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Volumn 21, Issue 8, 2015, Pages 802-812

Gene expression analysis in human polymorphonuclear leukocytes stimulated by LPSs from nosocomial opportunistic pathogens

Author keywords

LPS; MDRA; MDRP; polymorphonuclear leukocyte; RT PCR

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8 RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TUMOR NECROSIS FACTOR ALPHA; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE, ESCHERICHIA COLI O111 B4; TLR4 PROTEIN, HUMAN;

EID: 84945178441     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425915605892     Document Type: Article
Times cited : (13)

References (49)
  • 1
    • 35348856289 scopus 로고    scopus 로고
    • Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells
    • Gioannini TL, Weiss JP,. Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells. Immunol Res 2007; 39: 249-260.
    • (2007) Immunol Res , vol.39 , pp. 249-260
    • Gioannini, T.L.1    Weiss, J.P.2
  • 2
    • 66949122854 scopus 로고    scopus 로고
    • Approaching the asymptote: 20 years later
    • Medzhitov R,. Approaching the asymptote: 20 years later. Immunity 2009; 30: 766-775.
    • (2009) Immunity , vol.30 , pp. 766-775
    • Medzhitov, R.1
  • 3
    • 77749309281 scopus 로고    scopus 로고
    • Virulence and immunomodulatory roles of bacterial outer membrane vesicles
    • Ellis TN, Kuehn MJ,. Virulence and immunomodulatory roles of bacterial outer membrane vesicles. Microbiol Mol Biol R 2010; 74: 81-94.
    • (2010) Microbiol Mol Biol R , vol.74 , pp. 81-94
    • Ellis, T.N.1    Kuehn, M.J.2
  • 4
    • 0033584935 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa
    • Ernest RK, Yi EC, Guo L, et al. Pseudomonas aeruginosa. Science 1999; 286: 1561-1565.
    • (1999) Science , vol.286 , pp. 1561-1565
    • Ernest, R.K.1    Yi, E.C.2    Guo, L.3
  • 5
    • 0142074779 scopus 로고    scopus 로고
    • Alterations in the formation of lipopolysaccharide and membrane vesicles on the surface of Pseudomonas aeruginosa PAO1 under oxygen stress conditions
    • Sabra W, Lundsdorf H, Zeng AP,. Alterations in the formation of lipopolysaccharide and membrane vesicles on the surface of Pseudomonas aeruginosa PAO1 under oxygen stress conditions. Microbiology 2003; 149: 2789-2795.
    • (2003) Microbiology , vol.149 , pp. 2789-2795
    • Sabra, W.1    Lundsdorf, H.2    Zeng, A.P.3
  • 6
    • 84945222166 scopus 로고    scopus 로고
    • (last accessed 1 July 2015)
    • http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/Guidances/default.htm (last accessed 1 July 2015).
  • 7
    • 0001244786 scopus 로고
    • Isolation of lipopolysaccharides from bacteria
    • Leive L, Morrison DC,. Isolation of lipopolysaccharides from bacteria. Methods Enzymol 1972; 28: 254-262.
    • (1972) Methods Enzymol , vol.28 , pp. 254-262
    • Leive, L.1    Morrison, D.C.2
  • 8
    • 41949106115 scopus 로고    scopus 로고
    • Influences of aflatoxin B1 in reactive oxygen species generation and chemotaxis of human polymorphonuclear leukocytes
    • Ubagai T, Tansho S, Ito T, et al. Influences of aflatoxin B1 in reactive oxygen species generation and chemotaxis of human polymorphonuclear leukocytes. Toxicol in Vitro 2008; 22: 1115-1120.
    • (2008) Toxicol in Vitro , vol.22 , pp. 1115-1120
    • Ubagai, T.1    Tansho, S.2    Ito, T.3
  • 9
    • 76749141388 scopus 로고    scopus 로고
    • Downregulation of immunomdulator gene expression in LPS-stimulated human polymorphonuclear leukocytes by the proton pump inhibitor lansoprazole
    • Ubagai T, Koshibu Y, Koshio O, et al. Downregulation of immunomdulator gene expression in LPS-stimulated human polymorphonuclear leukocytes by the proton pump inhibitor lansoprazole. J Infect Chemother 2009; 15: 374-379.
    • (2009) J Infect Chemother , vol.15 , pp. 374-379
    • Ubagai, T.1    Koshibu, Y.2    Koshio, O.3
  • 10
    • 84892164853 scopus 로고    scopus 로고
    • Gene expression analysis of TREM1 and GRK2 in polymorphonuclear leukocytes as the surrogate biomarkers of acute bacterial infections
    • Ubagai T, Nakano R, Kikuchi H, et al. Gene expression analysis of TREM1 and GRK2 in polymorphonuclear leukocytes as the surrogate biomarkers of acute bacterial infections. Int J Med Sci 2014; 11: 215-221.
    • (2014) Int J Med Sci , vol.11 , pp. 215-221
    • Ubagai, T.1    Nakano, R.2    Kikuchi, H.3
  • 11
    • 2342525996 scopus 로고    scopus 로고
    • Regulation of phagosome maturation by signals from Toll-like receptors
    • Blander JM, Medzhitov R,. Regulation of phagosome maturation by signals from Toll-like receptors. Science 2004; 304: 1014-1018.
    • (2004) Science , vol.304 , pp. 1014-1018
    • Blander, J.M.1    Medzhitov, R.2
  • 12
    • 37549043217 scopus 로고    scopus 로고
    • Toll-like receptor signaling in macrophages links the autophagy pathway to phagocytosis
    • Sanjuan MA, Dillon CP, Tait SW, et al. Toll-like receptor signaling in macrophages links the autophagy pathway to phagocytosis. Nature 2007; 450: 1253-1257.
    • (2007) Nature , vol.450 , pp. 1253-1257
    • Sanjuan, M.A.1    Dillon, C.P.2    Tait, S.W.3
  • 13
    • 79955532516 scopus 로고    scopus 로고
    • TLR signaling augments macrophage bactericidal activity through mitochondrial ROS
    • West AP, Brodssky IE, Rahner C, et al. TLR signaling augments macrophage bactericidal activity through mitochondrial ROS. Nature 2011; 472: 476-480.
    • (2011) Nature , vol.472 , pp. 476-480
    • West, A.P.1    Brodssky, I.E.2    Rahner, C.3
  • 14
    • 0033591428 scopus 로고    scopus 로고
    • Phylogenetic perspectives in innate immunity
    • Hoffman JA, Kafatos KC, Janeway CA, et al. Phylogenetic perspectives in innate immunity. Science 1999; 284: 1313-1317.
    • (1999) Science , vol.284 , pp. 1313-1317
    • Hoffman, J.A.1    Kafatos, K.C.2    Janeway, C.A.3
  • 15
    • 39149130359 scopus 로고    scopus 로고
    • Sensing Gram-negative bacterial lipopolysaccharides: A human disease determinant?
    • Munford RS,. Sensing Gram-negative bacterial lipopolysaccharides: a human disease determinant? Infect Immun 2008; 76: 454-465.
    • (2008) Infect Immun , vol.76 , pp. 454-465
    • Munford, R.S.1
  • 16
  • 17
    • 68949210558 scopus 로고    scopus 로고
    • A single amino acid substituteon in PmrB is associated with polymyxin B resistance in clinical isolate of Pseudomonas aeruginosa
    • Abraham N, Kwon DH,. A single amino acid substituteon in PmrB is associated with polymyxin B resistance in clinical isolate of Pseudomonas aeruginosa. FEMS Microbiol Lett 2009; 298: 249-254.
    • (2009) FEMS Microbiol Lett , vol.298 , pp. 249-254
    • Abraham, N.1    Kwon, D.H.2
  • 18
    • 71249110157 scopus 로고    scopus 로고
    • Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa
    • Barrow K, Kwon DH,. Alterations in two-component regulatory systems of phoPQ and pmrAB are associated with polymyxin B resistance in clinical isolates of Pseudomonas aeruginosa. Agents Chemother 2009; 53: 5150-5154.
    • (2009) Agents Chemother , vol.53 , pp. 5150-5154
    • Barrow, K.1    Kwon, D.H.2
  • 19
    • 0034985868 scopus 로고    scopus 로고
    • Bacterial modifyion of LPS and resistance to antimicrobial peptides
    • Gunn JS,. Bacterial modifyion of LPS and resistance to antimicrobial peptides. J Endotoxin Res 2001; 7: 57-62.
    • (2001) J Endotoxin Res , vol.7 , pp. 57-62
    • Gunn, J.S.1
  • 21
    • 79960309927 scopus 로고    scopus 로고
    • The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17987 and clinical isolates through phosphoethanolamine modification of lipid A
    • Arroyo LA, Fernandez L, Hankins JV, et al. The pmrCAB operon mediates polymyxin resistance in Acinetobacter baumannii ATCC 17987 and clinical isolates through phosphoethanolamine modification of lipid A. Antimicrob Agents Chemother 2011; 55: 3743-3751.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 3743-3751
    • Arroyo, L.A.1    Fernandez, L.2    Hankins, J.V.3
  • 22
    • 79959261544 scopus 로고    scopus 로고
    • Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system
    • Beceiro A, Llobet E, Aranda J, et al. Phosphoethanolamine modification of lipid A in colistin-resistant variants of Acinetobacter baumannii mediated by the pmrAB two-component regulatory system. Antimicrob Agents Chemother 2011; 55: 3370-3379.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 3370-3379
    • Beceiro, A.1    Llobet, E.2    Aranda, J.3
  • 23
    • 84872045758 scopus 로고    scopus 로고
    • Real-time sequencing to decipher the molecular mechanism of resistance of a clinical pan-drug-resistant Acinetobacter baumannii isolate from Marseille, France
    • Rolain JM, Diene SM, Kempf M, et al. Real-time sequencing to decipher the molecular mechanism of resistance of a clinical pan-drug-resistant Acinetobacter baumannii isolate from Marseille, France. Antimicrob Agents Chemother 2013; 57: 592-596.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 592-596
    • Rolain, J.M.1    Diene, S.M.2    Kempf, M.3
  • 24
    • 84884253490 scopus 로고    scopus 로고
    • Unique structural modifications are present in the lipopolysaccharide from colistin-resistant strains of Acinetobacter baumannii
    • Pelletier MR, Casella LG, Jones JW, et al. Unique structural modifications are present in the lipopolysaccharide from colistin-resistant strains of Acinetobacter baumannii. Antimicrob Agents Chemother 2013; 57: 4831-4840.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 4831-4840
    • Pelletier, M.R.1    Casella, L.G.2    Jones, J.W.3
  • 25
    • 0141484326 scopus 로고    scopus 로고
    • Cationic antimicrobial peptides activate a two-component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa
    • McPhee JB, Lewenza S, Hancock RE,. Cationic antimicrobial peptides activate a two-component regulatory system, PmrA-PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa. Mol Microbiol 2003; 50: 205-217.
    • (2003) Mol Microbiol , vol.50 , pp. 205-217
    • McPhee, J.B.1    Lewenza, S.2    Hancock, R.E.3
  • 26
    • 0032850479 scopus 로고    scopus 로고
    • PhoP-PhoQ homologues in Pseudomonas aeruginosa regulate expression of the outer-membrane protein OprH and polymyxin B resistance
    • Macfarlane EL, Kwasnicka A, Ochs MM, et al. PhoP-PhoQ homologues in Pseudomonas aeruginosa regulate expression of the outer-membrane protein OprH and polymyxin B resistance. Mol Microbiol 1999; 34: 305-316.
    • (1999) Mol Microbiol , vol.34 , pp. 305-316
    • Macfarlane, E.L.1    Kwasnicka, A.2    Ochs, M.M.3
  • 27
    • 84893715511 scopus 로고    scopus 로고
    • Mutations and expression of PmrAB and PhoPQ related with colistin resistance in Pseudomonas aeruginosa clinical isolates
    • Lee JY, Ko KS,. Mutations and expression of PmrAB and PhoPQ related with colistin resistance in Pseudomonas aeruginosa clinical isolates. Diagn Microbiol Infect Dis 2014; 78: 271-276.
    • (2014) Diagn Microbiol Infect Dis , vol.78 , pp. 271-276
    • Lee, J.Y.1    Ko, K.S.2
  • 28
    • 84863393429 scopus 로고    scopus 로고
    • PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients
    • Moskowitz SM, Brannon MK, Dasgupta N, et al. PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients. Antimicrob Agents Chemother 2012; 56: 1019-1030.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 1019-1030
    • Moskowitz, S.M.1    Brannon, M.K.2    Dasgupta, N.3
  • 29
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O,. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 30
    • 0037317763 scopus 로고    scopus 로고
    • Innate immune sensing and its roots: The story of endotoxin
    • Beutler B, Rietschel ET,. Innate immune sensing and its roots: the story of endotoxin. Nature Rev Immunol 2003; 3: 169-176.
    • (2003) Nature Rev Immunol , vol.3 , pp. 169-176
    • Beutler, B.1    Rietschel, E.T.2
  • 31
    • 27144509163 scopus 로고    scopus 로고
    • A network-based analysis of systemic inflammation in humans
    • Calvano SE, Wenzhong X, Rihards DR, et al. A network-based analysis of systemic inflammation in humans. Nature 2005; 473: 1032-1037.
    • (2005) Nature , vol.473 , pp. 1032-1037
    • Calvano, S.E.1    Wenzhong, X.2    Rihards, D.R.3
  • 32
    • 33748416499 scopus 로고    scopus 로고
    • Cytokine storm in a phase i trial of the anti-CD 28 monoclonal antibody TGN1412
    • Suntharalingam G, Perry MR, Ward S, et al. Cytokine storm in a phase I trial of the anti-CD 28 monoclonal antibody TGN1412. New Engl J Med 2006; 355: 1018-1028.
    • (2006) New Engl J Med , vol.355 , pp. 1018-1028
    • Suntharalingam, G.1    Perry, M.R.2    Ward, S.3
  • 33
    • 34547515353 scopus 로고    scopus 로고
    • The host response to endotoxin, antilipopolysaccharide strategies, and the management of severe sepsis
    • Opal SM,. The host response to endotoxin, antilipopolysaccharide strategies, and the management of severe sepsis. Int J Med Microbiol 2007; 297: 365-377.
    • (2007) Int J Med Microbiol , vol.297 , pp. 365-377
    • Opal, S.M.1
  • 34
    • 0141814639 scopus 로고    scopus 로고
    • Bacterial pathogens modulate an apoptosis differentiation proGram in human neutrophils
    • Kobayashi SD, Braughton KR, Whitney AR, et al. Bacterial pathogens modulate an apoptosis differentiation proGram in human neutrophils. Proc Natl Acad Sci 2003; 100: 10948-10953.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 10948-10953
    • Kobayashi, S.D.1    Braughton, K.R.2    Whitney, A.R.3
  • 35
    • 62749164849 scopus 로고    scopus 로고
    • Triggering receptor expressed on myeloid cells (TREM) family and the application of its antagonists
    • Molloy EJ,. Triggering receptor expressed on myeloid cells (TREM) family and the application of its antagonists. Rec Pat Antiinfect Drug Discov 2009; 4: 51-56.
    • (2009) Rec Pat Antiinfect Drug Discov , vol.4 , pp. 51-56
    • Molloy, E.J.1
  • 36
    • 84925847753 scopus 로고    scopus 로고
    • Risks for multidrug-resistant pathogens in the ICU
    • Martin-Loeches I, Diaz E, Valles J,. Risks for multidrug-resistant pathogens in the ICU. Curr Opin Crit Care 2014; 20: 516-524.
    • (2014) Curr Opin Crit Care , vol.20 , pp. 516-524
    • Martin-Loeches, I.1    Diaz, E.2    Valles, J.3
  • 37
    • 84892457845 scopus 로고    scopus 로고
    • Polymorphisms of the toll-like receptor 2 and 4 genes are associated with faster progression and a more severe course of sepsis in critically ill patients
    • Nachtigall I, Tamarkin A, Tafelski S, et al. Polymorphisms of the toll-like receptor 2 and 4 genes are associated with faster progression and a more severe course of sepsis in critically ill patients. J Int Med Res 2013; 42: 93-110.
    • (2013) J Int Med Res , vol.42 , pp. 93-110
    • Nachtigall, I.1    Tamarkin, A.2    Tafelski, S.3
  • 38
    • 34250823515 scopus 로고    scopus 로고
    • Gene-specific control of inflammation by TLR-induced chromatin modifications
    • Foster SL, Hargreaves DC, Medzhitov R,. Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 2007; 477: 972-978.
    • (2007) Nature , vol.477 , pp. 972-978
    • Foster, S.L.1    Hargreaves, D.C.2    Medzhitov, R.3
  • 39
    • 84875703277 scopus 로고    scopus 로고
    • Antimicrobial resistance and virulence: A successful or deleterious association in the bacterial world?
    • Beceiro A, Tomas M, Bou G,. Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world? Clin Microbiol Rev 2013; 26: 185-230.
    • (2013) Clin Microbiol Rev , vol.26 , pp. 185-230
    • Beceiro, A.1    Tomas, M.2    Bou, G.3
  • 40
    • 78649650250 scopus 로고    scopus 로고
    • Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production
    • Moffatt JH, Harper M, Harrison P, et al. Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production. Antimicrob Agents Chemother 2010; 54: 4971-4977.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4971-4977
    • Moffatt, J.H.1    Harper, M.2    Harrison, P.3
  • 41
    • 84455161855 scopus 로고    scopus 로고
    • Colistin-resistant, lipopolysaccharide-deficient Acinetobacter baumannii responds to lipopolysaccharide loss through increased expression of genes involved in the synthesis and transport of lipoproteins, phospholipids, and poly-b-1:6-N-acetylglucosamine
    • Henry R, Vithanage N, Harrison P, et al. Colistin-resistant, lipopolysaccharide-deficient Acinetobacter baumannii responds to lipopolysaccharide loss through increased expression of genes involved in the synthesis and transport of lipoproteins, phospholipids, and poly-b-1:6-N-acetylglucosamine. Antimicrob Agents Chemother 2012; 56: 59-69.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 59-69
    • Henry, R.1    Vithanage, N.2    Harrison, P.3
  • 42
    • 70349136689 scopus 로고    scopus 로고
    • Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system
    • Adams MD, Nickel GC, Bajaksouzian S, et al. Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system. Antimicrob Agents Chemother 2009; 53: 3628-3634.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3628-3634
    • Adams, M.D.1    Nickel, G.C.2    Bajaksouzian, S.3
  • 43
    • 80052408400 scopus 로고    scopus 로고
    • Acinetobacter baumannii resistant to colistin alters its antibiotic resistance profile: A case report from Spain
    • Lopez-Rojas R, Jimenez-Mejias ME, Lepe JA, et al. Acinetobacter baumannii resistant to colistin alters its antibiotic resistance profile: a case report from Spain. J Infect Dis 2011; 204: 1147-1148.
    • (2011) J Infect Dis , vol.204 , pp. 1147-1148
    • Lopez-Rojas, R.1    Jimenez-Mejias, M.E.2    Lepe, J.A.3
  • 44
    • 80052400016 scopus 로고    scopus 로고
    • Acinetobacter baumannii resistant to colistin with impaired virulence: A case report from France
    • Rolain JM, Roch A, Castanier M, et al. Acinetobacter baumannii resistant to colistin with impaired virulence: a case report from France. J Infect Dis 2011; 204: 1146-1147.
    • (2011) J Infect Dis , vol.204 , pp. 1146-1147
    • Rolain, J.M.1    Roch, A.2    Castanier, M.3
  • 45
    • 84872031103 scopus 로고    scopus 로고
    • Characterization of the polymyxin B resistome of Pseudomonas aeruginosa
    • Fernandez L, Alvarez-Ortega C, Wiegand I, et al. Characterization of the polymyxin B resistome of Pseudomonas aeruginosa. Antimicrob Agents Chemother 2013; 57: 110-119.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 110-119
    • Fernandez, L.1    Alvarez-Ortega, C.2    Wiegand, I.3
  • 46
    • 10244260491 scopus 로고    scopus 로고
    • Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturaly transformation competent bacterium
    • Barbe VD, Vallenet N, Fonknechten A, et al. Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturaly transformation competent bacterium. Nucleic Acids Res 2004; 32: 5766-5779.
    • (2004) Nucleic Acids Res , vol.32 , pp. 5766-5779
    • Barbe, V.D.1    Vallenet, N.2    Fonknechten, A.3
  • 47
    • 33750580687 scopus 로고    scopus 로고
    • Genes involved in intrinsic antibiotic resistance of Acinetobacter baylyi
    • Gomez MJ, Neyfakh AA,. Genes involved in intrinsic antibiotic resistance of Acinetobacter baylyi. Antimicrob Agents Chemother 2006; 50: 3562-3567.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 3562-3567
    • Gomez, M.J.1    Neyfakh, A.A.2
  • 48
    • 49449103767 scopus 로고    scopus 로고
    • Induction by cationic antimicrobial peptides and involvement in intrinsic polymyxin and antimicrobial peptide resistance, biofilm formation, and swarming motility of PsrA in Pseudomonas aeruginosa
    • Gooderham WJ, Bains M, McPhee JB, et al. Induction by cationic antimicrobial peptides and involvement in intrinsic polymyxin and antimicrobial peptide resistance, biofilm formation, and swarming motility of PsrA in Pseudomonas aeruginosa. J Bacteriol 2008; 190: 5624-5634.
    • (2008) J Bacteriol , vol.190 , pp. 5624-5634
    • Gooderham, W.J.1    Bains, M.2    McPhee, J.B.3
  • 49
    • 0032519672 scopus 로고    scopus 로고
    • CD14-dependent internalization of bacterial lipopolysaccharide (LPS) is strongly influenced by LPS aggregation but not by cellular responses to LPS
    • Kitchens RL, Munford RS,. CD14-dependent internalization of bacterial lipopolysaccharide (LPS) is strongly influenced by LPS aggregation but not by cellular responses to LPS. J Immunol 1998; 160: 1920-1928.
    • (1998) J Immunol , vol.160 , pp. 1920-1928
    • Kitchens, R.L.1    Munford, R.S.2


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