor, H.7
  • 51
    • 84873701087 scopus 로고    scopus 로고
    • Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
    • Andreassen OA, Djurovic S, Thompson WK, Schork AJ, Kendler KS, O'Donovan MC et al. Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. Am J Hum Genet 2013; 92: 197-209.
    • (2013) Am J Hum Genet , vol.92 , pp. 197-209
    • Andreassen, O.A.1    Djurovic, S.2    Thompson, W.K.3    Schork, A.J.4    Kendler, K.S.5    O'Donovan, M.C.6
  • 52
    • 34748830310 scopus 로고    scopus 로고
    • A common variant of HMGA2 is associated with adult and childhood height in the general population
    • Weedon MN, Lettre G, Freathy RM, Lindgren CM, Voight BF, Perry JR et al. A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet 2007; 39: 1245-1245.
    • (2007) Nat Genet , vol.39 , pp. 1245-1245
    • Weedon, M.N.1    Lettre, G.2    Freathy, R.M.3    Lindgren, C.M.4    Voight, B.F.5    Perry, J.R.6
  • 53
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3    Zeggini, E.4    Freathy, R.M.5    Lindgren, C.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.