Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway

Journal of Neurochemistry

Volumn 135, Issue 3, 2015, Pages 630-637

  Deng, Juan ^a,b   Habib, Ahsan ^a   Obregon, Demian F ^a   Barger, Steven W ^c   Giunta, Brian ^a   Wang, Yan Jiang ^b   Hou, Huayan ^a   Sawmiller, Darrell ^a   Tan, Jun ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Alzheimer's disease; BACE1; GSK3 ; sAPP ; tau

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN ALPHA; BETA SECRETASE 1; GAMMA SECRETASE; GLYCOGEN SYNTHASE KINASE 3BETA; RECOMBINANT PROTEIN; TAU PROTEIN; UNCLASSIFIED DRUG; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, HUMAN; GSK3B PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; GENE OVEREXPRESSION; HELA CELL LINE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TUMOR CELL LINE;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HUMANS; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TAU PROTEINS;

EID: 84945186786     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13351     Document Type: Article

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